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Tuesday, 25 September 2018

A New Reason to Be Wary of SGLT2s September 25, 2018

There are reports of a rare but serious bacterial infection in patients taking common SGLT2 inhibitors for diabetes. In response, the US Food and Drug Administration (FDA) issued a warning about necrotizing fasciitis of the perineum, also known as Fournier gangrene.
Symptoms of the infection begin as early as 1 week and as late as 2 years after starting the drug. Out of 12 case reports to the FDA, seven were men and five were women, ranging from 38 to 78 years of age. All 12 patients were hospitalized and required surgical debridement. Four patients developed serious systemic complications, including septic shock, and one patient died.
There are some responds to this article. I cannot post my response because of I am not Med Pro. They do not take responses of patients. o, I post it here, on my blog
 But virtually all diabetes meds that are not Metformin or insulin have massive side effects.
Insulin does not have side effects. The hypoglycemia is  not side effect but normal healing process. No one medical condition heals by steady down. It is all the time up - and - own. With time with Insulin Therapy high blood sugar getting lower. and low blood sugar does not drop to fatally low level. In diabetes type 2 this process takes years to recovery, many ups and downs. Still, it is not side effect of Insulin. It is how our human body survive, The same as with developing very high level of sugar it is getting up and down. But in the case of developing highest level getting higher and does not go down.
      It is right opposite with Metformin. Metformin has very severe side effects. And most important  part, it does not have healing abilities. Try to stop to take metformin and see, what happen with level of sugar. In case of Insulin sugar will go up right away, next day meter show that diabetic forgot to take shot. Metformin, in contrary does not effect level of sugar. Usually med pro insist that Metformin must be built in system before it will start to work. Still, side effect, poison effect, diabetic develop with first tablets one had swallowed.
All meds, vitamins, herbs, and supplements have up and down sides. HRS, MD, FACC
That's true.As I just pointed out above, the side effect and healing effects are not the same, even when day looks alike. Also when Death considered as side effect I am better to avoid this medicine and be with my pain and discomfort rather then be in coffin.
    Now, back to Invocana. This medicine was launched in 2014, as I d remember. Probably I am not correct. Now it is 2018. 4 years, and it is already so many warring. Diabetes type 2 is progressive disease. This means that it will not be cured in soon future, but it will accompany victim and get victim worse. What diabetes will do in incoming future? For how long this medicine can be taken? Also sugar in urine is one of sings of diabetes. How progress of healing would be measured or tested?
The drugs to be aware of include canagliflozin, empagliflozin, dapagliflozin, and ertugliflozin. These drugs are prescribed to 1.7 million people in the United States. The more common side effects are yeast infections, urinary tract infections, and low blood glucose when taken with other diabetes medication
 So, low blood sugar only when Invocana takken with other diabetes medication. If there is no low blood sugar then there is no healing. It is another diabetes medicine which give healing such as Insulin. So, why take Invocana in first place? Just why diabetic needs to take this so danger drag? Just take Insulin without Invocana, and there are no side effect left, just long road to recovery.
Patients taking SGLT2 inhibitors should now be counseled about the risk for necrotizing fasciitis in the genital and rectal areas, and assessed for signs and symptoms of infection. If suspected, stop the drug and start treatment immediately with antibiotics and surgical evaluation. Confirmed infections should be reported to the FDA.
Thank you so much, but I am better to say ?no? to Invocana, inject Lantus Solo Star, and do not need any surgery at all. I love my way must better.

A New Reason to Be Wary of SGLT2s  Arefa Cassoobhoy, MD, MPH
by Arefa Cassoobhoy, MD, MPH
https://www.medscape.com/viewarticle/901880?nlid=125169_1521&src=WNL_mdplsfeat_180925_mscpedit_wir&uac=164666HZ&spon=17&impID=1749492&faf=1

see also:
 Invokana Side Effects   http://www.ravenvoron.net/2014/08/invokana-side-effects.html

Invocana Deadly March  http://www.ravenvoron.net/2014/05/invocana-deadly-march.html

Invokana- Perfect Cure For Diabetics Type 2  http://www.ravenvoron.net/2014/02/invokana-perfect-cure-for-diabetics.html

 Invokana To Treat Diabetes Type 2 http://www.ravenvoron.net/2014/02/invokana-to-treat-diabetes-type-2.html


via Ravenvoron

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