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Sunday 30 September 2018

Leukemia and Diabetes type 2. September 30, 2018

Cancer needs energy to drive its out-of-control growth. It gets energy in the form of glucose, in fact consuming so much glucose that one method for imaging cancer simply looks for areas of extreme glucose consumption -- where there is consumption, there is cancer.
Interesting point, how to see the area where glucose consumption? 
Next point is,
what was first, diabetes when glucose level is high in blood, so cancer has great opportunity to drive it and grow?
or it was diabetes, limited insulin secretion that drive energy from body and left unused glucose run in blood stream?
Really, what is the Head and where is the Tail?
"Leukemia cells create a diabetic-like condition that reduces glucose going to normal cells, and as a consequence, there is more glucose available for the leukemia cells. Literally, they are stealing glucose from normal cells to drive growth of the tumor," says Craig Jordan, PhD, investigator at University of Colorado Cancer Center, division chief of the Division of Hematology and the Nancy Carroll Allen Professor of Hematology at the University of Colorado School of Medicine.
What started first, diabetes or leukemia? Diabetes. So, there is no way that Leukemia  may create diabetes-like condition. So, if take the fact that Leukemia kill victim faster then diabetes then start to treat diabetes with Insulin and let glucose enter into cell so glucose will not be available for feeding leukemia cells. So simple, diabetes must be treated. Most important, it can be effectively treated today. Two Lantus Solo Star pens for month as soon as blood sugar getting up compare with normal range, and there is no leukemia because of there is no sugar available to feed cancer cells. It is just two boxes for 5 months.
      In our education it is all time said that normal level of sugar in blood is between 70 and 99 mg/dL. So, as soon as sugar in blood is over 70 mg/dl. start to take Insulin, from 10 to 20 units daily. There is no pre-diabetes or any types of diabetes. In modern medicine the level of insulin in blood is never tested. So, only level of sugar can be used. At the same time the level of sugar is easy to check up, and keep under control with proper way to treat it. There is no effect on life such as Life style modifications or diets or any Trash medicine such as Invocana or Metformin. No any weight issue to abuse patients and all people around. Simple, be healthy and well. 
     No, this is not the goal for Med Pro. Healthy people no longer paying people. treatment of diabetics with insulin will have too high effect on economy of America and all western countries. It is better to drive immigrants from around the world, and fight with terrorist then let own people to live and work and be happy and well.
    The article is big, and today is Sunday. I prefer to watch Video of play games, or simple to go outdoor then read all brain washing Trash authors created to show up how smart they are. The matter of fact, I am simple person and really very lazy. I prefer simple way in everything, including my treatment. So, as I posted many times,
let make Level of sugar Vital;
let start Insulin Therapy as soon as level of sugar over 70 mg/dl;
let get insulin dose up if sugar still getting up and up, just to keep it under 99 mg/dl.
What if this is the way how to reduce mortality of diabetics type 2 who collects more and more complications and pounds, till finally one of complications finally cut miserable life. 
    There are many studies what medicine take after life style modifications and Metformin. There are no studies, how to use Insulin for diabetics type 2. No studies. Why?  Really? Who will take Invokana and Metformin if Insulin will done the job?


Cancer hijacks the microbiome to glut itself on glucose.
Source: University of Colorado Anschutz Medical Campus
 https://ift.tt/2RdmSvS


via Ravenvoron

Saturday 29 September 2018

Dropping Four Research Programs

Every year in September or October I write a blog posting which summarizes all research being done in humans, aimed at curing type-1 diabetes.  That blog is going to be published in 2-4 weeks.   While putting that blog together I have found several research projects which I should not cover any more, and I'm listed those here, with a brief note on why they are no longer of interest.

I understand that this posting is a downer, and I'm sorry for that, but it is important to know what studies are no longer looking promising, and why.  Research naturally gets a lot of press when there is good news, but it's important to keep track of the bad news, and the "no news is bad news" situations as well.

Dendritic Cell Therapy  (DV-100) by DiaVacs
This trial was supposed to start in 2013, but never did.  The company is working on a follow on product, DV-200, and when that starts clinical trials I will follow it.  But since there has been a five year break between DV-100 and DV-200, I'm going to wait until a trial actually starts before restarting coverage.

BCG by Faustman at Harvard
This research is being removed for two reasons:
  • Her phase-II trial is not using C-peptide data as either a primary or secondary outcome.  C-peptide is the standard measure for progress to a cure, so not having it as a primary or even secondary outcome means this research is no longer "aimed a curing type-1 diabetes".  (I will continue to follow it, and especially any C-peptide data that comes out, but unless C-peptides are a primary or secondary outcome, it is not cure focused for me.)
  • The phase-I trial extended results show that Dr. Faustman's original theory (the TNF theory) of how BCG might cure type-1 diabetes is wrong.  The paper said specifically that the theory did not explain the results seen, and presented a new theory.  However the new theory is based on how the body digests carbs (not regenerating beta cells), and therefore is not a cure focused theory.  (Indeed, several type-2 diabetes treatments are based on similar theories).  So even if this theory is correct, the result would be treatment, not cure.


Obviously, this research group is continuing to talk about curing type-1 diabetes, but one the rules of my blog is "Actions speak louder than words" and if the clinical trial is not focused on C-peptide data, I don't think they are focused on a cure, no matter what is said.

Rilonacept by White at University of Texas
This group published their phase-I results in June 2018, but they were unsuccessful: "Rilonacept treatment for 6 months is well-tolerated in individuals with T1D of recent onset, but is unlikely to be efficacious as a single agent in preserving beta cell function."  So I don't expect any follow up work.

The Sydney Project (Encapsulated Stem Cells)
I can not find any recent references to this project.  The closest I can find is an encapsulated stem cell project being funded by the Australian Foundation for Diabetes Research.  It is doing animal research right now, so not clinical trials.


Joshua Levy 
https://ift.tt/29DuN3o 
publicjoshualevy at gmail dot com
All the views expressed here are those of Joshua Levy, and nothing here is official JDRF, JDCA, or Bigfoot Biomedical news, views, policies or opinions. In my day job, I work in software for Bigfoot Biomedical. My daughter has type-1 diabetes and participates in clinical trials, which might be discussed here. My blog contains a more complete non-conflict of interest statement. Thanks to everyone who helps with the blog.


via Cure Research

Friday 28 September 2018

Personalized Medicine, Combo Tx, Stops Progression to Diabetes. September 28, 2018

