How many types of medicine diabetic type 2 need to control blood sugar numbers?
It is depend on the Shaman Dancing around Fair. Every bit of dumb is add-on medicine for diabetic type 2. Try to survive, if you can.
If you give your patients complex regimens that have to be taken in the morning and then again in the evening, patients tend to forget doses. Therefore, adherence may be compromised, leading to diminished diabetes control.
How diabetic can forget the dose of medication? It is all the time on the bottle with medicine. Simple, take a look at the Rx, and take the dose one need to take, regardless it is morning or evening.
With our very busy lifestyle we easy forget to take medicine then forget dose of it, and it is also regardless it is morning or eve, and if it is once or twice a day.
Next, what does it mean when patient forget to take medicine? Who will remind to patient that medicine must be taken? If patient self-concerned then there is no one will remain better then own condition. If I forget to take BP medicine then my BP is strike, and I do have severe headache. To avoid to take additional Excedrin, I try really very hard never forget to take medicine.
If I forget to take Insulin then soon I will hive high sugar, hunger, be weak, and ... take Insulin right away. Because of most of us live with families, our families also remember, we have to take our medicine, and they remain it to us.
On a background of metformin, if the patient has failed other combinations, such as with a sulfonylurea or a DPP-4 inhibitor, people have added basal insulin. If your patient is failing with basal insulin and you need to take another step, remember that the largest meal is often in the evening.
As many times it was presented that diabetes type 2 caused by obesity, high calorie intake, and it is well established, how? Simple question, and there is no any answer to this question: how was established that diabetes type 2 caused by high calorie diet? Let us start with the fact that type of diabetes has no marks to be diagnosed. It is also very well established and widelly presented by Medical Publications. If there is no mark to diagnose type of diabetes then say me, how cause of what is not known what, was established? Simple absurd.
Still, this absurd is widely presented by every one Med Pro, and every one of then educate diabetics what to do.
There is another absurd in this publication. There are combination of Metfromin and SU, and this combination fail to treat diabetes, to control high blood sugar numbers, so ...MD suggest to add-on basal insulin. Sorry, if SU combined with Insulin then it is really very high ride on high-low swings. No one blood sugar control possible. DID author of article tried this combination of drug cocktail by himself? I suggest to try it. I will not.
You could combine the basal insulin with a GLP-1 agonist, such as a combination of insulin degludec plus liraglutide. Patients could take that just once with their largest meal, which would be in the evening, and it would be very effective in controlling their blood sugars.
So, it is already fourth medicine to take, and all time remember, there are side effects, and of cause interactions. Why so many medicine needed to control blood sugar? Because of author has no one idea what he is talking about. It is said in the beginning about dose of medicine, but at the end of own publication author simple forgot that any medicine must be taken in certain dose. There are four different types of medicine sugessted, and no one medicine given in what dose it must be taken. At least, before add -on any additional number of medicine it is better to try to increase dose of medicine. At least, probably with higher dose there will no need to take add-on?
Why medicine does not do the job?
It is wrong type of medicine.
it is wrong dose of medicine.
It is wrong regime of medicine.
In medicine is right, dose is right and regime is right, medicine will do the job.
Well, it is easy to say, I am wrong. There are many patients take different medicine to control, to maintain, or to cure disease. Tha's right. But in case of diabetes every one add-on simple do not do the job. Numbers still high, regardless of number add-ons. So, there is something wrong with add-ons.
Now, let us take a look at the suggested medicine.
Metformin.
This medicine never decreased level of sugar in blood. Yes, many diabetics type 2 suggest they 'reversed' diabetes type 2 with Metformin.This is the nature of diabetes. Numbers all the time go up and down, regardless if it is with metformin or better without it.
GLP-1.
GLP-1 has multiple physiological effects that make it an attractive candidate for type 2 diabetes therapy. It increases insulin secretion while inhibiting glucagon release, but only when glucose levels are elevated , thus offering the potential to lower plasma glucose while reducing the likelihood of hypoglycemia. Furthermore, gastric emptying is delayed and food intake is decreased after GLP-1 administration.
At first, it is closer to SU. This medicine increases insulin secretion by diabetic's type 2 ill pancreas. Needless to say, with time insulin secretion will decline. Diabetes type 2 progress to the fatally high level.
Second, in time between meals our body system uses glucagon which released by liver. GLP-1 effect liver, and this is why every diabetic type 2 has non-alcoholic fatty liver disease.
Lastly, if there is no low blood sugar then medicine does not effect diabetes cause, and so it is nether ether treatment, nether cure of diabetes. Because of Insulin is very well established most effective treatment and even cure for diabetes type 1, it is obvious that low sugar is not avoidable when medicine is effective to treat diabetes type 2.
SU,
Sorry, SU never worked good for diabetics type 2. It is ether safe, nether effective medicine for diabetics type 2. It has side effect to lead to uncontrolled and very unpredictable low sugar. It is also destroy insulin secreting Beta Cells, so with time there is no insulin secretion by diabetic's type 2 own pancreas. This is why diabetics type 2 die less then within 10 years after being diagnosed with diabetes type 2.
Basal insulin.
Why basal insulin does not control blood sugar level?
Simple, add - on dose, amount of units, and insulin will do the job.
Basal insulin does not depend on the meal diabetic take, or time of the day. Just take this shot in the regular time. What is very effective, the dose of basal insulin. It is the same as if we take one bread, and we were told that we were fed, then do not be surprise that we are hungry. This is elementary, and every one do know it. If so, then say me, why it is only type of medicine in discussion, no numbers of level of sugar, or dose of medicine? How this discussion can be reliable?
Still, people, Med. Pro,. put their voices, and discuss how to treat what they do not know what they treat.
Does not all this looks familiar? Yes, it is 1000's years, and the same therapy. It was all the time named Shamanism.
Put the Focus on Dinner for Blood Sugar Control by Cyrus V. Desouza, MBBS
https://www.medscape.com/viewarticle/904180?nlid=126056_1521&src=WNL_mdplsfeat_181113_mscpedit_wir&uac=164666HZ&spon=17&impID=1799763&faf=1