Prenatal Metformin Exposure Linked to Adiposity, Obesity in Children

Prenatal Metformin Exposure Linked to Adiposity, Obesity in Children
By Anne Harding
https://www.medscape.com/viewarticle/908994?src=WNL_infoc_190322_MSCPEDIT_TEMP2&uac=164666HZ&impID=1913995&faf=1 

"This is the first follow-up study on children who were metformin-exposed in utero, compared to placebo. Our study indicates that metformin increases the risk of higher BMI, abdominal fat deposition and obesity in childhood. These findings might be markers of future increased risk of inferior cardio-metabolic health," Dr. Liv Guro Engen Hanem and Dr. Eszter Vanky of the Norwegian University of Science and Technology in Trondheim told Reuters Health in a joint email.

 How children were exposed to metfornin?

Metformin is increasingly being prescribed to pregnant women with PCOS, gestational diabetes and obesity, the two researchers and their colleagues note in The Lancet Child & Adolescent Health, online January 28. But evidence for the drug's efficacy and safety in pregnancy is lacking.

        The same as diagnose of Diabetes type 2 the treatment with metformin just  stick with diabetics, and more and more diabetics will pay ultimate price. Child which is still not born yet, already blamed that too much carbs or too little work out lead this victim of medical greed to diabetes type 2. Never mind that this child ever will have insulin in  injections. Metformin to reduce obesity which will be only medicine for corrupted medical care industry. Blood sugar will go up and up. Obesity will ride up. Loss of mobility, high mortality, high medical bills will always in need. In present time if left untreated diabetics type 2 live to up to 50 years. When treatment diabetes type 2 started, regardless of age diabetic type 2 gone less then within 10 years. Children will not survive 10 years.
       What is PCOS? It is fibrosis of ovarian, one or both. It is treatable. Not with Metformin but with surgery. All fibrosis can be cleaned up, ovarian will left free of fibrosis, and with proper treatment with low dose of insulin woman will recovery, get pregnant, and delivery healthy full term baby. At the same time with PCOS fibrosis probably attacked pancreas. The cause of fibrosis is still unknown. The  secretion of insulin getting more limited. The treatment with insulin injections at that time is not so expensive, and dose of insulin is not too high, less danger to drop blood sugar low.
      As we  see in article, there is no insulin as treatment option. Metformin, with all side effects of it. What good metformin can do? Nothing. It leads to CVD , deposit of it in blood vessels. That deposits diagnosed as cholesterol, and treatment with wrong medicine started. Statins such as Atrovastatin, simvastatin, provastatin, do nothing good, and level of cholesterol skyrocket. At the same time TG getting above the level of survival. My level of TG was above 1000. I stopped to take all statins, and now only Lipitor is in my medical box. Usually doctors try to push me to statins, generic version of Lipitor. "It is the same!" - doctors usually insist. It is not, and I do know it way too well.
      With lipitor my cholesterol level is good, TG is above normal, but it is reflection to  my heart condition.

"Metformin is now recommended in line with insulin as medical treatment of GDM in both Norwegian guidelines, the guidelines of the National Institute for Health and Care Excellence, and the American Society of Maternal-Fetal Medicine (SMFM), but not in the guidelines of the American Diabetes Association," Dr. Hanem and Dr. Vanky noted.

        It is very good combination, just add some poison into honey and high profit will follow. Before that children and pregnant women were treated with insulin. What are the evidence that lead to add metformin to insulin? Obesity? Well, simple look at  the modern human population show big difference  in size. We are taller then we used to be. Compare new born babies, how long they are? Take a look at the teens. They are very tall. Chinese youngest  no longer tiny and short. They are slim, and really very tall. Take a look at the Chinese on Flashing China Town in NYC. They are born in America. Other American young also tall. It is easy to see in Lincoln Center, how different new generation of patrons. Really, what ADA and all our medical care will suggest now? Would metformin make new generation shorter? At least if population must be the same as in 1850 then something must be done to keep shortness in check.

In the new study, the authors looked at body composition in 141 PregMet study offspring when they were 5 to 10 years old. Twelve (17%) of the metformin-exposed children were obese, compared to one (1%) of the non-exposed children.

      As I published many times, stop to kill and start to heal. Diabetes cannot be treated as behavior misconduct and wrong life style.  Diabetes is medical condition. Treated with insulin diabetics live almost normal life. With time less diabetic will be born, and less diabetics will die. Well being of all humanity is on the stake  when diabetes treated right or wrong.

They concluded, "Randomized controlled studies are necessary for clinical evidence and good patient care. We, doctors and other caregivers have to continue performing them, even if they are laborious, challenging and expensive."

     Of cause  more studies needed. Also a new studies all the time show the same result as old studies? They show what studiers were paid for. 

via Ravenvoron