To Fogive, to Forget, and Dream. September 29, 2017

'To forgive' does not mean 'to forget'. It is easy to say, but very difficult  to get really 'to forgive' what is it? I cannot forget what was done for me, it is too much pain, and this pain was hidden inside many many years. It is all the time with me, never leave me alone. Do I want to remember it? Not at all. I wish I can forget, and I cannot forget it. I wish I forgive, but I have no one idea what is it and how to do so. If forgiveness will free me from my painful memory, I am happy to forgive. But my memory stay with me, regardless if I forgave or not. So, really, to forgive, what is this about?
     If N one who did bad things for me and now I have to forgive N then it is depend what this N doing now. If N still around me, then there are a few possibilities:
N will stop to hurt me;
I will move away from N to be sure N never would be able to hurt me anymore;
All stay as it is and I accept that N hurt me. I try to forgive to survive.
There are another possibility. N is not around. Actually N already gone and there is no way N can hurt me anymore. What is in this case? If I  forgive N  or not has no any meaning for N. It still hurt me. Probably even more now when N is gone and N never will pay for what he (she) done for me. This hurt and stay with me. My inability to forgive and move on hurt me, hold me back.
      There are our Dreams come to help. In my dream I see N, and N still hurt me. But different then in reality, I fight, I resist, and I hurt N back. The act I never had done in reality, I do in Dream. It still hurt. It still pain, emotional pain. But when night passed, the dream staid in past, and step by step I can move on from painful past.
      It is right. There is no need to forget. It is wrong that we have 'to forgive'. It is all the time told, we need to forgive someone because of it is good for us. The problem is, I do not see I get better. I still hold this pain, and it still hurt. When in dream I fight it is like I fight in real word, in past when I just took life as it was, and let N hurt me. Never fight back. Now I do, I fight. Does not matter if N is already gone. I think we do not leave this word as we never had been here. Actually I do believe we have Soul and this Soul take over all our Sins and wrong doing. The same as it take all right things we do. But in case of N it does not matter. I do not think about N. I simple try to move on.
      Why do I need to fight N if it is already past? Why do I need to fight N in  my dreams?  Because of in this case I changing. My inner Soul is changing. And there is no way that another n will be able to hurt me. This is why I have to fight. To see that fight is my protection, my survival. It is I who done wrong with N. It is I who let N hurt me. I have to be able to fight, to find my way to protect myself. This is why I have to do so.
      Dream help me to understand N was bad person. No need to pretend, it was all right. Not at all. N does not deserve to be forgiven. I need to move on,  and it does not mean I have to forgive N. It is not my duty. It is not my responsibility. We all responsible for our own actions. I am responsible for mine. I have to move on. Not to forgive or forget but to learn from my mistakes or weakness, and recovery to be stronger, emotionally stable. In this case N not able to hurt me anymore. N stop to exist for me. I do remember all, but it is all 'Past', it is all "it was" and not I do have life and future without pain caused by N.

via Ravenvoron

Diabetes type 2 Myths and Tricks. September 29, 2017

        Diabetes type 2 first line treatment is Life style modification, diet and exercise and if it is not enough then metformin added. Does it work? Of cause not. Every med pro do know it very well. Then why it is first line in treatment of medical condition such as diabetes? Because of without first line there  is not second line. So, after first visit to clinic two weeks later there is another medicine would be added, SU. Now for a few years doctor charge health plan for every month victim visit to the clinic. There are ECG and blood works, different types of therapy, which is usually in the same clinic under supervision of the same doctor, or closer MD friend. It is almost ten years in front to treat diabetic in this way till diabetes take full power. Then there are a few years of incentive therapy with amputations, pacemakers, home aids, nurse visits, and so on. They are 'add-on' to medical money pool. And finally, it is hospital, death, and organ and tissue to transplant. Final harvest.
       Every one count how much diabetes care cost to society. No one count how much diabetics type 2 pay for own life. Where all those money go? In private pocket of Con MD. Is this really possible to get rid of diabetes type 2 with any treatment, first line or any add-ons, newly medicine or old one? I do not think so. This is why year after year there are more and more diabetics type 2. Today it is even not epidemic but pandemic. Say me, why Zika virus did not became pandemic? Why many other epidemic stopped before these epidemic claim millions of lives? Because of they are not so profitable. Or they can take lives regardless of income of victim. Diabetics type 2 are low income low level of American Society. This is why they must control Diabetes type 2 with life style modifications. High society does not need this sufferings. They take Insulin, and live with small inconvenience of daily insulin injections.

I don't necessarily agree with  your statement about pharmaceutical firms but I will say this.  I practice in a large metropolitan outpatient hospital clinic.  I regularly have patients who cant afford the basal insulin products prescribed because of copays and insurance restrictions.  Many times these patients can be switch to NPH insulin (Novolin or Humulin) and there copays and price to the insurance carriers are greatly reduced.  It has the same glucose lowering properties except its given twice daily.  Why are many physicians not making this change?    

Now so true. Usually insurance company ask if there is some reason that more expensive medicine must be taken.  It is not that they do not pay for this medicine, they just make sure, this medicine and spending necessary. There is no need to switch from one medicine to another. Also it is practice that before patient get different medicine pharmacy contact doctor if switch is acceptable. If doctor insist, there are no another medicine but this one, then insurance will pay.
       Co-pays payment that patient cannot afford is really another myth. If one work then family can afford to pay co-pays. If there is low income family then there is no any co-pays, high or low. Simple, diabetic cannot afford visit to medical clinic and pay to MD. So, it is really trick that insurance companies does not pay, and co-pays so high, diabetics cannot afford to pay it. If there is no co-pays as it is with Medicaid for low income families, then MD give Rx to medicine to any patient who really does not need it. Check up for this practice.
      Insulin such as NPH, Novolin or Humalin is really in very reduced price. The problem is, it does not work very well. It is regular type of insulin. The basal insulin such as Lantus Solo Star, in pen, or Lantus actually can be the same price because of it is high quality and effect of this type of insulin. With time or when this insulin started to be taken early it is the same price, and even lower. With time dose of Lantus Solo Star dropping, so the price of therapy go down.
      It is Myth that properties of insulin are the same and it is only the price what is matter. Insulin has different properties, and it is not exchangeable. Some insulin work perfectly well. Other types work less effectively, and some does not work in positive way.