The lowest doses considered to have a physiological effect were used, 850 mg/day for metformin and 15 mg/day for pioglitazone. For the GLP-1 receptor agonist, medications were used based on insurance coverage: exenatide 10 μg twice daily (n = 26), liraglutide 1.2 mg daily (n = 49), exenatide extended-release 2 mg weekly (n = 3), or dulaglutide 1.5 mg weekly (n = 3). Doses of the GLP-1 receptor agonist were not modified during the study.
This is Combo of medicine to stop pre-diabetes to progress to be full diabetes. So, what is on the table?
The block Box for Pioglitazone (Actos)
Pioglitazone and other similar medications for diabetes may cause or worsen heart failure (condition in which the heart is unable to pump enough blood to the other parts of the body). Before you start to take pioglitazone, tell your doctor if you have or have ever had heart failure, especially if your heart failure is so severe that you must limit your activity and are only comfortable when you are at rest or you must remain in a chair or bed. Also tell your doctor if you were born with a heart defect, and if you have or have ever had swelling of the arms, hands, feet, ankles, or lower legs; heart disease; high cholesterol or fats in the blood; high blood pressure; coronary artery disease (narrowing of the blood vessels that supply blood to the heart); a heart attack; an irregular heartbeat; or sleep apnea. Your doctor may tell you not to take pioglitazone or may monitor you carefully during your treatment.
It is simple and easy to understand, three is better then one. So, not for those who are only on the start of long fatal way, let them be treated as soon as it is possible, to speed their way to the final end. It is the same as when one get flu. let them Rx ice bathing, and see if Flu never will be developed.
      I do not see any reason to start this treatment. Why there are no studies in this trail just slow dose of Insulin, right after diagnose any elevation in blood sugar level? Really, why do not add to this medicine which was studies, well known and relabel medicine, Insulin?  At least some of this medicine the same as Insulin, must be injected. So, add insulin, Lantus Solo Star, and see if blood sugar level will go down. There are no risk so fat. Dose of insulin is small, less then 20 units, not really very expensive. In every pen there are 300 units of Insulin. 2 pens for month is good to start. Then will see, if dose will dropping, and how fast sugar in blood will return back to normal.
"However, the complications of type 2 diabetes can be devastating and anything that can be done to avoid diabetes and therefore its complications is worthy of consideration."     
Why diabetes type 2 progress to so sever complications? Because treatment of diabetes type 2 is wrong. So it is treatment which leads to complications development. Without treatment diabetic type 2 will live longer, even still ill and weak. At least diabetic type 2 will be alive.With medicine to treat diabetes type 2 diabetic die less then within 10 years after being diagnosed with diabetes type 2. Looks like Medical Care progressed in own Greed, and now treatment started early, to prevent progression to diabetes. Nice try. At least Medical Pro never will be left without life stock.
A third group of 200 patients (76 high risk and 124 intermediate risk) who refused pharmacological therapy were assigned to lifestyle therapy only.
At a mean follow-up of 32 months, 28 of the 422 (7%) patients developed type 2 diabetes.
What MD ask studies?
Family Medicine:
How long was the study?
Did they really stop the progression or just mask it for a while?
        Really, how it was determined that progress was stopped? level of sugar in blood is very manipulative. Just simple manipulation with time when sample was taken can give result researcher need to have and to show. Immidiate level of sugar in blood does not show if diabetes in progress or progress was stopped with combo medicine.
        Another question is, for how long pre-diabetic must take this combo? If it is life long therapy then really how to see if it is wrong prediction or it is effect of medicine. In contrary, with Insulin most diabetic type 1 decreased dose of injected insulin. The matter of fact, many have "Honeymoon phase" when injection of insulin were stopped for awhile.
      Lastly, how this combo therapy can be "personalized"? All patients got the same combo. If it will be in ADA guidance, then all American Diabetics type 2  and per-diabetics will have the same combo to prevent, to treat diabetes type 2, even when sugar in blood in fatal level. Only those who collected money from this studies can see overspecialization in this kind of therapy. They see all what customer ask them to see. Who Is Your Daddy?


Personalized Medicine, Combo Tx, Stops Progression to Diabetes
by Nancy A. Melville
https://www.medscape.com/viewarticle/902316?nlid=125212_381&src=WNL_mdplsnews_180928_mscpedit_wir&uac=164666HZ&spon=17&impID=1753252&faf=1#vp_2


via Ravenvoron

Diabetes type 2 from inside out. September 28, 2018

Diabetes type 2 considered to be mild type of diabetes which can be easily reversed with diet and work out. Where this understanding come from? It is rooted from the media propaganda and medical misrepresentation of the severe potentially fatal medical condition which they avoid to treat. Why they do not want to treat diabetes type 2? The simple answer can be seen back to time when Consumption took lives one million after another.
Small village in Adirondack Up Staate of NY, Saranac village became known as Cottage sanatorium. In May 25, 1873 Doctor from NYC come to Adirondack. He was effected by Consumption, and it was estimated, he has short time to live. But he survived, got better and soon he returned to NYC to take his wife and child and returned back to Adirondack. Here he started to build a new opportunity to those who did not have any hope. He did not get cure for Consumption, TB in present time how it was re-named later. He died because of TB. But at the time when he died many cottages were built, and many fives was saved.
 There are three generations of doctors who devoted lives to fight one of the most devastated disease, TB.
      Today we all do know that TB is not fatal, and treatable, does it? What we do not know how bacteria adapts to the new treatment, and still takes lives of people. It is not in our families, and we do not really so worry about it.
       How TB related to Diabetes? Well,
Finally, the chemotherapy era arrived in tuberculosis. SM, Para Aminosalicylic acid, Isoniazid were found to be effective drugs when used properly. This led to a change in both medical and surgical treatment of pulmonary tuberculosis. It was now safe to remove diseased lung rather than collapse it. This meant not only more effective therapy, but also that surgical treatment could be applied to those patients who formerly could not withstand collapse procedures. However, it became apparent from study and experience over years that drugs alone, when scientifically administered, were highly effective in the treatment of tuberculosis, even in the most advanced cases. This brought another change to Ray Brook. The period of hospitalization could now be decreased, and more patients admitted for treatment in a year. Surgery was no longer necessary for most patients. It was no longer necessary to come to the mountains for treatment and, moreover, there were fewer new cases of tuberculosis so in 1965 the Sanatorium Building was closed. Bed capacity was reduced from about 350 to 100 beds, and all the patients were now hospitalized in the Infirmary Building.
     The end of Consumption era. One after another TB sanatoriums were closed. Some buildings still used as corrected facilities, or any other   purpose. Many just   abandoned and can stand today without use. What about those  who worked there? Nurses packed uniforms and went out to find another job. Doctors needed another practice.
      This is not so long history. But it is real. Today there are millions of diabetics type 2, and we all need medicine, medical and home care. With population getting older more of us survive after we retired. But our health does not get better. It getting worse. With proper medicine and proper medical care we will live longer. It is good for Medical Industry. Still, it does not mean we need more and more medicine and medical care. Without diabetes type 2 many clinics will out of job. Mo need in nurses, or Invocana. Elderly people live pain-free. If there is no pain then there is no medical visits necessary. History repeat itself.
       Diabetes type 2 curable. If it will not be cured in first generation then in second or third it will be. With insulin as prime medicine diabetics type 2 would not die less then withing 10 years after being diagnosed with diabetes type 2.
      How treatment of diabetes started? Diet and work outs. Increased activity. It is stated that diabetes type 2 caused by low activity of diabetic. I am diabetic. I run my studies, and I am good observer. Yesterday it was very active day for me. It is not that I went to work out, I did not. But usually I sit at home and watch TV. Yesterday it was household activity, and I had to do a lot of job. What about today? Did my sugar dropped? Not at all. The matter of fact it is higher on 50 points. Why? Because our medical educators have no one idea how human body work and what really true and what is simple speculations. There are no studies, just Junk Manipulations in favor of Medical Industry.
      All diabetics need to watch diet. Why? Because of we eat our sugar rise. Is sugar rise only in diabetics body system? Not at all. All human bodies have blood sugar raised with first bite we take. Then sugar drops down to normal range withing one or two hours. If one is not diabetic. In diabetic sugar still rising after two , three, four hours. This fact never mentioned by Med Pro. They base their diagnose on normal healthy person. But we are not normal. We are diabetics type 2. Most important that regardless what I eat and how much I do eat, I still hungry. Hunger is one of symptoms of diabetes. The treatment? Stop to eat. Is this possible to work? Not at all. It is possible to overstep this hunger. Then diabetic cannot eat at all. Soon there is coma. 
       Simple shot of Insulin will prevent Death. There is no Insulin in mdiabetic's type 2 medical box. We have to avoid eating, and increase activity. Diabetes type 2 today is number 7 cause of Death, and it is getting higher. Americans getting wider, in attempt to survive.


