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Friday, 3 March 2017

Is Definition of Diabetes Type 1 Right? March 3, 2017

The majority of cases of diabetes fall into two major categories of pathogenesis.
Type 1 diabetes mellitus is caused by absolute deficiency of insulin secretion. Individuals at risk for developing type 1 diabetes can be identified by serologic markers showing evidence of autoimmune pathological conditions occurring in the islet cells of the pancreas.
So, how the absolute deficiency of insulin secretion was detected or identified? As long as it is known, diabetics type 1 take less then 50 units of insulin. Another fact is that they can be in Honeymoon Phase, the state when there is no need in insulin injections. They do have normal level of insulin in blood, so any additional insulin added in injections would lead to dangerous drop in level of sugar in blood. And finally, there are many of them who take less then 10 units of insulin. In the same book by the same time Anne Peters present that:
Clinically severe insulin resistance is defined as a situation in which a patient requires more than 200 U of insulin daily dose for more than 2 days.The definition was coined more than 40 years ago, when it was erroneously believed that human pancreas secret approximately 200 units of insulin per day. Although it is now known that the normal pancreas secrets only 20 to 40 U of insulin per day, ...... . (P133)
Now say me, if diabetic type 1 takes less then 10 units of insulin, then is this really true that diabetic's type 1 pancreas absolutely does not secret insulin? Well, Anne Peters can believe in that, I do not. Also with absolute deficit of insulin secretion there is no way that diabetics can live without insulin, so there is no any honeymoon phase. Finally, if diabetic's type 1 get flu then diabetic will need more units of insulin, blood sugar will go up and up. At the same time, medical practice show that with age the dose of insulin diabetics type 1 need to support own life dropping. If there is no insulin secretion than there is no way that dose of insulin would drop with age, it would go up. The fact is right opposite.
      Now, go back to definition and identification of diabetes type 1. Authors, Anne Peters and Ruchi Mathur, present that those in risk to develop diabetes type 1 can be identified by serologic markers. A little bit confusing for me to take it as a true.  According to many cases studies all the time MD presented that diabetes type 1 developed in very speedy way, very fast. I already posted long time ago boy in ER with sugar level over 800 mg/dl. Two weeks before being admitted to ICU he had medical clinic, and no  one doctor identified he is diabetic type 1. He was not in risk of developing diabetes type 1. Was he already diabetic type 1? Who knows? There is no one data, no one test, no one mark to say, he was already diabetic type 1, so there were no one tes to check up if he was in high risk to develop type 1 diabetes. He already had all symptoms of diabetes, still there were no diagnose of diabetes type 1, and no treatment as a result. So, it is better to say that type 1 diabetes developed so fast that after being in clinic two weeks before with normal level of sugar, no one ever tested, he developed diabetes type 1 with level of sugar over 800 mg/dl. Easy to say, hard to believe.
      What I try to say, no one ever will take test to identify serologic marks. Right now with so easy test for level of sugar diabetics still out of diagnose.
      Why today, when every one out of ten is diabetic, why level of sugar in blood still not be Vital? It is easy to test, not expensive, just cost of glucose strip, less than $1, and there is no need to screening or expensive tests such as serologic markers.
       There are so many identifications and definitions what is diabetes, what is diabetes type 1 or type 2, and still, all definitions and identifications do not stand simple logical question. Really, diabetes type 1, what is it? Is this really absolute absence insulin secretion? Mot at all. There is no one test to support this claim. There is still no range for level of insulin healthy human normally needs during the day. It is every one do know that physical activity demand more energy, so it is demand in insulin. Regarding to what this demand increases or decreases?
        In book there are recommendations nutrition and activity, still, there is no recommendations how to increase insulin secretion. There are all recommendations how to decrease level of sugar with diet and Starvation, still, there is no one tip or recommendation how this actions such Starvation Diet effect insulin secretion by human pancreas.
       That's right, all treatment and medical recommendations how to decrease level of sugar in blood, still, symptom of diabetes. As it was presented right in the beginning, diabetes type 1 not the level of sugar in blood but absolute absence of insulin secretion.So, why treatment addressed to the symptom? Would be this treatment effective? Not at all. As soon as diabetic start to eat the symptom return, because of it is symptom, and it is not cause of medical condition.

Davidson's Diabetes Mellitus; Diagnoses and Treatment
by Anne Peters Harmel and Ruchi Mathut. 2004
ISBN: 0-7216-9596-5


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