Also, please explain to me why we have such obese patients who are diabetic and we do not rigorously pursue the treatments that work, weight loss and exercise and diet.  It seems to me we are treating after the fact since its easy and does not require much effort.  Throw meds at them.  I know there are some patients the easy may not work, but there are many who would benefit.

I tried to answer to this question in all above. If question still not answered then please continue reading. There is one one way to find out obesity, bathroom scale. Still, bathroom scale does not show the difference between fat and edema, water retention. Severe edema lead to the condition when water go through the skin, skin get infected, amputations which really does not solve the problem. The idea of weight loss really has no any meaning. For what degree weight can be lost? I really do not want to discuss this absurd such as weight loss. This 'therapy' work for no one. This is why it is 'first line' which mean, there are second line will follow, and then add-ons one after another.

New paper shows how to treat type 2 diabetes. All based on just discovered new pathway of glucose metabolism. http://ift.tt/2kciL6X   

There is another trick. Diabetes is not metabolism. It is endocrine system disorder.  There are now type 2 diabetes. There are chronicle poorly treated or never treated medical condition, usually infection which lead to the pancreas disability. Disable pancreas cannot work correctly and cannot support healthy living. This is with time diabetes progress and finally it is fatal. Insulin in injections can not only safe diabetics lives but also cure diabetes in incoming generations, decrease epidemic and prolong life span.

SULPHONYL UREAS ARE NOT COMPLETELY BAD ACTORS THEY ARE GENERIC AND REDUCE HBA1C IT IS TRUE OF HYPOGLYCEMIA BUT PT IS AWARE OF IT AND THEY ARE CHEAP AND IMPROVE HBA1C.

It is not my style to type in this way. I just copied the comment. Now, SU is cheap, this is true. And it is all what is True in this statement. SU lead to very low blood sugar, absolutely not controllable. Also it lead to the pancreas disability, to kill insulin producing beta-cells.  Of cause if high sugar 400 mg/dl combined with low sugar 40 mg/dl. the A1c is almost perfect, 220 mg/dl. Still, to flog disable horse never lead to get closer to destination.

THE POST MARKETING TRIALS ARE SCARY AS THEY SHOULD HAVE BEEN DONE FIRST BEFORE RELEASE.

Really, why people so love to yelling? Just think about, what this MD doing in his clinic where patient is 100% helpless. Now about those trails. Really, why MD does not run his trails? He must. He is responsible if medicine he Rx work for this patient or not. But no one of them do control Rx they provide to victims. This is why today at first it is Rx, and then it is De-Rx. So funny! They really does not understand how ridiculous they are in all comments and articles they publish.

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Sunshine Act and Effect of Big Pharma on Diabetes Treatment. September 28, 2017

I can give you my clinical opinion, which is that, yes, increased use of the newer insulins is a good thing. Administration is via a pen, which is easier to use; they only need to be administered once a day; and hypoglycemia is less of a concern.
Matthew Mintz, MD, an internist and clinical associate professor, also at the George Washington University School of Medicine. Dr Mintz writes frequently about the drug industry and trends in prescribing.
 http://ift.tt/2xAWUva

Sorry, my patient opinion is that MD has no one idea what he is talking about. He has no one idea what is insulin, old or new, what is diabetes in past and in present, and nothing about cost and effect of medicine. Prove? Read it in the hes own writings.
      Yes, to use pen is easy. I can use my insulin pen in any place, in my car, even in Met Opera house. Very convenient.This is why I prefer to use Lantus Solo Star rather then Lantus. But the statement, insulin in pen need to be administered only once daily is perfect medical barbarism. Insulin used in dose, in units, and dose depend on the the stage of medical condition. To say that way of administration has high effect on the medical condition show up that MD is Con Man, one who write and has no one understanding about subject. Personally I take up to 4 shots daily. I take insulin in pen, Lantus Solo Star. I need to inject 300 units daily dose. It is not possible for me to take this dose in one shot.
      Hypoglycemia in condition when insulin dose is too high, or there is nothing to digest due to very low diet. This condition not effected by the way of insulin administration, but be the dose of insulin, timing, activity of diabetic, and many other inner conditions. This is why one can feel low sugar with 100 mg/dl in blood, and another time it is 60 mg/dl in blood but diabetic is not in condition of low sugar.
      Back to MD. He better to know that short acting or rapid acting insulin lead to low sugar regardless if it is administered in pen or in any other ways. Even more then that, SU which are administered orally, it is tablets, not injections, lead to the same low sugar as it is insulin, but more difficult to be controlled.
     Really very interesting, what they teach in Medical Schools?

Now, the downside is that these newer insulins cost more money. So, is the increased spending on better insulins worth it?   

As usual, what really is important, the cost of medicine or diabetic's life? It was time when insulin was not available, so the treatment of diabetes was based on Art of Medicine, Starvation, drops of Opi or  Arsenic, and organic milk. 100 years ago the talks about organic food was the same effective as it is today. Why in all discussions about diabetes treatment it is cost of medicine put on the front line? No one count the cost of treatment cancer or addiction, flu or dental costs. Every one count the cost of treatment for diabetics. What are those costs? Amputations. Home care. Medical equipment such as scooters, treatment for Asthma and Sleep Aphenea, disability, weight loss surgeries, funerals, and so so on. This costs are not in account  when doctor make his mind what to Rx to victim, insulin in pen, very expensive, or Metformin and Invocana, less expensive medicine which lead to amputation, disability, and funeral costs. Really, is newer insulin really better and worth to spend more money then Invocana? It depend, who get what.

 There are some exceptions when treating diabetes. Metformin is a great drug that is very safe and very effective, and every guideline suggests that it be used first line.      