via Ravenvoron

Tuesday 25 September 2018

A New Reason to Be Wary of SGLT2s September 25, 2018

There are reports of a rare but serious bacterial infection in patients taking common SGLT2 inhibitors for diabetes. In response, the US Food and Drug Administration (FDA) issued a warning about necrotizing fasciitis of the perineum, also known as Fournier gangrene.
Symptoms of the infection begin as early as 1 week and as late as 2 years after starting the drug. Out of 12 case reports to the FDA, seven were men and five were women, ranging from 38 to 78 years of age. All 12 patients were hospitalized and required surgical debridement. Four patients developed serious systemic complications, including septic shock, and one patient died.
There are some responds to this article. I cannot post my response because of I am not Med Pro. They do not take responses of patients. o, I post it here, on my blog
 But virtually all diabetes meds that are not Metformin or insulin have massive side effects.
Insulin does not have side effects. The hypoglycemia is  not side effect but normal healing process. No one medical condition heals by steady down. It is all the time up - and - own. With time with Insulin Therapy high blood sugar getting lower. and low blood sugar does not drop to fatally low level. In diabetes type 2 this process takes years to recovery, many ups and downs. Still, it is not side effect of Insulin. It is how our human body survive, The same as with developing very high level of sugar it is getting up and down. But in the case of developing highest level getting higher and does not go down.
      It is right opposite with Metformin. Metformin has very severe side effects. And most important  part, it does not have healing abilities. Try to stop to take metformin and see, what happen with level of sugar. In case of Insulin sugar will go up right away, next day meter show that diabetic forgot to take shot. Metformin, in contrary does not effect level of sugar. Usually med pro insist that Metformin must be built in system before it will start to work. Still, side effect, poison effect, diabetic develop with first tablets one had swallowed.
All meds, vitamins, herbs, and supplements have up and down sides. HRS, MD, FACC
That's true.As I just pointed out above, the side effect and healing effects are not the same, even when day looks alike. Also when Death considered as side effect I am better to avoid this medicine and be with my pain and discomfort rather then be in coffin.
    Now, back to Invocana. This medicine was launched in 2014, as I d remember. Probably I am not correct. Now it is 2018. 4 years, and it is already so many warring. Diabetes type 2 is progressive disease. This means that it will not be cured in soon future, but it will accompany victim and get victim worse. What diabetes will do in incoming future? For how long this medicine can be taken? Also sugar in urine is one of sings of diabetes. How progress of healing would be measured or tested?
The drugs to be aware of include canagliflozin, empagliflozin, dapagliflozin, and ertugliflozin. These drugs are prescribed to 1.7 million people in the United States. The more common side effects are yeast infections, urinary tract infections, and low blood glucose when taken with other diabetes medication
 So, low blood sugar only when Invocana takken with other diabetes medication. If there is no low blood sugar then there is no healing. It is another diabetes medicine which give healing such as Insulin. So, why take Invocana in first place? Just why diabetic needs to take this so danger drag? Just take Insulin without Invocana, and there are no side effect left, just long road to recovery.
Patients taking SGLT2 inhibitors should now be counseled about the risk for necrotizing fasciitis in the genital and rectal areas, and assessed for signs and symptoms of infection. If suspected, stop the drug and start treatment immediately with antibiotics and surgical evaluation. Confirmed infections should be reported to the FDA.
Thank you so much, but I am better to say ?no? to Invocana, inject Lantus Solo Star, and do not need any surgery at all. I love my way must better.

A New Reason to Be Wary of SGLT2s  Arefa Cassoobhoy, MD, MPH
by Arefa Cassoobhoy, MD, MPH
https://www.medscape.com/viewarticle/901880?nlid=125169_1521&src=WNL_mdplsfeat_180925_mscpedit_wir&uac=164666HZ&spon=17&impID=1749492&faf=1

see also:
 Invokana Side Effects   http://www.ravenvoron.net/2014/08/invokana-side-effects.html

Invocana Deadly March  http://www.ravenvoron.net/2014/05/invocana-deadly-march.html

Invokana- Perfect Cure For Diabetics Type 2  http://www.ravenvoron.net/2014/02/invokana-perfect-cure-for-diabetics.html

 Invokana To Treat Diabetes Type 2 http://www.ravenvoron.net/2014/02/invokana-to-treat-diabetes-type-2.html


via Ravenvoron

Monday 24 September 2018

Diabetes In The Wild At The Harvest Moon Party~

Friday night I received a text to a Saturday night Harvest Moon party, promising good people, good fun, and a beautiful view of the moon.
Sidebar: Tonight (September 24th,) is the official Harvest Moon for the Americas - but it’s pouring buckets in my neck of the woods so I’m not sure I’ll see it. 

But I digress. 

Cut to Saturday night. I drove over to the party, parked my car and with pumpkin bread in hand, walked through the front door and into the kitchen - where I was immediately greeted with hugs and by people I haven’t seen in ages, while simultaneously being introduced to new faces. 

Thanks to kismet, I had two “diabetes in the wild,” encounters with two kick-ass women with personal and professional connections to diabetes. 

"Diabetes in the wild," encounter number one occurred outside on the deck - where my friend was talking to a young woman. I didn't know anyone out and the deck and felt like a dork. My friend motioned for me to come over. I did, he introduced us and mentioned that I wrote a Diabetes Blog. 
Turns out she was a grade school teacher who had a student with t1. 
She told me how she’d become aware of all things diabetes related and was learning more everyday. 
We talked about growing up with diabetes, she asked me about my low and high blood sugar tells and I told her.
Two weeks into the school year and this woman knew a lot about t1 and clearly wanted to learn more. Quite frankly, I WAS IMPRESSED. 
And IMO, her t1 student was lucky to have her as both a teacher and a friend. 
I gave Teacher Lady a few resources including CWD and Coco The Monkey.  
HELLO KISMET. As soon as I mentioned Coco, I remembered that I had a set of Coco books in my trunk. 
Sidebar: I was going to give the books to a local t1, but she already had them - so the books had been living in my trunk for a month.

I went out to my car; searched my trunk and found the Coco books, went back inside and handed them over. Teacher Lady couldn't wait to check them out over the weekend and then read them to her class!  

We exchanged numbers and I told her to keep in touch.
Later on in the evening, when I was bolusing via my Omnipod PDM for some crazy delicious autumn leaf sugar cookies, Teacher Lady walked over and said to me on the sly: You good? 
I told her I was and we both laughed. Girlfriend had my back and didn’t blink twice about me bolusing for cookies.

The second “diabetes in the wild” moment occurred later on in the kitchen, when I met a mom of a t1. dMama's daughter was now a mother herself and had lived with diabetes for over 3 decades. 
Like magnets to steal, we started talking about all things diabetes related. 
We discussed surviving the Diabetes Dark Ages, and dMama told me that the very first glucose meter her daughter ever used cost over a thousand dollars and wasn’t covered by insurance. 

We discussed scar tissue, diabetes idiosyncrasies, the cost of insulin, and everything in between. We talked about diabetes challenges - back in the diabetes dark ages and ones we struggle with in real time.
I told dMama about the Diabetes Online Community and peer support and gave her some links and info I thought her and her daughter would find helpful. 
Once again I found myself exchanging contact information with someone who “got it.” 

As I put the key in the ignition, I looked up at the moon, partially hidden by deep purple and navy night clouds, and thought about how we are all connected - and how once again, diabetes proves it. 
The amazing kick-ass women I’d met both live near me, each with personal and professional connections to diabetes, and I’d never met either one of them until now - even though we shared mutual friends. 

