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Monday, 19 December 2016

ADA. Classification of Diabetes and Types of it.. December 19, 2016

What is Diabetes? How ADA define Diabetes, and what is difference between types of diabetes?
       There are two general types of diabetes widely presented by ADA. Third type is Gestational, type of diabetes usually diagnosed in the second or third trimester of pregnancy. Also it is very easy to suggest that if pregnant woman is diabetic she would be diagnosed with diabetes during pregnancy. Do not be so fast. For this reason at first woman must have blood sugar tested. If there is no test like that then there is no diagnose that woman is diabetic. If woman is not diabetic then there is no way she would be tested to elevated level of sugar. So, there is no diabetes diagnose. Diagnose of diabetes would be delay to the time when level of sugar would be so high that woman would be transferred to hospital. If she is lucky of cause.
       Type 1 diabetes due to B-cell distraction, usually leading to the absolute insulin deficiency. 
Great, how insulin deficiency tested? That's right, 'leading' is progressive meaning, so it takes time for the diabetes to be developed to get absolute B-cell distraction. When it is started? How it was detected? How it was stopped to progress?
      Just take a look a little bit ahead and let us see, how diabetes type 1 was detected, tested, and diagnosed? The criteria for diabetes diagnose is the level of sugar in blood. It is one of those numbers:
FPG > 126 mg/dl
2 hour after meal >200 mg/dl
A1c > 6.5% 
Now say me, if it is FPG > 126 mg/dl  but < 200 mg/dl if this is diabetes type 1? Does it mean that B-cells distracted and there is absolute insulin deficiency? What about 700 mg/dl, is this type 2 diabetes with insulin secretion in sufficient amount and there is no insulin deficiency so there is no need in insulin therapy? Medical care providers usually say so. I do not trust in them.
      As I do think, it is simple just logical to ask doctors, what they can say about my B-cells. Do I still have them? Do I have Insulin deficiency or not? Simple, very simple and very logical question, what amount of B-cells do I have? What is the level of Insulin Secretion do  I have?
       There is no one mention how to diagnose insulin deficiency, when it is absolute or not. If so, then how diagnose can be made that 95% of diabetic population do have insulin in sufficient secretion and there is no B-cell distraction, and only 5% of diabetics population is so lucky to get one?
      Type 2 diabetes due to a progressive insulin secretory defect on the background of Insulin resistance. 
Now there is another question to ask doctors and ADA who published so clear recommendations how to classify and diagnose diabetes. What are the difference between 'progressive insulin secretory defect' and 'B-cell destruction leading to the absolute insulin deficiency'?  If progression to insulin secretory deficit does not lead to absolute insulin deficit? If so then when and how it can be detected?   What is difference between type 2 and type 1 diabetes? Still, no clue.
       Let me be a little bit more clear. Just let us take a look back to diagnose. Does this criteria of diagnose clear show that type 1 diabetic has absolute insulin deficit? Not at all. Diabetes type 1 can be diagnosed with any level of sugar, and very often it is diagnosed when kid cannot wake up and go to school. Kid usually has level of sugar higher then 400 or 500 mg/dl. Still, in standard care there is only lowest level of sugar when diabetes can be diagnosed. So, how type of diabetes was diagnosed in any case? No one mention in Standard Care by ADA.
       I do not say it is the case that with 400 mg/dl no one of us would be diagnosed with diabetes. Ether one can get diagnose of diabetes with blood sugar over 400 mg/dl., what type of diabetes? Personally I was diagnosed with diabetes when fasting blood sugar was 370mg/dl. I am diabetic type 2. The diagnose type of diabetes never was changed, regardless what level of sugar in my blood, what dose of insulin I need to compensate insulin deficit, and  that my C Peptide level, not fasting, just 3.
I do not have link to this web. It is ADA website.  Take a look at that Standards. They publish it  every year with some variations.

Standards of Medical Care in Diabetes - 2016



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