Sorry, what is this really about? That's right, first line is what? The first line is that victim come to this particular clinic first time. So, if one with diagnosed diabetes over 10 years come to clinic, the first line would be Metformin. Metformin did not work to prevent diabetes in first place. It did not work 10 years to bring blood sugar under control, and this is why diabetic come to a new office, in attempt to find what can be helpful to treat high numbers. But victim is first time in clinic, so the first line of treatment is .... .
      I suggest another way. Every one diabetic take Metformin. Now look at, how Metformin improved blood sugar control? It did not in no one way. As MD said, more and more drugs are needed. In contrary with Metformin I take less and less dose of insulin injections. Highest dose in this year was 434 units. Now it is less then 300 units daily dose. No any other types of medicine to address to treat high blood sugar numbers, just Lantus Solo Star. It is insulin pen. Now I can tale all 300 units in just two shots, 160 in the morning, and the rest of the pen in the eve.There are 307 units in each pen.

However, metformin does not work 100% of the time in all patients with diabetes. In fact, most of these patients will need more than one drug.

Simple, most effective, medicine does not work at all. But what I suggest to ask those of us who used to take Metformin year after year, till blood started clotting and stroke of heart attack stopped our hearts. what side effect we do have after using so effective medicine? Pain in muscles. Pain is so severe that there is no spot in our bodies without pain.  This side effect never was published. We all do have it. It takes time to get rid of Metformin from body system and be able to ease muscles pain.

So let's talk about that drug. Invokana, which is also marketed as a combination drug with metformin (Invokamet®), reduces glycated hemoglobin very effectively. It causes patients to lose weight, which is often helpful for patients with diabetes. It also lowers blood pressure, and many patients with type 2 diabetes have high blood pressure. And more recently it has been shown to have cardiovascular benefit. Metformin, despite numerous studies, has never really been shown to decrease heart attacks or strokes.

Almost myrcle drug. Read comments to this publication. 

Recent reports of canvas and canvas R and FDA bblack box warnings on incresed incidence of Amputations in patients taking Invoana debunks the so called benefits.

Well, Invocana is highly effective diuretic. Water retention is one of the symptoms of diabetes type 2.
water does not go away in the healthy way. It is stay between cells. Diabetics type 2 gain weight. This is why diuretics are the really first line in all treatments, diabetes, high blood pressure, heart stroke, and so so on. Regardless of how effective diuretic is, water does not go away. It starts to melt skin, flesh. Infection. Amputation. But amputation of legs does not effect the water retention. The problem was not solved.
 Other parts of body get effected. More amputations are needed.What doctors Rx for this condition? That's right , work out. They Rx physio Therapy, but ..... . The picture taken in Summer. Not it is September last days. The legs and hand much better. The arm is not. It started to effect arm, from hand to elbow. I do take insulin since 2011. If I did not dropped all SU and Mdetformin and all other types of Junk Medicine I would not post today. But I am do. Even more then that. I still use two my legs. I still use two my hands.
Now there is the question, the amputations and disabilities which were resulted by treatment with first line medicine, did the cost of this condition added to the cost of Metformin and SU? I do not think so. The cost our society count is, metformin is $4 month supply, and one box of Lantus Solo Star is about $400. I need 6 boxes a month. $2400 monthly insulin supply. Really very expensive. No one of us, diabetics type 2 can afford to buy insulin. Insulin Resistant type of diabetes, Insulin Independent type 2, it the type of diabetes when dose of insulin to control blood sugar is higher then 200 units daily.
The article published by e-journal

If you want to save money, you can use the cheaper drugs, but cheaper drugs don't necessarily work as well and have more side effects. So what do you want to do? If you're the doctor, you want to do the best thing for your patient. If you're a patient, you want to get the best medication.

So pathetic conclusion! I suggest to say it in better words. If you are healthy but need to show to somewhere you are diabetic, use cheaper drugs. They do have the same effect on society but cost less and usually free with health plan. No co-pay. 
If you are doctor then think about what cost it to you to Rx effective medicine or get higher check from Big Pharma. So, Rx a new drug, and get payment, but do not Rx medicine which will heal patient and you will lost health plan payment.
If you are diabetic, patient, then think twice or even more before trust in any doctor. Be smart. Get educated. And do not take it for granted that MD or any title really provide good health care options. Run your log book, for yourself and for your family. And keep you medical box under your control, regardless it is cheap or expensive.

via Ravenvoron

Universal Death Prevention or CMMP. (Con Men Med Pro). September 28, 2017

WEDNESDAY, Sept. 27, 2017 (HealthDay News) -- Falls and fractures are a major cause of disability in old age. An influential U.S. medical task force is recommending exercise and, in some cases, medical evaluation to help seniors stay on their feet.

       8 millions of diabetics type 2 in America. How to prevent diabetes type 2? Diet and work out. The result of prevention is that Diabetes type 2 is number 7 cause of Death in America. In NYC it is number 4. Well, it is easy to say, there are two types of diabetes. actually, there are more then two. But 95% of all diabetics population are diabetics type 2. So, do your math, who stand on number 7 spot to grave?  Diabetics type 2 done less then withing 10 years after being diagnosed with diabetes type 2 and started to be treated with starvation dieting and intensive work outs. In contrary diabetics type 1 treated with insulin and live next 60 or 70 years with small inconvenience to take insulin shots.
       Now, let us see, how to prevent falls? Exercise. Really? Why people use to fall in first place? Is that really true that only old aged population fall? Not at all. My first black out was when I was a student, age 18.  It is not that I was drunk, I never was. But I am diabetic type 2. As every one diabetic type 2 I do have low vit D. Say me, why? I do live on 4th floor with windows opened to the South. I spend all Summer outdoor, on Adirondack lakes, open to sunshine. Vit D even not vitamin. Our body system can make it from sunshine. So, why my vit D is all the time low? No one supplement can fill the gap. If sugar in blood is high, then Vit. D level is low.
        I go to Lincoln Center, NY Phill. There are many old aged people. It is nothing  extraordinary to see that old folks fall on the floor. Actually, it is happen every eve when I am there. Old people difficult to keep balance. When we start to fell we cannot control our bodies as we used in past. We simple fall. But really it is not that falls which bring old folks to hospital bed. This old aged folks fall and get back to the feet. I saw no one when paramedics were called.
     It is different when we fall because of we lost conscious. There is no way to keep balance. We just fall as we are, usually face down. This what bring us to hospital. we fall and we cannot get up to the feet. Also, it is not so clear, we die before we fall or after. That's right. It is possible that people not simple lost balance, but lost conscious and at the time we landed face down on the floor or the path we are walking, we already dead.
     So, back to Con Men Med Pro. What they suggest? Exercise to prevent falls. But as we just found it is not simple fall, it can be lost conscious and Death when we fall. So, it is easy to assume, exercise would prevent falls as result of lost conscious and Death, and it is universal treatment. It is even more convenient, if one still fall and die then it is because of one did not exercise, did not follow doctor's order. There is nothing what Con Men can do. We do not follow what they recommend.

