Sub-types for type 2 diabetes. September 23, 2018

Most patients diagnosed with type 2 diabetes are treated with a "one-size-fits-all" protocol that is not tailored to each person's physiology and may leave many cases inadequately managed. A new study by scientists at the Broad Institute of MIT and Harvard and Massachusetts General Hospital (MGH) indicates that inherited genetic changes may underlie the variability observed among patients in the clinic, with several pathophysiological processes potentially leading to high blood sugar and its resulting consequences.

Very promising introduction.  What do they suggest?

The work represents a first step toward using genetics to identify subtypes of type 2 diabetes, which could help physicians prescribe interventions aimed at the cause of the disease, rather than just the symptoms.

         There are one out of then Americans who is diabetic. 95% of Diabetics population are diabetics type 2. How many diabetics type 2 will die till treatment, even if it will be found according to the new studies, will available for common diabetics? In present time diabetes is number 7 cause of Death in America. Also, according to Med Pro publications, Diabetics type 2 die withing 10 years after being diagnosed with diabetes due to all - cause Death, if they do not start to take Insulin in injections. If they do, and Insulin Therapy is is right regime in right dose, they survive, and will start to recovery. If they do not, complications will be collected, and Death due to heart attack, or stroke, or cancer, or any other medical complications, will follow.
       So, study identified sub-types of diabetes type 2. I did not get how many still, it is diabetes type 2, and this medical condition still be treated with all available Junk Medicine but not with Insulin. One after another a new medicine enter to the market. The number diabetics type 2 who dies every year getting higher and higher.This fact raised a very reasonable question.
 If diabetes identified by level of sugaar in blood, and level of sugar in blood run from 100 mg/dl to over 1000 mg/dl, is this possible that there are only one stage in diabetes type 2 development?
       Not at all. Studies which were done by some group in IUC identified that then higher level of sugar in blood then less chance diabetic will survive.Then higher level of sugar in blood then more complications diabetic type 2 does have. So, according to that studies, the level of sugar in blood play most significant role in Diabetes survival and well being. If take this level of sugar in blood and body mass it will be also very visible that level of sugar is higher in obese diabetics, and body mass less in those diabetics who has less sugar in blood.
      How many types of diabetes?
Type 1, type 2, Type 1.5 (LADA), Mody, Idiopathic diabetes, gestational diabetes, pre-diabetes, non-sugary diabetes, sugary diabetes, insulin-dependent diabetes, insulin resistant diabetes, insulin independent insulin-resistant diabetes, and list go on and on.
Now in addition to this list types of diabetes another division was identified, sub-types of diabetes type 2, not type 1, but sub - types of diabetes type 2.
        It is understandable that type 1 diabetics are very angry. It looks for them that type 2 diabetics got all attention, and they are, type 1 diabetics, got nothing. The point in it is only one. Type 1 diabetes still on the list of diagnose. This is why only 5% of all diabetic population, millions of us, diagnosed with type 1 diabetes. LADA, MODY and all other types of diabetes fill into 5% of diabetic population. 95% of diabetic population is type 2 diabetics. This population needs to be treated. We live in constant pain, in suffering and everyday fear that we are getting worse. In contrary with type 1 population who take insulin, and health getting better, no complications, no obesity, no humiliation. We are guinea pigs for costly medical studies.

It's known that type 2 diabetes can be broadly grouped into cases driven either by the inability of pancreatic beta cells to make enough insulin, known as insulin deficiency, or by the inability of liver, muscle or fat tissues to use insulin properly, known as insulin resistance.

The first question to this statement, how do you know it? Is there are studies were done what is insulin resistance and when it is insulin deficiency? Never. No one studies like that. To run these studies level of insulin needed for daily activity must be identified. What is this level? No one publication in this direction. No one every studied how much insulin human body use in normal daily life. The same about insulin secretion by every one human body. No one ever tested what is the level of insulin secretion does diabetic type 2 pancreas. In modern time there is no any technology available to do studies like that. So, the statement on which all studies are based is fake. What is possible to say about study? It is fake study. Nothing more what can be said. There are no foundation under this building. With first argument it fall apart.
      Still I love the part that sub-types of diabetes type 2 identified. BTW, how many sub-types of diabetes type 2 was identified? I lost in reading. Anyway, in stead of study and create a new types for one medical condition why do top identify stages of this medical condition? There are different treatment for flu and pneumonia, for stage 1 kidney failure and stage 4 kidney failure, and so so on. Why diabetes is only one stage? It is long, really very very long way to walk from 100 mg/dl to 770 mg?dl, from A1c5% to A1c 12.4 %. So, why to not identify stages of diabetes and according to stages of diabetes develop standards what dose of insulin diabetic type 2 need to recovery?


Genomic study brings us closer to precision medicine for type 2 diabetes.Really?
by: Broad Institute of MIT and Harvard
https://www.sciencedaily.com/releases/2018/09/180921151441.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine%2Fdiabetes+%28Diabetes+News+--+ScienceDaily%29
 

via Ravenvoron