Bottom Line: The universe is a big, the world is smaller than we think - the world of diabetes - even smaller. The moon is magic, the universe knows what it’s doing - and we are meant to meet exactly when we do. 


via Diabetesaliciousness

Day -by - Day. September 24, 2018

      Sugar getting down. I decreased dose of insulin to keep it in normal range, ether not high nether too low. It is interesting what can be found when take a closer look and careful observation on own numbers and own feelings. We relay on MD, and usually suppress our own understanding and simple logic. What MD stand for? Own safety. For this reason medicine replaced by Cook Book. Really, take a look at the education  how we have to be treated or what we have to do to prevent timelss deaths? Eat right. Where this statement come from? Do we all, millions, 8 millions of diabetics, eat wrong? 95% of diabetic population are diabetics type 2. It is said that the cause of diabetes type 2 well established, It is caused by high calories intake. If someone easy to let own brain to be washed then I am not.
        I am not med pro, and I do not consider myself to be a scientist. But I am reasonable person and very well observer. Also I like to wright, which is easy to see how many posts I already put on this web. What I suppose to wright every day about? Only my observations and my feelings.
       In past medicine was more observational. In present time it is ideological. Studies show what profit demand. Simple, if there is no money then why work on it? Another point of modern medicine is safety of MD and Med Pro. So, no one of them will take risk to treat patient if there is some risk. To be sure that there are 100% risk-free, patients sent out of clinic or hospitals as soon as it is possible pretending that there is nothing happened, patient safe to go home.
    Now I watch TV show House. In this show Dr. House take most controversial and most difficult cases, because of he likes challenge, and do not like to do boring job like clinic. In reality I never met any Dr.House. Because of my case is difficult usually I sent home right after I am able to stand on my feet, usually after midnight. Dr. House used to say, he never lie to patients. In reality, as patient I never was told any true. Prove? Diabetes type 2 my diagnose, what does it mean? Never answer to this simple question. Only one response every time, diet. I was size 14, and 13, 110 pounds. Now I am size 6X 380 pounds. Still the treatment for my condition all the time is the same: work out and diet. This is how I got MI, strokes not fatal one after another, and many other complications.
      For me it is past. Now I am not in trust in MD. I am Observer, very good one. I look at what work for me, and try to keep my brain out of laundry media machine. I do not fight, do not see any reason in that. But do not try to put spaghetti on my ear. I refuse to carry it.
      So, what is new for today?
      My eyes still discharge some wight staff, but it is mot so much as it was recently. Looks like it is drained out.
      My legs still sweling. I wear wrapping all the time. But legs need some rest, and periodically I stay without wrap. Just a few days and legs get very very wide, swelled, and I start to have more difficulty to walk. Still, there are no wounds, skin is dry so far. Of cause 380 pounds is too much to carry on. I am almost do not walk, and when I do I walk on very short distance, and right away out of breath. The matter of fact I am very satisfied. At least I do not have wounds and I hope I will not be amputee in short future.
      My teethes are crashed very severely. Recently there was some dental work, but not all was done because of too much to pay, and another work must be done in incoming January. For my very disappointment, dentist ask me for money after work was done. It is not too much, just $27.40, as his desk lady said. I will not pay even $0.40. The point is not the sum I have to pay. I simple refuse to do Milking Caw job. I asked to send me bill, and I will ask health plan to pay this bill. So far there is no bill. But now I do worry, do I still have this dentist or have I work out to find another one?
      After I learned the problem with my teeth I though it is because of I take too much Excedrin. It is Aspirin, and as doctor said it might make hole in my stomach. So, I stopped to take it. Headache returned. It started to be more and more severe. Then there was pain in chin. Looks like I started to develop clots in blood, more and more. There are nothing what I could do. My man said, I can have all fake teethes, but if I will got stroke I will not have fake brain. So, I returned to the my loved Excedrin. Now headache eased.
     What else can I say? I do not have blurred vision so far. I have to go to vision center. I need usual annual check up. Still, I use the same reading glasses as it was a few years ago, meaning, vision does not get worse.
     Weight. It still the same even dose of Insulin increased very dramatically, from 300 units daily to 720 units highest dose which was injected. Now dose of insulin dropping and returned back to something 400 units and less. But with so high increase in Insulin injections the weight still the same, 380 pounds. Of cause it is too high. It is too difficult to walk. I cannot dress by myself. Still I am able to walk a short distance. At leas I do not ride my scooter at home, only outside.
      I think it is all for now.


via Ravenvoron

Sunday 23 September 2018

Sub-types for type 2 diabetes. September 23, 2018

Most patients diagnosed with type 2 diabetes are treated with a "one-size-fits-all" protocol that is not tailored to each person's physiology and may leave many cases inadequately managed. A new study by scientists at the Broad Institute of MIT and Harvard and Massachusetts General Hospital (MGH) indicates that inherited genetic changes may underlie the variability observed among patients in the clinic, with several pathophysiological processes potentially leading to high blood sugar and its resulting consequences.
Very promising introduction.  What do they suggest?
The work represents a first step toward using genetics to identify subtypes of type 2 diabetes, which could help physicians prescribe interventions aimed at the cause of the disease, rather than just the symptoms.
         There are one out of then Americans who is diabetic. 95% of Diabetics population are diabetics type 2. How many diabetics type 2 will die till treatment, even if it will be found according to the new studies, will available for common diabetics? In present time diabetes is number 7 cause of Death in America. Also, according to Med Pro publications, Diabetics type 2 die withing 10 years after being diagnosed with diabetes due to all - cause Death, if they do not start to take Insulin in injections. If they do, and Insulin Therapy is is right regime in right dose, they survive, and will start to recovery. If they do not, complications will be collected, and Death due to heart attack, or stroke, or cancer, or any other medical complications, will follow.
       So, study identified sub-types of diabetes type 2. I did not get how many still, it is diabetes type 2, and this medical condition still be treated with all available Junk Medicine but not with Insulin. One after another a new medicine enter to the market. The number diabetics type 2 who dies every year getting higher and higher.This fact raised a very reasonable question.
 If diabetes identified by level of sugaar in blood, and level of sugar in blood run from 100 mg/dl to over 1000 mg/dl, is this possible that there are only one stage in diabetes type 2 development?
       Not at all. Studies which were done by some group in IUC identified that then higher level of sugar in blood then less chance diabetic will survive.Then higher level of sugar in blood then more complications diabetic type 2 does have. So, according to that studies, the level of sugar in blood play most significant role in Diabetes survival and well being. If take this level of sugar in blood and body mass it will be also very visible that level of sugar is higher in obese diabetics, and body mass less in those diabetics who has less sugar in blood.
      How many types of diabetes?
Type 1, type 2, Type 1.5 (LADA), Mody, Idiopathic diabetes, gestational diabetes, pre-diabetes, non-sugary diabetes, sugary diabetes, insulin-dependent diabetes, insulin resistant diabetes, insulin independent insulin-resistant diabetes, and list go on and on.
Now in addition to this list types of diabetes another division was identified, sub-types of diabetes type 2, not type 1, but sub - types of diabetes type 2.
        It is understandable that type 1 diabetics are very angry. It looks for them that type 2 diabetics got all attention, and they are, type 1 diabetics, got nothing. The point in it is only one. Type 1 diabetes still on the list of diagnose. This is why only 5% of all diabetic population, millions of us, diagnosed with type 1 diabetes. LADA, MODY and all other types of diabetes fill into 5% of diabetic population. 95% of diabetic population is type 2 diabetics. This population needs to be treated. We live in constant pain, in suffering and everyday fear that we are getting worse. In contrary with type 1 population who take insulin, and health getting better, no complications, no obesity, no humiliation. We are guinea pigs for costly medical studies.
It's known that type 2 diabetes can be broadly grouped into cases driven either by the inability of pancreatic beta cells to make enough insulin, known as insulin deficiency, or by the inability of liver, muscle or fat tissues to use insulin properly, known as insulin resistance.
The first question to this statement, how do you know it? Is there are studies were done what is insulin resistance and when it is insulin deficiency? Never. No one studies like that. To run these studies level of insulin needed for daily activity must be identified. What is this level? No one publication in this direction. No one every studied how much insulin human body use in normal daily life. The same about insulin secretion by every one human body. No one ever tested what is the level of insulin secretion does diabetic type 2 pancreas. In modern time there is no any technology available to do studies like that. So, the statement on which all studies are based is fake. What is possible to say about study? It is fake study. Nothing more what can be said. There are no foundation under this building. With first argument it fall apart.
      Still I love the part that sub-types of diabetes type 2 identified. BTW, how many sub-types of diabetes type 2 was identified? I lost in reading. Anyway, in stead of study and create a new types for one medical condition why do top identify stages of this medical condition? There are different treatment for flu and pneumonia, for stage 1 kidney failure and stage 4 kidney failure, and so so on. Why diabetes is only one stage? It is long, really very very long way to walk from 100 mg/dl to 770 mg?dl, from A1c5% to A1c 12.4 %. So, why to not identify stages of diabetes and according to stages of diabetes develop standards what dose of insulin diabetic type 2 need to recovery?