via Ravenvoron

The Drop-Off Line

For a couple of years now my daughter's had a little inventory she's run through before leaving the house for almost anywhere, except, for some reason, school:

"Phone. Meter. Dexi." If one of them isn't on her person or in her bag, she'll go get it. If she's got it all, she heads out the door.

On day seven of school I received a text: I forgot Dexi. The Dexcom receiver was, indeed, still sitting in the kitchen.

Day 10 brought a similar text, except she'd also forgotten the meter:

The school is only a couple of blocks away- a two minute drive at the most. Unless it's 15 minutes before school starts. Then it's an excruciating crawl with both vehicular and foot traffic clogging every route and intersection. Which is why, no matter the weather, and even though it's essentially a straight uphill climb, my daughter walks to school.

Accessing the school after classes begin is, as I learned last year when dropping off the Dexcom receiver, it's own kind of challenge. I was buzzed through two sets of locked doors and talked with a couple of school personnel, after which my daughter had to run through the nurse's office between classes to pick up the missing item.

So I drove to school, both times, pulling into the drop-off line with my flashers on while she ran out of the building to take things from me through the open car window before the first bell. She was efficient both times, but I imagine the people behind me still looked on with a combination of confusion and irritation.

While the texts may look terse in the photo, my daughter was, in person, both upset she'd forgotten her supplies, and incredibly grateful that I could drop them off. There's a spare meter at school, which she could have grabbed from the nurse's office if she had needed to. But the absence of the Dexcom info she's used to relying on made her uncomfortable, especially in the first week or two of school when the routine is still new and is therefore messing with her blood sugars.

"Phone. Meter. Dexi."

The inventory is now part of our morning farewell routine. If she doesn't say it, I do. One of the perks of our current house is that I, theoretically, should never have to withstand the ordeal of the morning drop-off line. Nobody should have to do so without a child in the car.





via Adventures in Diabetes Parenting

Prophetioc Dreams. Day-by-Day. September 26, 2017

      C.G. Jung stated that there are no prophetic dreams. In his works published between 1916 and 1945he states that dreams are not more 'prophetic' them medical diagnose or weather forecast. Still, as thousands eyes before us we are looking at dreams and try to find out what they mean and what they predict we will face in future.
     More then 40 years ago I had a dream. I just married to man I loved, and I was really happy to have his as my companion for life. There was a dream. My man went to war and got killed. I screamed at night. But when I woke up I just could not understand, why do I have this dream? There is no war. My man cannot be killed on battlefield. The time just regret this dream and get good LOL of it. Not for me. I all the time remembered this dream. Never forgot.
       Time passed. Two our boys were born. One day military man come to our home and he asked for my man that he must come to the military check up. I said, my man does not leave here. He left me with two little one. If he would find him, bring him here and I will cut his eyes. I was so loud that doors started to open. People went out to see what is going on.  Man went out. When my man come home I said to him about that guy, and demanded, no one can open door but me. No one can take any papers, do not speak with any stranger.
       Why it was so important for me that my man does not go to the military office? He went to this office in regular bases, and there were nothing unusual. Not so fast. At this time war was started. Little war, not on our ground. But it were our sins and husbands who must go to meet The Destiny. This was what I did not want. He never was in that office after that, and military man never come back.
       Was it 'prophetic' dream? I do not know. Really I do not care too much about any prophecy. What I do care, to prevent bad things from happening. And I fight.
     As I posted before, it is difficult to relay on someone with any authority and degree of education, that one can read my dreams and say to me what does it mean. But my dreams are very interesting, and I try to remember them
    So, I do have log book of my dreams, Dream Journal. It is personal. It is mine. I do not take care what symbols were used in my dreams and how to find the meaning of those symbols. I am not pro in all those analyses. What I do to keep track of my dreams is to get the meaning what message I got and how to use it. In future posts I will post about different dreams I used to have in past, and how those dreams effected my choices or my life. As I just said, dreams are private, very personal. Dreams cannot be separated from the dreamer and his life. In some dreams we got message we will use many years after we saw this dream. In other dreams it is message what to do right now and how this effect our life in present time. Just listen yourself, let yourself known.

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The Phenomenon of Diabetes Type 2. September 25, 2017

