Investigators tested 154 non-diabetic PD patients for fasting blood sugar and insulin to assess the prevalence of insulin resistance and to correlate insulin resistance with other metabolic indicators, motor and non-motor symptoms of PD, and quality of life. Based a widely used formula, known as the HOMA index, they determined how many of these patients had a reduced response to their own insulin. Among other measurements, their weight and height were recorded and their movement and cognitive performance were measured.So, if so many patients with PD have insulin resistance and not dianosed with this condition, then what about many other patents who are chronically ill? Do they have insulin sesistance or not?
https://www.sciencedaily.com/releases/2018/08/180802151525.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+scie
ncedaily%2Fhealth_medicine%2Fdiabetes+%28Diabetes+News+--+ScienceDaily%29
Healthy Range: 1.0 (0.5–1.4)
Less than 1.0 means you are insulin-sensitive which is optimal.
Above 1.9 indicates early insulin resistance.
Above 2.9 indicates significant insulin resistance.
HOMA-IR Blood Code Calculation
X=
Second, fasting glucose level. Sorry, what is this? If it is healthy person then it is about the same level every morning. What about me, diabetic type 2, insulin resistant type of diabetes? OK, today it is 54 mg/dl.
(2 * 54) : 405 = 0.26666 Looks like I do not have insulin resistance.
There is the trick.
Level of my own insulin secretion is the same day after day. It is 2.
index, 405 is the same for every one of us, regardless of level of sugar or insulin resistance.
The level of fasting sugar is different for every one of us, and it is different one day from another.
If fasting sugar is 370 mg/dl?
(2*370) : 405 = 1.83
I was diagnosed with 370 mg/dl in blood. So, it was early insulin resistance. (According to presentation).
My sugar was higher then 599, meter said, (high, see doctor) after this number. Now what was insulin sensitivity or insulin resistance?
(2* 599) : 405 = 2.95. High insulin resistance.
Now take a look at the all those numbers. Is this really true that my level of insulin secretion so high to be insulin resistant? Not at all. It is optimal.
If so then why sugar is so high?The answer is only one, the level of insulin is not optimal. This formula show that only one way to decrease level of sugar in blood is, to add insulin.
(400 units ( my daily dose ) * 54 mg/dl ) :405 = 53.53 WOW!!!!!!!!! Really what is it?
As I do remember from my high school studies, there are not only numbers, but measurment must be in count.
HOMA - IR = A, just coefficient, no any measurment. But we cannot multiply uIU/ml on mg?dl. Both this numbers must be mg/dl or uIU/ml. It is simple math.We cannot multiply
km * kg.
or sec * day.
We have to make day in sec, or sec in day. This is simple math, nothing special about insulin or blood sugar, or any resistance at all.
Really sorry guys. I am sure you count correctly how many Hr you spend to study this crap, and how much you get to be paid. You are perfect in this math. But leave insulin resistance how it is, simple tool to make money. With study like this it is obvious , every one American is Insulin Resistant and entitled to get Invocana. At least every one have to add to Med Pro Profit.
The second and more specific impact is that identifying patients with insulin resistance could allow for personalized medicine, whereby PD patients with insulin resistance may be treated with medications targeted to reverse the condition. Research on the use of diabetic medications for PD, such as GLP-1 agonists like exenatide and liraglutide, is ongoing.
via Ravenvoron
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