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Friday, 22 February 2019

Pathology of Diabetes. post 1. february 22,2019

FCPD ------Fibro - Calculous Pancreatic Diabetes
FCPD is usually severe. Blood glucose level in the range of 500 - 600 mg/dl is not unusual. Sometimes, however, diabetes can be mild. As with the PDPD variety of MRDM, patients with FCPD  are also believed to show the phenomenon of ketosis resistance. About 80% of FCPD patients require insulin for CONTROL of hyperglycemia. However, the vast majority  of insulin - requiring  patients do not readily become ketosis on withdrawal of insulin. A small percentage however do, and the authors have occasionally seen established ketoacidosis in FCPD patients. at the other end of the spectrum are patients who can be controlled with oral agents and a few even on diet alone. (page 34)
World Book of Diabetes in Practice.
volume 3.
edited by L.F. Krall
Published November 1988
Elsevier
         Interesting, is not it? The diabetes is severe. Level of sugar run from 500 mg/dl and up. But ....  there is no ketosis. So, treatment with insulin is not needed. Oral agents can do the job. Can they?  Now  oral agents such as SU which actually the same as insulin but this insulin secreted by already severely ill diabetic's organ replace insulin. For how long the secretion of insulin would be running? So, regardless is oral agent or injectable insulin, insulin is required to keep diabetic alive and functional. Why do not start with insulin right after diagnose of FCDP made? At least there are 80% of FCDP diabetics in this situation who need insulin, and in large dose.
       Does some one met any one who was diagnosed for FCPD? I do not think so. We all diagnosed with Diabetes type 2, regardless of level of sugar in blood, or any fibrosis wrapped our pancreas. We are all Insulin Independent ketisis resistant diabetics, NIDDM.
        I probably would except it if treatment for diabetes type 2 was the same as for diabetes type 1, insulin. It is not. We are Non Insulin Dependent Diabetics type 2 who need lager dose of insulin.


via Ravenvoron

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