  Fasting blood sugar level. The diagnose of diabetes type 2 based on blood sugar level in different times. One of most common is fasting blood sugar level. What does it mean, fasting blood sugar level? Fasting blood sugar test is a  blood sample will be taken after an overnight fast. Sure it is reliable test? In the diagnose for type 2 diabetes it is stated that food choice effect level of sugar and also it is lead to rick of type 2 diabetes development. So, if it is taken that fasting sugar can be taken as test for diagnose then it is better to say a little bit more about that test then just point out, it is overnight fast. One can eat before bed and then it is fasting level? What if one sleep 10 hours at night? Or 6 hours at night? Level of sugar would be different, right? If so then how it is possible to state diagnose potentially fatal medical condition?
     Activity in blood sugar control. Fasting level of sugar considered to be lowest level of sugar. So, one eat, and then go to sleep. After one awaken  level of sugar in blood would be tested. Why this level of sugar is lowest? That's right, why it is lowest level of sugar in blood? We are, type 2 diabetics , all the time pushed to be active, to go to work out, or at least power walk at least 30 min a day. It is stated that activity will decrease level of sugar in blood. If we are not active level of sugar in our blood going up, right?
     We are not active when we sleep. Our breathing is slow, body temperature and all bio processes go slow. We do not run, do not burn calories. Why level of sugar in blood dropping? Why it is considered that fasting sugar is lowest level of sugar?
     This is really very very simple test, when sugar in blood highest and when it is lowest? How use level of sugar in blood to diagnose diabetes?
      Infections and antibiotic treatment. It is all the time stated that diabetics type 2 do have slow healing wounds, and that we are pron to infections. How often diabetics type 2 tested if we do have infection? When we do have infection, what treatment do we have and for how long? Before treatment with antibiotics stopped do we have any test run to find out if there infection in our bodies? Do we really healthy beside of diabetes? Do diabetics type 2 treated differently when we do have infection or cold or flue, or any other conditions? Really not at all. The same as non-diabetics we are, type 2 diabetics, take limited time of antibiotics medicine, and then no one test if it worked for us or not.
      When we do have infection what organ usually checked out? Lungs. What about pancreas? Does pancreas can get bacteria or virus? Really why not? Only because of this organ never checked up for infection, so with time injection go to canonical stage, inflammation.

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Dreams and Dream Analysis. Apples in Dream. September 25, 2015

In 1900 Sigmund Freud punished his book analysis of dreams. This opened a new era and today Sigmund Freud considered The Father of Psychiatry. His technique to analyze person's behavior   by looking deep inside down to the early childhood, relationship with father, and childhood memories widely used today in treatment mental disorders, even many psychiatrist do not consider him as a valid as it was in past. One of his famous students, C. G. Jung took his banner. He also developed his own interpretation of dreams and created symbols to analyze dreams. I am not so famous in my writings. Still, I do have my way to study, to analyze, and to use all available sources I can have.
       We all do have dreams. We all wish to know what that dream mean for us. This is why many go to Psychologist to get answers to the question, what does it mean what I saw in my dream. In past there were many fortunate readers. I read that books by C.G.Jung and S. Freud and I do not get the general idea, how they interpreter what someone saw in dream and what does it mean for dreamer. In my opinion, dreams are very private. The same symbol may mean so different to different dreamer.
      Apple, one of the most widely seen fruits in our dreams. Apple is associated with Eden, with Sin, and with forbidden desire. I do remember my dream I had long time ago when I was a student of elementary school. I was ill. There was sort of epidemic and we did not went to school in reason do not spread disease. Time passed, everyone recovered, but not me. I turned worse and worse. I am diabetic. I was born diabetic. I all the time was first to get ill and last to recovery. In this time looks like I was not going to get back to life.
      In my dream I was in garden with apple trees. Apples, big, with shiny red side, all around me. And I am dancing in garden. Happy and free. The sky was very blue. The apples were so bright, so shiny, with one side red and shine. I do not remember what color was another side, red, green, or yellow, but one side was red and very shine. I think I was delirium. I think I just wished to have apple. If it was summer then there would not be problem. It was Winter, very cold and frosty. In plase I lived there were no fresh apples. Old lady next house bring apple pie for me, apple jam, and all what did she have. I did not take it. I needed fresh apple, with red shiny side.
     One eve, in twilight my mother put apple in my hand. I opened my eyes, put my teeth in it, and fall asleep. Now I started to recovery. I did not eat apple, I just hold it in my hand. Of cause I ate all of them when I woke up and started to feel better.
      What about that dream? Was it Sin? Or it was erotic desire? Nothing like that. I wish to have apple because of it was almost not possible to get. It was Winter, cold, snow blizzards, and frosty. There were no fresh  apples. My mother got it from somewhere, even it was way too expensive for her. I come back. She needed me. She loved me.
      We see our dreams in different way. Sometimes it mean nothing, just simple reflection of our passed days. In other time it is messages we better do not ignore. And sometimes  our dreams help us to solve our real life problems. It is really very very personal, private.

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Day-by-Day. September 24, 2017

Sugar is good, 105 mg/dl.
        Yesterday I took 280 units of insulin, 20 units less then usual. It is good because of when sugar getting up I have to increase dose of insulin. It is OK, I do not feel really big differences. But it is the signal, my health condition is getting worse. This is why I love when dose of insulin dropping, but the level of sugar still under control.
         I think I do have infection, better to say inflammation. Inflammation is the chronicle condition. With infection we get down very fast, so we take actions such as go to ER or take medicine we do have under hand. With inflammation we do have this condition day after day. we are not really healthy, but still, we are not in critical condition, so we go to work and live our daily life as healthy as we can. Still, it is far away from being healthy life style. With time we have to pay it back, and in higher price. Most dangerous part of this life, ether we are, nether any medical provider take good care for this condition. We cannot do it, we have no education and have no medicine to deal with it. Medical Care does not care because of we are pretty OK and they do not see any need to pay any attention for our condition till it is too late.
         Right now I do have edema, condition when water does no go away. It is also became chronicle condition. So simple, no one provider see it. I am in room with doctor and doctor not able to recognize how loudly I breath. After that I have to do to doctor and say to him what? Really, what I have to say to doctor? Do I have to diagnose myself? Do I have to convince doctor that I do have edema rather then obesity? Edema needs another treatment. Weight loss surgery is not appropriate to treat edema. It is diuretics that usually used to treat edema. They are hardly abused. Finally we develop allergy, and they stop to work for us. Water stay inside and lead to high swelling, obesity. Regardless it is fat or water, bathroom scale will show high number.
       Right now I can have treatment to reduce edema. It is compression devises such as sleeves for legs and arms, even for middle area. This will cost me around $500. Most important, I am not sure it will work.
       I do have wrap roles. They work a little bit. But it is allergy, and skin is very itchy. Also it is difficult to put wrap even, so skin folds and in folds it is extremely painful. I have to take these wraps away. One wrap for two legs cost more then $5. Do the math. I have to wrap my legs and keep them wrapped all the time. As soon as wrap removed I cannot use it second time. I need to use fresh wrap every time. To safe money I simple do not take shower every day as healthy people. I take shower when I need to go outside. Anyway, I cannot take shower by myself.  I need someone who help me.
       At least right now there is no broken skin, and skin is dry. Good progress. No pus running down on the leg.

via Ravenvoron

Metabolic Syndrome. What can we do about it? September 22, 2017

What should I know about  Metabolic Syndrome? Well, at first I wish to ask, why should I know about this syndrome? That's right, why do I have to know about it stand at first, and only after that is Why? should I know about it.