Genomic study brings us closer to precision medicine for type 2 diabetes.Really?
by: Broad Institute of MIT and Harvard
https://www.sciencedaily.com/releases/2018/09/180921151441.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine%2Fdiabetes+%28Diabetes+News+--+ScienceDaily%29
 


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Friday 21 September 2018

Low-Carb Diets: Science or Politics? Or How I have to Eat? September 21, 2018

The low-carbohydrate diet has been shown in clinical trials to reverse diabetes, lead to weight loss, and improve most heart disease risk factors, all of which logically should lead to longer life.
       This statement based on what? Clinical trials. The point is, how diabetes type 2 was reversed, and really what does it mean, to reverse diabetes type 2? I am diabetic type 2. I straggle with this problem every day, day after day, year after year, all my life. I wish to understand, what does it meal, "reverse diabetes"? There are no one answer to this very simple question, every one use to insist it is real one easy to do.
       When I read how other diabetics type 2 present they reversed diabetes type 2 I see only one point, level of sugar in blood. Sugar in blood is tricky. Today it can be normal and good, then it can be low, and after being low it is getting up, very unexpectedly. Even when someone said that A1c dropped, it still do not prove that diabetes type 2 reversed. Tricky, is not it? Then say me, what does it mean, to reverse diabetes type 2?
      Level of sugar in blood can be normal, and for very long time. Is this prove that diabetes type 2 was cured? No. But it is considered as being reversed. Why this so confusing word become so popular in Med Papers? Because of if say that diabetes type 2 was cured, then why there are diabetes pandemic in the effect? Why diabetes type 2 is number 7 cause of death in CDC mortality tables? So, med pro smart move that diabetes type 2 can be reversed if diabetic stop to eat, stave. It works perfectly. Thousands posts how simple to reverse diabetes type 2. "If I could do it, then every one can do!"
Oldways is funded by grain processing companies and so the bias on the part of Harvard is understandable. Same funded bias exists with the American Heart Association, the American Diabetes Association, and the American Cancer Society that all promote red meat and processed meat products in their diet recommendations and sample recipes. But then if these life style diseases did not exist the people working at these places would be out of a job.(Comment by someone member)
Really, just think about, if there is no low carb diet then what MD will talk about when diabetic come to clinic? Not possible. Even all mortality will be higher then 99% because of Low-carb dieting, Med Pro will defend our life style on low carbs.
It's remarkable that the authors made such definitive claims about "low-carb diets," as the paper defined this diet as up to 37% of calories from carbohydrates—not "low-carb" by the latest standards of practice. Evidence from the past 5 years shows better health when carbohydrates are kept below 30% of calories, with the greatest benefits, including reversal of type 2 diabetes, seen with a very low-carb or ketogenic diet, where carbohydrates normally total between 5% and 20%.
       Authors of this article insist, there were no actual studies. But what and how to study lifestyle? How to study what people eat? Usually it is just ask questions, and consider it is true. Real studies are very different. Go to market and see  what is on the shelves, and how much people buy. What products are most popular in shopping card? How much people spend on what products, low carbs or high carbs? For instance, to see if economic in good standing, take a look at the sale of men underwear. Do not ask men what they wear. Just look at the sale.
     When it is pretended that one is on the low carb diet, how it is possible to see? Body weight will show amount of pounds, but there is no scale to show how much water in the body. Water does not have carbs or calories, no sugar and no salt. Water is pure. Still, water has weight, pounds, and obese person carry these pounds. Water sing its songs in lungs of victim. Pulmonary embolism. Heart is oversized. Water retention. Kidney failure. Water leads to all cause of death:  heart attacks and strokes, COPD and asthma. There are no medicine to fight water obesity, no diagnose, nothing.       On scale we see that person is obese, and Barking Therapy right now in the effect. No one MD see the Water on the scale.
      So, what are evidence that show Diabetes type 2 reversal? 5 years is long way to go. Is this true that 5 years the same people were observed who reversed diabetes type 2? Not at all. 5 years were pretended that they run studies, and they collected money. Then they counted how many lives were saved with low carb diet. But Mortality table still show, diabetes type 2 is number 7 cause of death. In NYC it is number 4.
Weak associations are overwhelmed by other issues known to affect health, called confounders. For instance, whether a person drinks, smokes, exercises, or even goes to church has an effect on health—no one really knows how much—and researchers must try to adjust for all of them. Perhaps an unknown factor, such as an environmental toxin, has affected someone's health. Epidemiologists cannot adjust for that, as they will not have measured it.
If there are so many factors that effect our health, then why it is pretended that Diabetes type 2 is caused by high fat high calorie, high carb diet? Let us be consistent.  No one know why we are diabetics type 2. There are no treatment for us when diabetes diagnosed. Just moderate own life. Simple, stop to eat. Starve yourselves. This will reverse diabetes type 2.
With so high mortality and cost of diabetes why level of sugar still not vital? BP and Temperature of body, X-ray and EKG, and blood work, cholesterol and many other tests are run every time we are in clinic. Even test of drugs for every one of us, and test on STD. The level of sugar is not on the table. With every one out of ten being diabetic, there are no blood sugar level to check up, why? It is easy, cheap, and very fast. Before start to treat patient check up level of sugar and see what treatment must be.
       It is not in Med Pro interests. It is easy to publish crap what diet is best, low carb, high carb, no carb, and so on. How to moderate  diabetic type 2 life when one is in hospital and sugar is over meter limits? There are two ways to deal with situation. One way is to send patient out, to take care what is on plate, to reduce weight. Another way is to start Insulin Therapy. If Insulin was started, it is cannot be stopped just after a few days in hospital. So, diabetic became insulin-dependent insulin-resistant diabetic type 2. So, usually MD in hospital take first choice. It is easy, and safe. Just Rx Healthy Life Style, and send victim at home.
 The Lancet paper asserts that this weak evidence should somehow trump the far more rigorous data from randomized controlled clinical trials. These are considered the gold standard of science, simply because, whatever their flaws, they can demonstrate cause and effect. This more sound science is ignored by the Lancet authors in two ways.
Probably this is Gold Standard. But I am not scientist. I am just diabetic. For me evidence is only one, level of sugar in my blood with common daily activity. If level of sugar dropping, then medicine I take is right. If not, then I have to find another treatment with higher effect. So, in my Gold standard Low carb diet is not common. When I have to force by body every day to suffer, then it is not healthy way to live.
My Gold Standard:
Be free of pain any cause;
      hunger is not good for me. I start to have headaches. If I avoid to eat then I can finish up in hospital, or have stroke.
 So, no hunger, no suffering, just be happy and sound.
Take medicine what I need, and do not take medicine that give me no benefits. 
      It is easy to say, but so difficult to do. How do I know what medicine is good and what is not?  I do not know, but I try. This is why I study medicine, medical problem, and the way how it is effected by society. This is my politic. I try to run my log book, and in this book all medicine I take, when it started, and why it was stopped, and when. When did I have some treatment or visit to hospital or clinic, and how effective this visit was.
 Take time to see, what is can be cause, and what effect, when the head, and what is the tail. To see something Big we need bigger distance.
The Lancet authors, in recommending a "moderate" diet of 50%-60% carbohydrates, also ignore another body of gold-standard evidence—on exactly this diet. The "moderate" carb, low-fat diet has, after all, been enshrined as our existing official dietary guidelines for Americans for decades. Ever since the late 1970s, when the Senate launched the Dietary Goals for the United States—which later became the basis of the food pyramid—the government's number-one goal has been to "increase carbohydrate consumption to account for 55%-60% of the energy (caloric) intake."
And of course, this diet, because it is government policy, has been tested—in rigorous, clinical trials funded by the NIH. Indeed, the NIH has spent at least a billion dollars on these trials, on more than 50,000 people altogether.[17] The results were that a diet low in fat with "moderate" carbohydrates does not fight any kind of disease—not heart disease, obesity, type 2 diabetes, or any type of cancer—and does not reduce mortality.
WOW!!!!!!!!!!!!!
Every one posted that 50 years ago we were not obese or fatty. So, if I understand history of obesity correctly, it started back in 1970s when Dietary Goals were established. Sorry people, at that time I was already born and I was born diabetic. I am diabetic type 2.  Nether my perfect fit in 1970, ether my obesity in 2018 let me be free of diabetes. But with Insulin in injections I this Diabetes type 2 reverse started. I can see now how wight my teeth. My nails no longer yellow and rough. My skin is smooth and no dry. So, no any diet do the job to reverse diabetes, but Insulin does. It is also reduce mortality, and prolong life of diabetics. In statistic it is one out of ten Americans. Good job I will say.
Doctors have been prescribing the government's low-fat, high-carbohydrate diets for decades now, and Americans have largely complied.Why do I need low carb diet Yet, we have not seen better health. Should we abandon promising new approaches backed by rigorous science in favor of weak, speculative data? The answer for an evidence-based clinical practice seems clear.
Now I really lost. Why do I need low carb diet? Low fat is good for me, I do not eat fat or oil, or batter, any food with this products. High carbs diet is OK, and it is MD recommended, right? All time when I read this article I was sure it was all about how low carb diet is good for health. And not the conclusion is right opposite.
I am too lazy person. I do not want to read it another time. As I said, do not let your brain be washed, does not matter by whom, MD or politics. They all start with Low carb, and finish with High carb, but we need just what is right for us.

