"Better treatments for obesity would make a huge impact on public health," adds Ayala. (Julio Ayala, Ph.D., associate professor at SBP and senior author of the study, published in the journal Diabetes. ) "GLP-1RAs are a tool towards that end -- if we can understand how they lead to weight loss, we may be able to design drugs that act on just the right parts of the brain, or modify GLP-1RAs to be more effective."Why do not start to study how medicine work and what effect it provide on its victims? Why it is so much matter how medicine impact on weight, and there is no one attention how it cut life of victim? Really, Victoza, what is it?
http://ift.tt/2hBqGZm
"GLP-1RAs cause people to eat less, and their weight loss effects were thought to rely on the hypothalamus, a part of the brain that controls appetite,"Sorry, professor, even I do not have appetite and even I hate to eat, and even I do have very severe vomiting as a result of eating when my stomach is full and there is no room for more food, I still hungry. This is how diabetes type 2 looks from inside. I do have very strong Will Power. I can refuse to take any meal, just do not eat at all. It does not last for long, less then two hours. After that there is no need in any food, any meal. Remember diabetes hunger coma? Before we skip into coma we just lost energy, not possible to take any move. In my case it is headache, very severe. This is how stroke come on.
I do understand, it is easy to say, I just have to control my appetite, stop to eat, lose weight, and there is no diabetes type 2. Every one say forever one wish. I am survivor. I fight for my life, regardless of I am fatty, pretty, ugly, or intelligent. I am Survivor! So, I do not take Victoza. But there are other people who took it.
April 20, 2012 -- Public Citizen, the Washington, D.C.-based consumer advocacy group, is petitioning the FDA to immediately remove the type 2 diabetes drug Victoza (liraglutide) from the market. The petition claims that the injectable medication puts patients at risk of thyroid cancer, pancreatitis, serious allergic reactions, and kidney failure.FDA approved Victoza as treatmnt for diabetes type 2 in 2010. Two years later victims of this medicine petition the FDA to take medicine off market. Just two years after medicine started its Deadly march.
http://ift.tt/2gx4CKp
Now 6 years after medicine still on market, our smart Medical Studiers found another way to make money. They study, what they can do about medicine which diabetics refuse to take? They suggest, this medicine works differently. It works in brain, and .... . Forever. Probably it reduce weight, and lead to ultimate weight loss. I still do not need it. I am Survivor. Regardless of my body weight, level of obesity, or any other abuse our medical care loudly pretend it is our fault and we did it for ourselves, I am not going to take any suicidal medicine which will lead to ultimate weight loss.FDA NEWS RELEASE
For Immediate Release: Jan. 25, 2010
Media Inquiries: Elaine Gansz Bobo, (301) 796-7567, elaine.bobo@fda.hhs.gov
Consumer Inquiries: 888-INFO-FDA
FDA Approves New Treatment for Type 2 Diabetes
The U.S. Food and Drug Administration today approved Victoza (liraglutide), a once-daily injection to treat type 2 diabetes in some adults.
Victoza is intended to help lower blood sugar levels along with diet, exercise, and selected other diabetes medicines. It is not recommended as initial therapy in patients who have not achieved adequate diabetes control on diet and exercise alone.
Insulin is a hormone that helps prevent sugar (glucose) from building up in the blood. People with type 2 diabetes have difficulty making and using insulin. Victoza is in a class of medicines known as glucagon-like peptide-1 (GLP-1) receptor agonists that help the pancreas make more insulin after eating a meal.
GLP-1RAs include liraglutide (brand name Victoza), exenatide (Byetta), and albiglutide (Tanzeum). They mimic the hormone GLP-1, which is normally released from the intestine following a meal. GLP-1 acts on the pancreas to trigger release of insulin and lower blood sugar, on the stomach to slow digestion, and on the brain to reduce food consumption, among other effects.So much work to do for one injection! Why do not use very simple way, just inject insulin, Lantus Solo Star, and there is no weight gain, no hunger, no any fancy side effects, no increased appetite, no leg lost, no rush on body and wounds healing perfectly and fast. Diabetics widely compared with addicts and alcoholics. Now with so many Trash Medicine loaded our medical market they load it with brain destroying medicine, to assure public, diabetics type 2 are mentally disable, and we have to be held in mental hospital.
Thanks you so much. I better to stay with my trusted Lantus Solo Star, and live my life as I can, mentally healthy.
I still do not get, do they mentally disable after medical school, or they just criminals in white coat?
Victoza Black Box: http://ift.tt/2hBmWqA
WARNING: RISK OF THYROID C-CELL TUMORS
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- Liraglutide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures in both genders of rats and mice. It is unknown whether Victoza causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans, as the human relevance of liraglutide-induced rodent thyroid C-cell tumors has not been determined [see Warnings and Precautions (5.1) and Nonclinical Toxicology (13.1)].
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- Victoza is contraindicated in patients with a personal or family history of MTC and in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Counsel patients regarding the potential risk for MTC with the use of Victoza and inform them of symptoms of thyroid tumors (e.g. a mass in the neck, dysphagia, dyspnea, persistent hoarseness). Routine monitoring of serum calcitonin or using thyroid ultrasound is of uncertain value for early detection of MTC in patients treated with Victoza [see Contraindications (4) and Warnings and Precautions (5.1)].
via Ravenvoron
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