Obese mice lose a third of their fat using a natural protein. October 30, 2018

 Obese mice lose a third of their fat using a natural protein

 https://www.sciencedaily.com/releases/2018/10/181029084038.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine%2Fdiabetes+%28Diabetes+News+--+ScienceDaily%29

Obesity, which affects more than 650 million people worldwide, is the major driver for metabolic syndromes, which includes disorders such as insulin resistance, glucose intolerance, hypertension and elevated lipids in the blood.

 Looks like true. We all see on the streets more and more old people who are obese. I am obese, about 400 pounds. So, according to the authors, this is why I am diabetic type 2. My father was not obese. He died at age of 37. At that age I was not obese too. Now I am obese, and I am 66 years old. If I did not have insulin in my ref right now, and if insulin did not come to my medical box back in 2011, right now I would not be 400 pounds. I would be skeleton. This is reality about obesity.This real facts never mentioned. It is only presented that diabetes type 2 resulted by obesity. The fact that right now people with diabetes live longer, simple ignored. Also as it was in long long past, people with diabetes still not diagnosed. Why? It is nothing so difficult to diagnose diabetes, just take reading of glucose level in blood. Good question, why so many people with diabetes still out of diagnose to be diabetics. What our Medical Complex waiting for? More complications. More money. To secure the hook around our neck.

The treatments also reduced a number of obesity-related disorders in the mice, such as hyperglycemia -- excess blood sugar that is often linked to diabetes -- and eliminated the fat in their once fatty livers.

 Please pay attention to this so simple quite. What did it say? There are no definition and no understanding what is diabetes, how diagnose diabetes, how diagnose types of diabetes, type 2 particullarly every one talking about, and so so on. Diagnose of diabetes, according to ADA and WHO based on elevated level of sugar in blood. If sugar is elevated above 128 mg/dl fasting, or over 200 mg/dl random, it is diabetes. Personally I wish to say, at the time of diagnose diabetes is already in full bloom. 128 mg/dl, random, not fasting, is already diabetes. Our medical pro simple ignore this fact and pretend that "it is linked to diabetes". Really, what all that MD with titles and degrees are talking about?
Really, do they understand what they are talking about? At least they must be more careful to publish such absurd.

 The researchers found that this chaperone binds to three FGF proteins (19, 21, and 23) that are involved in the control of metabolism. FGF19 and FGF 21 signaling regulates the storage and use of carbohydrates (sugars) and lipids (fats). FGF23 controls phosphate metabolism.

       OK, now what? It is studies, and studies not all the time can be used in practice. What is in practice? In practice, more then 50 years Metformin is the number one doctor's choice to treat diabetics type 2.  Also, with history of hundred years, it still not known what is diabetes and how it can be diagnosed. Yes, it is progress. Now to diagnose diabetes MD does not ask victim to urinate in forest and look at if ants run to urine. They simple take drop of blood and look at the number on glucose meter. Progress. Now every one of us can diagnose yourself with diabetes. Sill, it is not sugar level what show the diabetes stage. It is level of insulin secretion. This test never ever run.For 100 years there are no studies how to diagnose diabetes. There are even no definition, diabetes, what is it? It is not the problem with metabolism.

 "We found that BP3 exerts a striking contribution to metabolic control," Wellstein says. "When you have more BP3 chaperone available, FGF19 and FGF21 effect is increased through the increase of their signaling. That makes BP3 a strong driver of carbohydrate and lipid metabolism. It's like having a lot more taxis available in New York City to pick up all the people who need a ride."

So pity  poor compare. But Wellstein looks enjoy it. What can I say? He is not so good in publishing papers. At least, he must admit it. Better to do not use what is our of your abilities.
      What really he try to say?

"With metabolism revved up, sugar in the blood, and fat processed in the liver are used for energy and is not stored," Wellstein says. "And warehouses of fat are tapped as well. For example, the job of FGF21 is to control break down of fat, whether it is stored or just eaten."

Sorry, in diabetics type 2 bodies fat stored in belly. Also it is stored in many places around body. Where that expression that fat stored in liver come from? From very limited brain ability. The same as NYC taxi drivers.  Really, what authors try to say? Nothing. It is just show up case. 

While the study results are exciting, additional research is required before BP3 protein can be investigated as a human therapy for metabolic syndromes, he says.

More studies needed. (more money needed. we will investigate all what no one  do need).

 The study, published in Scientific Reports, suggests that the protein FGFBP3 (BP3 for short) might offer novel therapy to reverse disorders associated with metabolic syndrome, such as type 2 diabetes and fatty liver disease.

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Story Source:
Materials provided by Georgetown University Medical Center. Note: Content may be edited for style and length.

Thanks for nothing!!!!!!!!!!!!!!!!!!!!!!!!!!!

via Ravenvoron