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Friday, 11 January 2019

Insulin Ressistance by Joslin's Diabetes Center. January 11, 2019

The person's body may not be producing enough insulin to meet their needs, so some glucose can't get into the cells. Glucose remains in the bloodstream, causing high blood glucose levels. In many cases, the person may actually be producing more insulin than one might reasonably expect that person to need to convert the amount of food they've eaten at a meal into energy. Their pancreas is actually working overtime to produce more insulin because the body's cells are resistant to the effects of insulin. Basically the cells, despite the presence of insulin in the bloodstream, don't become unlocked and don't let enough of the glucose in the blood into the cells.
 https://www.joslin.org/info/what_is_insulin_resistance.html
      So, is there are insulin or there is no insulin in bloodstream is only  "one might reasonably expect" and there are no any evidence to support this claim. All what is clinically supported just the high level of sugar in blood. This high level can be due to insulin absence in the same way as it is pretended to be as it is the resistance to the effect of insulin. At the same time with all respect it is still unclear how it is looks like that cell are resist to effect of insulin? What are the evidence how does it looks like? No any evidence. 
     In all medical publications today Insulin Resistance presented that diabetic's type 2 pancreas work hard to secret more and more insulin, that with time the diabetic's type 2 pancreas eventually stop to secret insulin. When it happened? How it is possible to diagnose that diabetic's pancreas secret insulin, secret too much insulin, or does not secret insulin at all? If I do understand it correctly, when diabetic's type 2 pancreas stop to secret insulin then it is the same condition as it is in diabetes type 1, absence of insulin secretion. So, diabetic type 2 eventually became diabetic type 1. How it is diagnosed? Does diabetic type 2 ever became diabetic type 1? No. Diagnose once stumped stick to victim and regardless of the level of insulin secreted by diabetic's type 2 pancreas diabetic type 2 still type 2, Non Insulin Dependent Diabetic. 
     Is this classification to blame? Or this is something bigger then we can see?
Medications for type 2 diabetes focus on different parts of this insulin-cell interaction to help improve blood glucose control. Some medications stimulate the pancreas to produce more insulin. Others improve how the body uses insulin by working on this insulin resistance.
       Probably there are the answer. Diabetics type 2 are Guinea Pigs, Lab Rats for medical studies.  Also with high mortality of diabetics type 2 there are good reason to spread the net to collect more money for research to find cure for diabetes type 2. Is this possible to find cure for diabetes type 2? Of cause not. There are simple no diabetes type 2, no insulin resistance. There is only Impaired Insulin Secretion more or less. When this secretion is absent the level of sugar going up to highest level which is possible. Then it is coma and death. When insulin secretion is sufficient then there is no elevated level of sugar in bloodstream.
     As I posted day before and as it is well known in medical society Insulin is effective to treat any limits in insulin secretion. It is very effective to treat Insulin Resistance. What about all other medicine developed to treat diabetics type 2? Stimulation of pancreas lead to faster pancreas destroying. It is all medicine class SU, such as Glipizide. Other medicine such as Metformin increase sensitivity to insulin. Is there are insulin in blood stream that diabetic's muscle can use? No. So, in one hand diabetic's type 2 pancreas stimulated to secret more insulin, on another hand the same diabetic's type 2 body stimulated to demand more insulin. What are the consequences? Diabetes type 2 is number 7 cause of death in mortality tables by CDC. 


via Ravenvoron

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