It’s not a single disease, but a group of related health problems: too much belly fat, high triglycerides, cholesterol trouble, high blood pressure, and high blood sugar. When you have at least three of these issues, your chances for heart disease, diabetes, and stroke are higher than they’d be with any of those health problems on their own.

 OK, so what? Do I need to know what is diabetes and how to treat it if I do have high glucose number? What I suppose to do if I do have high cholesterol?  High blood pressure? High TG? Really it is not funny.
      If blood sugar numbers are high then it is better to take insulin.  It is already diabetes regardless if it is metabolic Syndrome or not.
      If blood pressure is high then it is better to take actions right away to prevent stroke. It is not that stroke is a chance. It is follow up to high blood pressure if it left not treated. BTW, when blood pressure is high it is severe pain, and do we want it or not we take all medicine we are lucky to have handy, and swallow it. So, what it has to do with so funny disease such as Metabolic Syndrome? Nothing. If blood pressure is too high, go to ER or call 911. It can safe at least tax payers money.
      High TG is already result of heart disease, and better to see a doctor right away. There is only one problem, doctors usually do not see high TG. They usually see pounds on bathroom scale. Then they present that high TG is result of poor diet, only poor diet. Nothing more that behavior misconduct.
       So, now, if we do have Metabolic Syndrome then what after being diagnosed with this condition? Is there some treatment for it? Really, what we suppose to do if in addition to diabetes, high blood pressure and high TG I do have Metabolic Syndrome? Is there some treatment  for this condition? No. There is nothing, as far as I do know it. If so, then why do Metabolic Syndrome diagnosed?
      It is very simple. If one has Metabolic Syndrome then one  "get chance to get diabetes, stroke, or MI" So, in this moment there is no need to treat diabetes type 2. It is not diabetes at all. It is Metabolic Syndrome, not diabetes. The same as it is with MI and stroke. To diagnose stroke MRI must confirm there is stroke. Also there probably some chemicals in blood. I have no one idea how stroke diagnosed. I never was diagnosed that I have stroke or MI. I even do not have diabetes type 2. It is Metabolic Syndrome, not diabetes yet. Funny. But not for me.

High TG. It’s a type of fat in the blood that your body makes from extra calories. If you can’t keep your level below 150 mg/dL, you could be more likely to get metabolic syndrome. You can take medicine to lower your triglyceride levels, but the best way is to lose weight, exercise, and cut back on calories.

Easy to say, hard to believe. If my TG level jump from 700 mg/dl up to 900 mg/dl just withing less then one month then say me, why it is this month I suddenly started to take so many extra calories? When insulin supply was restored and insulin was delivered to my home withing month TG dropped back to 700 mg/dl. Now it is normal level  of TG because of my blood sugar under tight control. No any difference in calories intake. Medical Scam.

HDL is “good” cholesterol that may help remove LDL, the “bad” kind, from your arteries. If your HDL is less than 50 mg/dL for a woman, or less than 40 mg/dL for a man, that can set you up for metabolic syndrome. You may be able to raise your HDL levels with weight loss, a better diet, and other lifestyle changes.

 Looks like weight loss so universal that it will:
      reverse diabetes type 2, 95 % of out of 30 millions of Americans will be diabetes free only if we lose weight;
       increase HDL and decrease LDL at the same time;
       bring high TG down from 900 mg/dl to 150 mg/dl;
of cause, no high blood pressure, no high mortality from stroke and CVD. Simple, lose weight, and there are no any problems, right?

High Fasting blood sugar.  When you don’t eat for 8 hours or so, your body begins to run out of blood sugar from food and it starts to break down the stored form. Your body uses the hormone insulin to keep levels in a healthy range. But sometimes it can’t manage this balancing act and your “fasting” blood sugar gets too high. Anything over 100 mg/dL could lead to metabolic syndrome.

I cannot believe it is medical journal.There is no one comment. SCAM!!!!!!!! Author has no one idea what one is talking about. Just read it, they said it all. No any comments needed.

Blood pressure is the force of blood pushing against your arteries as your heart pumps and rests. If yours is higher than 130/85, you could get metabolic syndrome. But you may be able to cut your numbers naturally if you lose just 5% of your body weight. Exercise, quitting smoking, and a healthy, low-salt diet can also help.

Quite smoking is most important. If you never smoke it is even harder to quite. BTW, why believe you never smoke?

You’re more likely to get it as you get older, and you also may have some genes that raise your odds. There’s not much you can do about that. But you can make other changes to prevent the condition and lower the chances you’ll get coronary heart disease, heart attacks, and type 2 diabetes.

One question , please. It was told that to have Metabolic Syndrome we have to have three conditions at the same time. So, how can I prevent Metabolic Syndrome? By trying to prevent all symptoms all together? Well, it is nice that to do so all what I do need just lose weight.  All the time lose weight. Never stopping process. Loos 10 pounds, go for another 10, go for 20, 30, 40 ..... 100, 900, and so on. Just lose all what you do have. We really do not need Hospitals. Crematoriums would be more effective. At leas there we lost more weight, all weight, and no diabetes type 2.
 
