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Tuesday, 15 November 2016

What is Insulin? How MD Educate Diabetics. November 15, 2016

Really, Insulin, what is it?
Insulin is a protein chain or peptide hormone. There are 51 amino acids in an insulin molecule. It has a molecular weight of 5808 Da.
Really? Why peptide is hormone and insulin is just protein? For diabetics type 2, most  of us elderly and low income families which means there is no graduate studies, this type of education just the same as to show to a dog the video how to do tricks. Funny, but not effective. Really, what MD said that any diabetic type 2 would understand? Not too much. BTW, for MD education it is better to know that the same as insulin to be protein peptide is also protein. Insulin in hormone which means it carry on information. Peptide? " A dipeptide is made up of two amino acids joined by one peptide bond. ..." This is what info one will get when we google 'peptide'. 
Hormones are special chemical messengers in the body that are created in the endocrine glands. These messengers control most major bodily functions, from simple basic needs like hunger to complex systems like reproduction, and even the emotions and mood. Understanding the major hormones and what they do will help patients take control of their health. 
This what come out when I google 'hormone'. So, what really MD try to educate public? That we are not able to get to use internet? We do. We really can do it better then MD. This is why I usually say, trust in yourself more then in doctors. we have different values and goals. I need my health and well being. They try to get money from my health complications. Right opposite goals. Then more complication I do have then better for MD to get what they want.
 What does insulin do?
Insulin has several broad actions including:
  • It causes the cells in the liver, muscle, and fat tissue to take up glucose from blood and convert it to glycogen that can be stored in the liver and muscles
  • Insulin also prevents the utilization of fat as an energy source. In absence of insulin or in conditions where insulin is low glucose is not taken up by body cells, and the body begins to use fat as an energy source
  • Insulin also controls other body systems and regulates the amino acid uptake by body cells
  • It has several other anabolic effects throughout the body as well
As with the definition of insulin, which is out of any understanding the subject, the same about insulin action in the human and animal bodies. Insulin do not prevent fat from being used as energy. Really where this understanding come from? How do we loose weight? If we loose weight, it is fat which go out on belly area. As it is easy to see, MD mixed all about and around. What does it man that fat takes take up glucose from blood and convert it into energy? I even cannot discuss this absurd. I would not post it here if it was someone like me without medical degree. But it is MD education for public. Good to show what  absurdness they can present. This is why do I post it right here.
     Insulin is hormone which convert glucose into energy, and it happens inside the cell, all cells. Every cell is alive organism, independent with own function and responsibility. To be alive and to do the job cell needs energy. This energy come from glucose, fuel for body system to function. This glucose comes from food we eat. Molecula of glucose is very big, and it cannot enter into cell. Insulin's job to open the door for glucose to enter into cell, sort of. I am not medical pro. It is just very simple understanding. Better to take a look at the professional publications. Still, it better then MD frong presentation what job insulin do.
          It is true that fat can be converted as source of energy in case when glucose cannot be used as a fuel, that's right. In case of high blood sugar level fat can be used as source of energy, this process called ketosis.  But is it not insulin which prevent utilization of fat, but it is because of there is no insulin  in body to be used. Body cannot function without energy. Our heart need energy to pump the blood, and our lungs cannot stop to push the air. Brain cannot use fat as energy source. This is why diabetic skip into coma. Brain function shot down. When insulin injected, regardless one is diabetic type 2, type 1, LADA or MODY, or any other type of it, glucose became avalable for cell to use as nutrition.
       The job insulin do in body is complicated, and I am not sure that even now it is known all the functions of insulin. Still, the most important job insulin is doing, it keep us alive. Without insulin, the same as without nutrition, human cannot live. With high level of sugar in blood available to be used, we die from starvation. Simple shot of insulin, very small of this tiny hormone dissolved in water, we return back to life.
Insulin is synthesized in significant quantities only in beta cells in the pancreas. It is secreted primarily in response to elevated blood concentrations of glucose. Insulin thus can regulate blood glucose and the body senses and responds to rise in blood glucose by secreting insulin.
Other stimuli like sight and taste of food, nerve stimulation and increased blood concentrations of other fuel molecules, including amino acids and fatty acids, also promote insulin secretion.
Sorry, what is this, all this publication by MD? I see it is third grade first assay. Insulin secreted by pancreas, but not all insulin come form pancreas. MD suppose to know it. There is gland in brain which secret insulin. This insulin used for brain function only. When gland do not work and insulin secretion is limited, it is another problem, lost memory, and so on. Really, then more i read this publication then less I do respect MD, most of them.
Since insulin controls the central metabolic processes, failure of insulin production leads to a condition called diabetes mellitus. There are two major types of diabetes – type 1 and type 2.
Type 1 diabetes occurs when there is no or very low production of insulin from the pancreatic beta cells. Patients with Type 1 diabetes mellitus depend on external insulin (most commonly injected subcutaneously) for their survival.
In type 2 diabetes mellitus the demands of insulin are not met by the amount produced by the pancreatic beta cells. This is termed insulin resistance or ''relative'' insulin deficiency. These patients may be treated with drugs to reduce their blood sugar or may eventually require externally supplied insulin if other medications fail to control blood glucose levels adequately.
 Is this possible to find what is difference between tyupe 2 and type 1 diabetes? Why in one case it is 'insulin dependency' and in another case it is 'insulin resistance'? I still not able to get it. For me it is the same, both types need insulin to survive, but in one case type 1 diabetics get insulin injections right after they diagnosed with diabetes, and in another case, diabetics type 2, get insulin right before they too close to the final breath, and many of us do not get this chance at all.
       Really, if diabetes today number 7 cause of Death, and it is diabetes, high blood sugar level. It is not clear how many diabetics die every year. Heart attacks and stroke, cancer and lung complications, Ketosis and low blood sugar, heart failure and kidney failure, lung failure and gangrene, you name it. The question is, why if insulin can treat effectively every type of diabetes and take under control any, does not matter how high it is, level of sugar, why blood sugar level is not VITAL? It is so simple in present time, just one glucose strip, and it will show if one diabetes free or diabetic. Then after that any tests can be run. There is no blood sugar work for Americans. Our medical care providers wait for what? 
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What is Insulin?

By Dr Ananya Mandal, MD
Insulin is a hormone that is important for metabolism and utilization of energy from the ingested nutrients - especially glucose.

Reviewed by , BA Hons (Cantab)


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