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Tuesday, 10 October 2017

Clinical Use of insulin. Lily Research 1973. post 1.October 9, 2017

        Clinical Use of Insulin is chapter 7 in book from page 87 to 107. This is full chapter and this is how insulin was used in American Clinics before 1973. Later, in 1980 WHO developed a new understanding in diabetes treatment and therapy. It would be another chapter. By not there are a few post devoted to insulin use before 1973.
        Clinical studies were based on the  low insulin requirement. It is complicated studies, and today we do use another types of insulin, so this is not relevant for public diabetes studies. What I did, I took my personal studies to find out the time of insulin injections, type of insulin therapy, the dose of insulin, and the number of shots I need to keep blood sugar withing ranger. I took one hour studies. This means, I took blood sugar readings every hour regardless did I eat or fasting. Well, I did not took these studies at time I was sleeping. The point was, when we have to all the time connect insulin dose and time with meal, feeding, it is all the time somehow abnormal. It is not our lives that we only eat and sleep or do work out. We still do have our lives to live. So, this study was to find out what to do to keep blood sugar under control in daily life.
        In my study I found that lowest level of sugar is not fasting but at the end of the day, around 4pm - 5 pm. Why this is so? well, I am not going to answer to all Why? I simple post what I do, and there is no advises or instructions to any one. Also it was important that to keep blood sugar smooth and nice I have to take 4 shots daily, to avoid swings from high to low. All dose of insulin divided on  four shots. In the morning the dose was higher, lowest dose in the eve before bed. If insulin injections is too high at bedtime I could not fall asleep, still waken. So, I took shots not even but according to my life style. I have to be wake up all day, and be able to get nice sleep at night time.     
        Another very important discovery was that I cannot take short acting or rapid acting types of insulin. Does not matter how hard I tried I was not able to control sugar. I all the time was on high-low swings. So, I simple gave up Novolog, and after that never returned to this type of insulin, with any name of it. So, I stopped on one type, long acting insulin Lantus Solo Star, insulin in pen. Later I tried another type of insulin, Toujeo. It did not work for me and I do not take it now.
      This is all about timing and typing of insulin. If one is interesting one can buy the book and simple read it. I do not copy books. I read them and study them, and then I share my studies with readers.
In the treatment of diabetic patients undergoing stress, such as surgery, severe illness,or injury, insulin can be added to intravenous fluids. (Page 89.)
 This part of clinical use of insulin I would like to reject completely. To add insulin other then in injection is very very questionable. If it is my choice I would not allow it to do for me. Insulin is very complicated medicine. That one moment, very widely spread, that with life style modifications, starvation diet, diabetes type 2 can be reversed. Does patients who undergo surgery on other then starvation diet? Patients do not allowed to eat. At the same time a lot of medicine added to blood stream. Now the question is, how many units of insulin must be added in IV to fluids? Lily research studies did not answer to this question. Just add insulin, but how much? What if there is low sugar, how to deal with it if patient after surgery and cannot eat? 
       There are many questions can be asked, still, there is no one who will answer to any one of them.
      Personally, I do not like to have any insulin added to IV. I prefer to keep my blood sugar under my control. What I would like to suggest, before any surgery diabetic must be on stable dose of insulin and well tolerate it. That-s right, very often surgery is emergency, so there is no way to get ready to it. But with attention to the general public health many surgeries can be avoided with proper diabetes treatment. Just let blood sugar be Vital. And if any abnormally elevated level of sugar in blood, let treat it with insulin, the same as antibiotics. Probably there would not be surgeries, and no need to add insulin in IV fluids.


via Ravenvoron

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