 What You Should Know About Metabolic Syndrome   http://ift.tt/2wELTt6

via Ravenvoron

One Weight-Loss Surgery Shows Lasting Results

Patients 77 pounds slimmer on average 12 years after gastric bypass, study finds

Source: HealthDay


via Diabetes

Fracture Risk Higher for Seniors with Diabetes

Bone weaknesses seen in those with blood sugar disease

Source: HealthDay


via Diabetes

Eat or do not eat? September 20, 2017

Blaming excess weight on people simply not changing their eating habits goes back thousands of years. Sloth and gluttony are two of the seven deadly sins, after all.
 'Eat Less, Exercise More' Isn't the Answer for Weight Loss by Alexandra Sufferin

http://ift.tt/2wyeMau

      Really very interesting. Why it is sin to be obese? Low weight, the same as high weight are the same. It is result of health problem. People who are sick or ill lose weight or gain weight, if they still able to fight for their lives.  In some cases we lose weight even we do not want it, became skeletons, skin and bones. In other cases we gain weight and became Giants. Another point about weight is that now people grow. Our children taller then we are, and grandchildren even more tall. So, why it is weight we have to cut according to standard of 1850? Let us take a look at how  long people now compare with 1850, and cut them off. Why not?
       'Sloth and gluttony' is not about those who does not have access to meal. It is referred to wealthy people. But it is poor whose life all the time shorter then those with wealth and power. Poor work for food, and there is no one way they can be sloth. Also there are many studies that confirm, blue collar workers have wider middle area, more aggressive diabetes type 2, and die due to diabetes, stroke, or heart attack timelessly.  Wealthy people who have time to relax, to eat what they want in the time they want, and do nothing if they want, live longer and healthier. Elizabeth Hughes was able to survive on Starvation diet and then was first American who started to take insulin injections. The question is, how many other children die in America diagnosed with diabetes at the same time as Elizabeth?
        Excess weight is this really eating habit? How separate water, edema, and fat according to the number on bathroom scale? No answer. Just lose weight, and no diabetes type 2, Freedom! In present time diuretics are the most effective way to keep pounds away. For how long? Diuretics effect kidney and heart, and lead to other health issue. With time diuretics stop to work, so all pound that were lost by using diuretics, returned. All the time with PLUS.

Refined carbohydrates spike insulin levels. Insulin, as Ludwig (Ludwig and Dr. Mark L. Friedman of the Nutrition Science Initiative in San Diego) describes, is the granddaddy of anabolic hormones. Basically, when you eat a lot of refined carbs, like say, a 100-calorie pack of Oreos, it causes a surge of insulin that will trigger your fat cells to soak up calories—but there are not enough calories and nutrients to provide the energy that our bodies need. The brain recognizes this discrepancy and triggers a hunger response that also slows our metabolism. We are then going to want to eat more.

     I am lost. What really does it mean, 'spike insulin level'? Did they took some test to see that 'insulin spike'?  Never. This is just cheap speculation, and they do know it. What they do not know is that today we do not need little one to say: "King Is Naked". We can say it without fear of King. Yes, Ludwig and Dr. Mark L. Your King Is Naked!!!!!!!!!!!! No longer you can sell this crap.  Not so many people trust in you regardless of all your titles.
      As I do remember so far carbs spike sugar in blood. If it will spike insulin level then it is fine. But there is the problem. There is no insulin, so sugar from carbs stay out of place where it suppose to go. We are hungry. Then more we eat then more hungry we are.  Paradox? Phenomenon? Not at all. There is no spike in insulin level. Add insulin in injection and hunger would go away. Old fashioned well known treatment for all types of diabetes. Universal Treatment. With insulin hunger does not take over, and we do not want to eat extra calories. We simple do not wont to eat. We are full. We are not hungry. Obesity stopped. So, human livestock supply stopped too. Diabetics get out of hook.
      Without insulin we stay hungry, does not matter what do we eat or how much do we eat. Fatty meal help curb hunger faster then any other food. This is why in my ref it is all the  time smoked salami. A few rings of it will give me more then any glucose in IV.
      Let us take a look what doctors said.
     They said we have to count calories, to decrease input down to 1600 for women. There are lists what to eat, and full plate for morning and eve, Summer and Winter, sick days or vacation week. Now it is another directions, stop to count calories. It is also doctors recommendations. So, what I suppose to do? Eat or do not eat? So simple, 'Yes' or 'No'?
      Still, I do not have answer what to do with edema, water retention? How water retention is my biggest problem. Maybe one day Time would publish how fight edema? The stigma ' eat less work out more' does not work for ill people. We simple have bigger Fish to Fry.

via Ravenvoron

Diabetes & A 49 Blood Sugar That Sneaks Up Like A Bitch Ninja

It was a morning of trying to plow through, 
taking notes for an article I'm working on, two deadlines looming on the calendar, and doing my best to stop the Graham Cassidy insanity from happening. 
Focusing on getting shit accomplished. 
And out of nowhere, I suddenly felt shaky and tingly all rolled into one. 
I was sweaty and hungry and I didn't feel so steady on my feet. 
Diabetes had snuck up on me like a bitch Ninja and I was dropping fast. 
Status: Threat level Hot Mess, with a blood sugar of 49. 
I grabbed a juice-box, sucked it down, and immediately sucked down a second.
10 minutes went by and I ate 7 Swedish fish from the movie size box in my computer bag. 
The box of Swedish Fish I bought for 99 cents and on sale last week - and I don't even know why I'm mentioning that, but I am. 
Sidebar: Swedish Fish are now much smaller than they used to be. WEIRD. 
5 minutes earlier I was sitting at my computer and everything was fine.

Now? Not so much. 
I did my best not to overeat - easier said then done.
I watched the clock and tried my best to wait before treating again.   
20 minutes later my blood sugar was 95 and I let out a deep breath.
I fiddled with the InstaMessage App for a few, (see above pic,) and 15 minutes later I checked my blood sugar again. 
I was 142. 
A small correction bolus was given - what had gone dangerously low, was now on its way towards the cheap seats. 
Current Status: Blood sugar is172 with 1 unit of IOB. 
Pod PDM suggests I give myself a 0.30 correction. 
For now I'm holding off. 
Back to work - but a quick blog post because this is life with diabetes - and I continue to plow through. 




via Diabetesaliciousness

Back to School Year #13

My daughter went back to school this month- for the 13th time if we include the preschool years. It's still never easy.

