Source: National Institute of Diabetes and Digestive and Kidney Diseases -
via Diabetes
So simple. If today we do not eat, would we die? Not at all. We use the meal which was stored in body after many other well sunny days when food was available for us. Very often it is presented that if Diabetic type 1 skip one dose of Insulin diabetic type 1 can die. True? Not at all. Diabetic type 1 will not die after skipped dose of insulin, does not matter how high this dose of insulin is. I mean, it is ordinary day, not the time in ICU. The same with everything. We will not get in deep problem if we do not have money for one day. we can survive day without food and water. And so so on.
- Date: May 20, 2018
- Source: European Society of Endocrinology
- Summary:
- Fasting every other day to lose weight impairs the action of sugar-regulating hormone, insulin, which may increase diabetes risk. These findings suggest that fasting-based diets may be associated with long-term health risks and careful consideration should be made before starting such weight loss programs.
Generally, to correct a high blood sugar, one unit of insulin is needed to drop the blood glucose by 50 mg/dl. This drop in blood sugar can range from 15-100 mg/dl or more, depending on individual insulin sensitivities, and other circumstances.well, today my blood sugar, fasting, 135 mg/dl. I need 100 mg/dl. So 35mg/dl I have to correct, right?
Generally, one unit of rapid-acting insulin will dispose of 12-15 grams of carbohydrate. This range can vary from 4-30 grams or more of carbohydrate depending on an individual’s sensitivity to insulin. Insulin sensitivity can vary according to the time of day, from person to person, and is affected by physical activity and stress.The difference between 4 and 30 is big. So, it is better to start with sensitivity to insulin, and how to find it.
The general calculation for the body’s daily insulin requirement is:
Total Daily Insulin Requirement(in units of insulin)
= Weight in Pounds ÷ 4
If your body is very resistant to insulin, you may require a higher dose. If your body is sensitive to insulin, you may require a lower insulin dose.
Please keep in mind, the estimated insulin regimen is an initial “best guess” and the dose may need to be modified to keep your blood sugar on target.
Also, there are many variations of insulin therapy. You will need to work out your specific insulin requirements and dose regimen with your medical provider and diabetes team.
Addressing Generic-Drug Market Failures — The Case for Establishing a Nonprofit ManufacturerPrice for medicine is not only genetic. This medicine usually very not-expensive. What about Brand Medicine? It is all up to manufacturers, regardless how many of them and if they do have competitors or not. This is why every Big Pharma manufacture try to develop medicine as fast as they do, and get FDA approval in front of competitors. Now take a trip back in time when Insulin was developed and first diabetics were treated with Insulin. There was only one company which manufactured Insulin, still within one year, just one year, price to Insulin dropped by 95%. They did not have competitors. Why price was dropped in first place?
by Dan Liljenquist, J.D.,Ge Bai, Ph.D., C.P.A.,and Gerard F. Anderson, Ph.D.
https://www.nejm.org/doi/full/10.1056/NEJMp1800861?query=TOC
In 2010, for example, Valeant acquired the rights to Syprine (trientine hydrochloride), a drug invented in the 1960s to treat Wilson’s disease, a rare condition, and subsequently raised its price by more than 3000% for a monthly supply, from $652 to $21,267. Similarly, in 2015 Turing acquired the rights to Daraprim (pyrimethamine), a drug used to treat toxoplasmosis, which has a market of only 6000 patients in the United States, so that one manufacturer could supply the entire market. Turing then raised the price of Daraprim by more than 5000% for one tablet, from $13.50 to $750. In these and other cases, policymakers and economists have asked, “Why don’t other manufacturers enter this seemingly lucrative market?”Would competition solve the problem? Really? In this example rare condition, and I am sure it is not these drugs so skyrocket the profit of manufactures companies and Big Pharma. Let us take a look at the common drug, Insulin. There are many competition. Different companies, different types of Insulin developed and still under developing. Why price is so high? One box 5 pens of Insulin cost about $400. It is medicine which if diabetic left without it, will lead to severe complications, and Death. So, diabetic will pay for this medicine, in expense of any other medicine diabetic needs. And we need a lot more.
