Diabetes type 2, Honey and Empagliflozin. March 20, 2018

Now a study has found that empagliflozin, a newer treatment for type 2 diabetes, reduces liver fat in patients with NAFLD and diabetes.
 Diabetes medicine reduces liver fat in nonalcoholic fatty liver disease

Source: The Endocrine Society

https://www.sciencedaily.com/releases/2018/03/180319124242.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine%2Fdiabetes+%28Diabetes+News+--+ScienceDaily%29

 Trade name: Jardiance 
Generic name: Empagliflozin 
Drug class: SGLT2 inhibitors 
Manafacturer: Boehringer Ingelheim and Lilly Diabetes
So, why it is  Empagliflozin  which is so effective for diabetic's type 2 liver, and not other members of the same family such as Invocana? They all all the same, they reduce level of sugar in blood by sending sugar into urine and get it discharged by diabetic's type 2 already ill and heavily effected by diabetes, kidney.

"Despite the fact that NASH may progress to cirrhosis of the liver and liver cancer, there are no approved medications for treating NASH or NAFLD, and agents like metformin, pioglitazone and vitamin E have had limited success in reducing liver fat," Mithal said. "Our results suggest that empagliflozin may help in treating NAFLD."

      At first, why Metformin suppose to heal or treat diabetic's type 2 liver? How it works, really? Metforming is medicine developed to stop liver, healthy liver, to release sugar into blood stream between meals. This is how any healthy body system works. We do not eat without stopping. We eat, and then part of the meal kept into storage for the future use. Metformin brake this healthy way, and effect liver to stop to do job in the way as it must do. Now it is presented that Metformin is medication to treat liver?  Why there is surprise why this medication did not stop progress of liver to develop liver cancer? It is just logical way to go.
     pioglitazone. The mechanism of action is about the same as Metformin. It is also work in liver to reduce release of glucose into bloodstream.
  Finally, Vitamins E. Since when this medicine used to treat diabetes or liver? It is supplement, not medicine at all.

To treat liver it is one medicine is very very popular, Nexium. It is not only popular, but also very effective so far. Nexium is brand name. I do take brand medicine for liver, so I do not remember generic medicine name. I take this medicine more then 10 years by now. Every day 40 mg. never miss.This medidine keeps my liver OK by now.

The study, funded by the Endocrine and Diabetes Foundation India in New Delhi, included 50 patients who were 40 years or older and had type 2 diabetes and NAFLD. The patients were randomly assigned to receive empagliflozin (10 milligrams per day) plus their standard medical treatment for type 2 diabetes, such as metformin and/or insulin, or to receive only their standard treatment without empagliflozin (control group). All patients were aware of their group assignment.
At the beginning of the study and 20 weeks later, the patients had blood tests of their liver enzyme levels, which are typically elevated in NAFLD. They also underwent measurement of their liver fat using a new, robust technique called magnetic resonance imaging (MRI)-derived proton density fat fraction.
After 20 weeks of treatment, the liver fat of patients receiving empagliflozin decreased from an average of 16.2 to 11.3 percent, whereas the control group had only a decrease from 16.4 to 15.6 percent, a statistically significant difference between groups, the researchers reported.

 WOW! So interesting! I do remember since my childhood that humor: one very bitter berry Kalina was proud that it was very good to eat with Honey. In response Honey said: And I am Kalina without you very good.
 So, not we do have:
metformin +Empagliflozin

(metformin and insulin) + Empagliflozin
 insulin + Empagliflozin
The question is, in which group fat decreased by 11.3%

 Where is the Honey?
What is Kalina?
Do they have Honor? Does study looks decent? Not for me.

By removing excessive glucose from the body through urine, Jardiance helps to improve glycemic control among patients with type 2 diabetes. This can result in improved HbA1c levels, which can reduce the risk of diabetes-related complications.

I am sorry, Endocrean Society. When there are too much sugar go into urine, kidney fail.  Waater skip through skin. It leads to infection, and wounds development which is not possible to heal. Amputation only the choice. If diabetic type 2 did not find another way to keep limbs.

via Ravenvoron