The Latest Attack on Low-Carb Diets: Science or Politics?
by Nina E. Teicholz, MPhil; Fabiano M. Serfaty, MD
 https://www.medscape.com/viewarticle/901910?nlid=125148_381&src=WNL_mdplsnews_180921_mscpedit_wir&uac=164666HZ&spon=17&impID=1745938&faf=1#vp_1


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Thursday 20 September 2018

Low Carb, High Carb, Bad Carb: How Much is Best? By Kathleen Doheny

While researchers continue to sort out exactly how many of our daily calories should come from carbs, experts say most of us could use a bit more information on carbohydrates, starting with: What exactly is a carb?
Really, what is "carb"?
How count amount of carbs I can eat?
When it is "low"?
When it is "high"?
I do have book in my hands.
"The Drinking Man's Diet or How to Lose Weight with A Minimum of Will Power" by Gardner Jameson and Elliot Welliams.
Published in 1964 Cameron & Co. San Francisco.
So, what is a carbohydrate" Mostly, as you will learn in this book, carbohydrates are concentrated in starches & sugars. They are almost absenr from "man-type" foods like meat. fish, cheese, and salads....."
Really very interesting. Who are authors of this so lovely diet? Does not matter. We do have a lot of diets published by MD and Pro in food industry. What makes them to be experts? Nothing. Just read testimonies, and .... of cause one must trust in them, and in authors. I am not one who is easy to trust. At first I took a look at the diet, what I may eat in attempt to lost 9Lbs in 30 days, or any X lbs in any Y days.
Breakfast:
1/4 cantaloupe or 4Oz of tomato juice: 5 calories.
ham or bacon - 2 slices                          0 carb.
egg                                                          trace
coffee or tea with cream                         0 carb.
Lancheon:
Dry Martini or Whiskey with water or soda         0 carb
Boiled fish or steak or roast chicken                     0 carb
2 glasses dry wine    if you wish                           1 carb
green beans or asparagus (1/2 milk)                     4 carb
lettuce & tomato salad                                          4 carb
coffee or tea.
Dinner:
martinies or highballs                                          0 carb
shrimp coctail                                                      4 carb
beef, pork, lamb, chicken or turkey                    0 carbs
green beans                                                         6 carb
2 glasses of dry wine                                          1 carb

1/2 avocado with dressing                                  8 carb
cheese                                                                   trace
 coffee or tea                                                        0 carb
Brandy                                                                 0 carb
                                                   total 37 + carb.
Because of  1 carb= 4 cal. Total 37 * 4 = less then 160 cal.
Where that diet come from? Authors said, they took this diet from their friends who are pilots. Pilots must be fit, and at the same time they cannot use starvation diet. Interesting, can they be addicts? Authors did not say that.
       There are thousands of recipes published how to lose weight. There are not less books published. And for every one of us there are there are Rx from MD every time we go to clinic how to eat and what to eat. It is really easy to be lost to whom to follow.  Do MD know what Rx he put in my hands and how this treatment will work for me? Not at all.
Carbohydrate studies are plentiful, but agreement about the best way to eat carbs -- and how much of them we need on a daily basis -- is rare.
Really interesting. It is not only how much we need to eat, but what do we need to eat, or what we need do not eat, in spite of all published studies, not clear and even absolutely not reliable. 
But another recent study by Harvard researchers found a higher chance of premature death in both low-carb eaters and high-carb eaters.
WOW!!!!!!!!!!!!!!!
The newest study, presented at a meeting of European cardiologists in August, looked at a U.S. sample of nearly 25,000 people. It found that the low-carb eaters had a 32% higher chance of dying from any cause during a follow-up of over 6 years. The risk of death from heart disease, when looked at separately, was 51% higher, stroke, 50%, and cancer, 35%. They evaluated other studies to confirm their findings.
Really, be very careful to trust in any studies.
       So, what to eat? How much to eat? And what do not eat?
Why someone must to say me, how to live my life? I do know how to do my job. I do know how to bring up my children. I do know a lot. Why do not I know how to eat right? I do know it very well. There are some rules I have to follow in my daily life, and I have to follow them day after day.
      Budget. Regardless of what is good or bad, I can buy only what I do have money to buy. This include food and medicine and many other staff for my household. So, even I do know that organic food is better then processed food, I buy what I do have on market, and as best price as I am able to find.
     Processed food vs homemade food. I do know that at home I am able to cook better food then to buy in McDonald. Do I buy food in McDonald? Yes, I do. I cannot all the time have what is best. We have meal outside everyday. We do not have time to cook as we wish. And there are many other abstractions why we have to eat what we do, even we do know there are better way. We simple do not have the path for this highway.
     Health issue. I do know that I have complicated liver. I cannot eat what I love to eat. I cannot eat oily food, fat food, or batter. There are many other complications in my health. So, even I do love some meal, I have to avoid it. As it is in the diet I posted above. I like to take 2 glasses of dry wine, but I cannot. I do suffer from headaches all my life. I cannot drink ether red nether dry wine, Whiskey, or dry Martini.
      Preferences and limitations has everyone of us, and there is nothing we can do, but respect who we are and follow our own rules and limitations. If we do know that, able to follow the way we do, then say me, why we do not live right? Who is able to show to me way to live my life?
"You don't know if it's a select group of individuals who chose to go on a low-carb diet for health reasons," for instance, says Alice Lichtenstein, Gershoff professor of nutrition science and policy at Tufts University's Jean Mayer USDA Human Nutrition Research Center on Aging.
You must be kidding, yes? There are no person choice to follow low carb diet. BTW, are you sure that any person follow low carnb diet? I familiar with one person who used to live on this diet. It was Elizabeth Hughes Gossett, diabetic who first in America started to take insulin.
Elizabeth was 4 feet 11.5 inches (1.511 m) and 75 pounds (34 kg) when she developed diabetes (at age 11 in 1918). Under diets that averaged 800 calories per day, her weight fell to 45 pounds (20 kg) by August 1922.
 In America people who pretend they are on low carb diet, have body weight over 200 and even 300 pounds. Elizabeth was slow dying at the time when Insulin was discovered by Dr. Banting. With Insulin she started to recover and lived till 1981. So, to say that low carb diet is for healthy reason then say me, what reason is it? Diabetes? Not at all. It did not help Elizabeth, the same way it did not help to million of other American diabetics.
      Low carb diet help to develop high income buy talking about diet, and providing dieting recommendations. There are no one benefit for those who follow it. Just timeless Death of any cause. Still every time I am in Clinic MD said, I have to lose weight, and Rx low carb, low fat, low sugar, low calorie diet. I am obese person now. I used to be naive and I followed MD orders. This is the way to collect more pounds then any medical condition will let to do. Right now I am no longer naive. I simple eat what is good for me, even pound of grape at once. MD recommended just 18 grapes per day. What about weight? It is stable now. I take Insulin, Lantus Solo Star, and I do control blood sugar with Insulin. Weight does not go up. Still, it is high. I do have high water retention. My kidney effected by long standing diabetes, and water stay in body. I do not take any diuretics. In stead I take a lot of water. Right opposite what MD usually recommended to me.
Previous studies have produced conflicting findings. Some have found that low-carb diets promote weight loss and can help heart health. But other studies have found that low-carb eating could boost the risk of heart disease, cancer, and earlier death.
This is important statement about all diets and any studies. Just do not take it for granted that studies done to help you. No. It is all about money, and we are the source of money. Our health, lives, and even deaths are money in American money business. Some business collect money to provide health, other businesses collect money by introducing bad habits and pretend it is good for health. How to find what is best? Simple, do not let your brain to be washed. Keep it clean for own use.