NVOKANA® can cause important side effects, including:This is Invocana. Diabetes type 2 preventable. How? Eat right. Work out regularly. Take your medicine. Now say me, how to prevent amputation if Invocana, medicine to reduce level of sugar in blood, leads to amputation? No prevention to this side effect of this medicine. Now there is the question, why take this medicine if this medicine leads to so severe side effect? Really, why take this medicine?
- Amputations. INVOKANA® may increase your risk of lower-limb amputations. Amputations mainly involve removal of the toe or part of the foot; however, amputations involving the leg, below and above the knee, have also occurred. Some people had more than one amputation, some on both sides of the body. You may be at a higher risk of lower-limb amputation if you: have a history of amputation, have heart disease or are at risk for heart disease, have had blocked or narrowed blood vessels (usually in leg), have damage to the nerves (neuropathy) in the leg, or have had diabetic foot ulcers or sores. Call your doctor right away if you have new pain or tenderness, any sores, ulcers, or infections in your leg or foot. Your doctor may decide to stop
your INVOKANA®. Talk to your doctor about proper foot care
- Dehydration. INVOKANA® can cause some people to become dehydrated (the loss of too much body water), which may cause you to feel dizzy, faint, lightheaded, or weak, especially when you stand up (orthostatic hypotension). You may be at higher risk of dehydration if you have low blood pressure, take medicines to lower your blood pressure (including diuretics [water pills]), are on a low sodium (salt) diet, have kidney problems, or are 65 years of age or older
- Vaginal yeast infection. Women who take INVOKANA® may get vaginal yeast infections. Symptoms include: vaginal odor, white or yellowish vaginal discharge (discharge may be lumpy or look like cottage cheese), or vaginal itching
- Yeast infection of the penis (balanitis or balanoposthitis). Men who take INVOKANA® may get a yeast infection of the skin around the penis. Symptoms include: redness, itching, or swelling of the penis; rash of the penis; foul-smelling discharge from the penis; or pain in the skin around penis
Deaths: Diabetes remains the 7th leading cause of death in the United States in 2015, with 79,535 death certificates listing it as the underlying cause of death, and a total of 252,806 death certificates listing diabetes as an underlying or contributing cause of death.Why today Diabetes is number 7th leading cause of Death in the US? Really why? With diabetes type 2 which counted 95% of diabetics population, it is type 2 diabetes which caused death, not type 1 diabetes. It is diabetics type 2 who lost limbs before death. And it is diabetics type 2 who developed all the complications diabetics accounted. Why it is type 2 diabetics who carry on so severe and devastated danger of medical condition which can be successfully treated today?
http://www.diabetes.org/diabetes-basics/statistics/?loc=db-slabnav
Type 1 diabetes is usually diagnosed in children and young adults, and was previously known as juvenile diabetes. Only 5% of people with diabetes have this form of the disease.Diabetics can be at any ages. Diabetes can be diagnosed at any age. What makes it so special that diabetes diagnosed in children and adult different in type? Nothing. But age play important role in society. The same as money. It is just said that children diagnosed with type 1 diabetes. But if take it more deeper then we will see that Noble society does not have diabetes type 2. And most important. diabetes type has no diagnostic tools. All types of diabetes diagnosed with the same, abnormally elevated level of sugar in blood. So, what is the reason for all those types, regardless it is type 1, type 2, 3,4,5, and many to come? Nothing. Diabetes is the insulin secretion which is not sufficient. It can be due to severe illness, or many other couse. Still, the treatment is the same. If there is elevated level of sugar in blood then there must be Insulin added in injections. No any way around found so far.
Insulin total breakdown for 24 hours on 4/24 |
Bolus history 4/25 |
4/24 bg from early in the morning. Elevated morning bgs thanks to a low bg in the middle of the night. |