Low Carb, High Carb, Bad Carb: How Much is Best?
 By Kathleen Doheny
https://www.webmd.com/diet/news/20180907/low-carb-high-carb-bad-carb-how-much-is-best?ecd=wnl_hyp_092018&ctr=wnl-hyp-092018_nsl-ld-stry_1&mb=PhVlaTw1CBS1ZMU%2fTqByPuHnVev1imbCu5O66y7JnDg%3d


via Ravenvoron

Back to Insulin One


A change in insurance has led to a change in insulin.

We've used up our stash of Novolog, and the first cartridge of Humalog in several years went in the pump 3 days before back to school.

Some people say they experience no difference at all between the two insulins. Some think Novolog withstands heat better. Maybe Humalog sticks around in the system longer. Humalog could be more likely to clog infusion sets. We switched to Novolog a few years ago because it was reported to kick in just a little bit faster. Some of the differences are detailed here, on T1D Living.

The key difference to us is that insurance will pay for Humalog now, and it won't pay for Novolog anymore.

There are too many variables here for this switch to serve as a scientific experiment. The change coincided with an already established need to make some pump setting adjustments. It also coincided with back-to-school, and with the hamster wheel which is marching band season. A couple of things do seem obviously different, despite the chaos.

What we've noticed for sure is a greater need to pre-bolus breakfast. That aspect feels familiar to me from our switch from Humalog to Novolog a few years ago. Breakfast, after which my daughter's bg had spiked significantly almost every day since diagnosis, became more manageable with Novolog. The Humalog is a little more sluggish.

I'd also agree that Humalog sticks around a little longer. It's hard to see during the day, but I'm noticing that the Dexcom graph's downward slope continues longer on the last-before-bed bolus, or for any overnight corrections.

Because we're changing basal rates anyway, based both on feedback from our last endo appointment, and on the schedule changes from the start of school, it's hard to tell what other differences there are. It won't be until we finish tweaking that we can see, for example, if the total daily dose went up.

Given my druthers, I'd say Novolog is probably a snappier, cleaner variety of insulin, and that it would be nice to go back. But in accounting for Humalog's more sluggish nature we're making adjustments that are working.

Humalog and NPH were the first insulins prescribed when my daughter was diagnosed. The glass-half-full part of me will note that Humalog's challenges are minor and manageable compared to the nightmare that was NPH.





via Adventures in Diabetes Parenting

Tuesday 18 September 2018

The Edgpark Order that Won't Die


We placed our initial Edgepark order in March. The details of that ordeal are here, if you'd like to read the beginning of this story.

I returned two of the three items in that shipment on April 11th, using the return label sent to me by Edgepark, because they were not items my daughter uses, nor were they the items prescribed.

I subsequently received a bill for the Verio Test strips I'd returned. When I called, the representative said to disregard the bill. Edgepark was in the process of 'billing the return' with our insurance.

Ignore it I did, along with a couple of subsequent, identical bills I received in quick succession.

Mid-summer, after another bill, I called and was told again to disregard it.

Fast forward to the beginning of this month. I placed an order for a new Dexcom G6 system.

I then received an email telling me I had an outstanding bill. I called and was told once again to disregard it.

Two weeks later, I followed up, since there'd been no word on the G6. They'd just processed the order with the doctor's prescription, I was told, and it would be shipping from the Ohio warehouse within 24 hours. It would be at my house by Friday via FedEx. It was very specific information.

I then received another bill, for a higher amount than the previous ones, and a subsequent email warning me that no further orders would ship until I had resolved my delinquent account with the Edgepark billing department.

So I called. Yes, I was told, they had 'billed the return' and refunded my account $63.60 for the test strips. I acknowledged that as a good start, but then noted that I had paid them $288, and that they were now sending me bills for over $400. It was an unproductive conversation which ended in the representative telling me she was sending March's whole order and subsequent billing back for a 'full review.'

So, did that mean my upcoming order would be cleared to ship? "Oh- yes - that wouldn't have been on hold anyway."

Today, still no word on the Dexcom, so I went onto the patient portal to check the status. There were 'urgent alerts' posted warning me that no further orders could be processed until I paid my outstanding bill of what was now two hundred-something dollars.

An hour phone call, piles of explanation-of-benefits and bills reviewed, and lots of math later I agreed with the billing representative that the current number was correct. In (very) short, the original billing on the one item I did keep (Dexcom G4 sensors) was also incorrect, not in my favor, and that error was reflected on a subsequent explanation of benefits in July. After the whole day's bills were sent back for review, my account was credited with the rest of the Verio money Edgepark owed me, in order to pay for part of the cost of the Dexcom sensors. I still owed the balance for those supplies.

I paid the bill then and there on the phone.

My daughter's Dexcom G6, the third person in so many weeks told me, is on its way. She's, once again, really looking forward to getting it. It seems highly unlikely to me that there isn't at least one more phone call involved in this. And then, of course, the next set of bills...

Stay tuned.

And if you have a choice to get supplies from someone other than Edgepark, do.




via Adventures in Diabetes Parenting

Types of diabetes and why it is important to understand. September 18, 2018

A new study finds that type 2 diabetes remains overwhelmingly the most common type of diabetes diagnosed in American adults who have the disease. The study found that among Americans who are diagnosed with diabetes, 91.2 percent have type 2 diabetes and 5.6 percent have type 1 diabetes.
 https://www.sciencedaily.com/releases/2018/09/180917191843.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine%2Fdiabetes+%28Diabetes+News+--+ScienceDaily%29
Why it is so big gap between %%% of types of diabetes? One way is that diabetes is not really the medical condition but rather choice of person to live the style one choose. This is why so many type 2 diabetics and so little in %%% diabetics type 1. Another way, it is how this study were conducted? Maybe there is something wrong with studies so the result of studies cannot be reliable.
 The study is based on data gathered by the CDC's National Health Interview Survey (NHIS), which is conducted annually by survey-takers who visit peoples' homes and ask them about their health. Bao says the NHIS is the first and only national health survey that attempts to determine how many adults have each type of diabetes. Since 2016, survey takers started to ask respondents who had been diagnosed with diabetes if they had type 1, type 2, or other type.
WOW!!!!!!!!!!!!!!!
       You must be kidding, yes? How these data can be considered as studies?  The surway-takers asked diabetic what type of diabetes they do have, and no one of us can say how we were diagnosed with type of diabetes we were diagnosed. Really, how diabetic can answer what type of diabetes we do have? Simple. If we do have diagnosed diabetes then we do know our diagnose, type 2 or type 1. For this reason it was much easy to go to clinics and take study of patients' files. In home to home survey what data can be collected?
       One will say: "I am diabetic type 2. I control blood sugar with proper diet and work out four times a week. No medicine. Only life style modifications."
       Another way: diabetic will say what medicine one takes, and there is no insulin in medical box. So, one is diabetic type 2, insulin resistant type of diabetes. No one diabetic can say what degree of resistance one do have. No one even able to say what really does it mean and how it looks like to be resistant to insulin. Really, what is this diagnose about? According to Dr. E. Joslin, resistance on insulin when usual dose of insulin does not control blood sugar level and much higher dose of insulin needed. But this diabetic does not take insulin at all. How one can possible know if one resistant to insulin or insulin dependent? Diabetic takes medicine according to MD Rx. So, medical box include SU, medicine which increase insulin secretion, but naive diabetic has no one idea what this medicine about and why it is so hard to take it.
       At least but not last, why it is only two types of diabetes were considered? Why there is no LADA in investigation?

       Does not this survey sound anything but study? Who they are, survey-takers? They are probably students who worked for collected data for professor. Professor presented student's work as its own, and got credits in sum of $$$$ or any other beneficial way.
       At first, why these studies were conducted? 
Study lead author Wei Bao, assistant professor of epidemiology in the College of Public Health, says the results are important because it allows health care professionals and policy makers to better allocate resources to treat each type of the disease.
      If so then studies must be as reliable as it can be. But there is no  the case. If diagnose was wrong then answer would be wrong. Also there is no any prove that diabetic really diabetic if one can treat diabetes with life style medications. Say me, what is difference between diabetic type 2 who control diabetes with diet and work out and healthy non diabetic who simple do not pretend to be one? It is self-reported data. This survey has nothing important to present, just to show, how effective diabetics can be exploited and abused. It also makes author to feel himself to be an important personality. Why not? every one can treat diabetics type 2. This is why now it is not epidemic but pandemic already. The more of us then is better.
       There is no one problem to diagnose of diabetes type 2. It is only bathroom scale and glucose meter strip. So, when diabetes type 2 was diagnosed, or even with normal level of sugar it was presented that MD has diabetic type 2, the treatment is safe for MD. No one will say that Rx was wrong. How Rx to healthy life style can be wrong? No one way for that. But MD has a patient, Diabetic type 2, and money will be flooded. More diabetics type 2, more money for studies and MD.
Type 2 diabetes mostly develops in adulthood and is caused by a complex interplay between genetic and environmental factors such as obesity, unhealthy diet and physical inactivity. Type 2 diabetes is treated with lifestyle change, medication, and/or insulin.
       This part of article is most interesting. How diabetic can say  what type of diabetes one has?If one takes insulin then what type of diabetes is it? If one is diabetic type 2 who takes insulin to control blood sugar out of mortality level, then is this diabetic type 2 insulin dependent? Not at all. It is Insulin Resistant Insulin Independent diabetic type 2. This medical conditions happened because of life style diabetic live.
 Type 1 diabetes is an auto-immune disease that typically develops in childhood. Patients with type 1 diabetes also have problems in producing insulin, and therefore they require insulin treatment for survival.
  Does professor know the subject of discussion? He does, but only in one way, Self-benefits. It could be money or some credits, or recognition in network, anyway there is nothing in science or study. For professor's understanding, auto-immune disease the reason why insulin secretion is low. So, there is no way it can be :"Patients with type 1 diabetes also have problems in producing insulin ..... ."
       This is why diabetics type 1 need insulin in injections. The question is, why insulin is the part of diabetics type 2 treatment? Because of many MD right now prefer to Rx insulin for type 2 diabetics, even without any changing in diagnose. Simple, they Rx insulin, and this is how diabetics type 2 may have  insulin-dependent insulin-resistant non-sugary type of diabetes. Sound absurd, but in medicine there is no such things as "absurd" and anything what MD said is true, and only true, and only one true.
"Type 2 diabetes can be prevented through lifestyle changes, but so far, there is no established method for preventing type 1 diabetes," Bao says.
       This part is most popular in every study by everyone, Old Farm Housewives  including. Is there are something new? Never. When consumption swept one million of victim after another, the absurd was more rude. Victims' bodies were not allow to be graved as those who were not effected by Consumption (TB in present time). In hospitals they were kept in wards and all windows were closed to avoid fresh air. Why there are no method to prevent diabetes type 1? Because of diabetes cannot be prevented, but it must be treated. So, the amount of diabetics must be present. This is why it is types of diabetes. One type, type 1 diabetes, can be treated and even cured with insulin injections right regime. Another type, type 2 diabetes, can be prevented, treated, reversed, by million of Med Pro. Would this type of diabetes ever cured? Of cause not. It is well established business. Every one can treat diabetics type 2. Just provide Barking Therapy, and collect %%%%. Simple and very profitable.
Bao emphasizes the need to continue monitoring the dynamic changes of these two types of diabetes in American population. He expects more Americans to report type 2 diabetes as a result of the ongoing obesity epidemic. But he also wouldn't be surprised if more adults have type 1 diabetes because of improved treatments that keep patients alive longer.
      If so, then why do not try this treatment to  provide for all diabetics without consideration if type of it? Right now diabetes type 2 is number 7 cause of death in America. It is number 4 cause of Death in NYC. But if in stead to Rx life style modifications diabetic type 2 would have Rx to insulin in injections, right after being diagnosed with diabetes any type of it, maybe our lives would not be cut timelessly?
"Type 1 diabetes used to be lethal for children years ago and so children who had the disease had shorter lifespans," he says. "Now, treatment has been improved to be so effective that a lot of children will survive well into adulthood."
       When it used to be that diabetes type 1 was lethal for children? It was hundred years ago, before Dr. Banting developed Insulin and found the cause of diabetes. Those children who were treated with insulin in injections  still alive. They are type 1 diabetics because of they take insulin for survival. In contrary, diabetics type 2 do not have Rx to insulin, and we die less then 10 years after being diagnosed with diabetes type 2 and treatment started.
       Because of I am diabetic type 2, I do have my own study, and my own hypothesis. What if insulin taken early will decrease and stop diabetes type 2 epidemic, pandemic, or any name of it? Is this possible to be happened? No way!!!!!!!!!!!!!!!!! There are a lot of money in this business right now. And most important, we are not danger for society. No one can get diabetes type 2 from diabetic type 2. It is inside of us, and it stay with us, alive or not, regardless of lifestyle and diet,  and any wrong treatment of it just cut short our lives.

Current rates of diagnosed type 1 and type 2 diabetes in American adults
by  University of Iowa
September 17, 2018


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