Back to school is a challenge for most kids. There are difficult teachers, tough social situations, and strict schedules to keep.  But for my kid and many like her, fall's biggest stumbling block is diabetes.

The back-to-school diabetes problems are ever-present, but not always the same. Some years there's a new nurse who we have to meet and coordinate with. Some years there's a new activity which coincides with the start of school, adding another diabetes thing to think about. Some years the time of lunch has changed (like the 'year of brunch,' linked for you here though I'm going to choose not to reread and relive the horror). Some years gym proves to be a seemingly insurmountable obstacle (like last year, when at some points it was simultaneously terrifying and ridiculous). Some years there's a teacher who just doesn't quite get it. Or one who's extra nervous. This year we've added a daily walk to school, just a couple of blocks but most of it straight uphill.

There's one back-to-school diabetes challenge that's constant from year to year: the overall change in the daily schedule. August is lazy- featuring vacation, the backyard, books, friends and the pool. For the past couple of years August has also included sleeping late at least a few days a week, and alternate sedentary stretches of binge-watching Netflix and power-finishing summer homework. Going from a slow, sedentary start to 6:30 a.m. breakfast followed by a brisk walk to school would be a jolt to anyone's system. Adding diabetes requires an annual investment in juice boxes and a lot of dosage tweaking.

By the fourth day of school this year we'd already changed the breakfast bolus ratio and several basal rates. Twice.  And she was still eating glucose tabs every day half an hour before lunch. We've gotten that to the point where she's usually just barely 80 at lunchtime but then shooting way up into the high 200's late in the day- except when she has marching band in which case she's staying steady and then tanking overnight. We will not discuss what the weekend numbers look like with an ever-changing band/homework/fun/sleep schedule.

Every year kids face challenges going back to school, diabetes-related or otherwise. They come home and tell their parents, who provide any number of phrases to soothe them: This too shall pass. What doesn't kill you makes you stronger. Life's too short to worry about that. Just do your best. And so we'll continue to apply these same pithy phrases to our approach to managing the back-to-school diabetes adjustment. We'll do our best, making tweaks every couple of days, trying not to worry, knowing that we will get through this, stronger in the end, as we always do.








via Adventures in Diabetes Parenting

Day-by-Day. September 20, 2017

Sugar is 67 early in the morning. Low blood sugar.
        I used to have 40 mg/dl. Still it does not change the fact that today sugar is low and I feel very very sick. I even was not able to get something to eat. I usually do have all around me in my house in case I am low so I can grab something and eat right away. So, I took cappuccino, still low. I took another bottle of cappuccino, and still low. I eat, and does not get better. I needed something hot like soup, but I am alone at home, and I could not get to kitchen. In addition to low it was severe headache. I noted, I cannot think clearly. Lungs are noisy. Difficult to breath.
       Best way in situation like this is to go to bed and try to get some sleep. I did. I staied in bed till my man come home and fixed something to eat for me.
      I do not fight pounds. I am not in war with myself. It is easy to say, we all diabetics type 2 able to fix our pancreas with starvation diet. I am out of this hook now. I simple do not trust in any doctor. They are not scientists, they are businessmen.  If they are able to get penny from every one of us, diabetic type 2, then it is 30 millions. Good money, right? 30 millions, and only one penny from every one of us, good deal for every one of them. This is why they spread humors and myths that we did it for ourselves.
       Today my man wrapped both my legs, and left arm. It is all the time with left site. In my 40ths I had my first stroke. Left site was paralyzed. Now so heavy, so I still working. Now left site is weaker then right site. It is rush on the arm as it started on leg, also left, and then on the hand, also left. So now it is arm, left arm.
      My kidney looks like got inflammation. It was infection in Summer, but as usual, there is no any treatment. Now it is not infection in acute stage, but inflammation, chronicle state. What doctor said? As usual, I have to lose weight. What else they can say? As usual, they Rx Healthy Life Style to all ill and sick people, and we cannot follow doctor's order. So, we stay ill and sick, and this is how we all did it for ourselves.  Just think about, 30 millions of Americans are diabetics, people who do not chose healthy eating and couch potatoes. 80, 000 us die every year. It is 100% preventable cut of lives. But who will fight these deaths? We are with running and healthy eating? Sorry guys, it does not work for diabetics. Simple, it does not work.
      It is humor that in America there are too many hate. I do not think it is only in America. How many diabetics around the globe? Do they have respect? Do they have insulin to fight for life? Not at all. WHO presented, it is diabetes type 2, and diabetes type 2 is number 7 cause of death around the globe. So, when someone say, it is hate in America, simple look around. Is this really true that it is only in America immigrants have health care, and those who paid to Medicaid cannot have it because of we do not belong to  low  income families? Immigrants come to America and have all, Medicaid, Medicare, low rent, SSI, and so so on. Are they idiot to work? Why do they need it? They already do have all what they need. Paradise. What Americans do have?
     My man lost his job. Unemployment check was $1348 for two of us. Insulin cost $2000 monthly. Cut for to be 'low income' was $1100. Woman next door who worked no one day in America, and she even does not live in NYC. But NYC pay rent for her, Medicaid,  medical transport, home aid, and SSI. Now my man got the job, and company has health plan, so I do have insulin in my ref. I have to pay 11,000 to SSA. I am typical American. One of 30 millions diabetics.

via Ravenvoron

supply of human livestock for medical industry. september 19, 2017

Over the years, researchers have noticed that many patients suffer from both type 2 diabetes and chronic inflammation. Chronic inflammation is caused by many factors, including aging, obesity, and high sugar consumption. These factors also increase the risk of diabetes.
http://ift.tt/2f8ttpE

       Simple and brilliant! 30 millions suffer from diabetes in America.  80,000 people die every year due to diabetes, 100% treatable medical condition. And what? It is age, obesity, and high sugar consumption. Probably yes, I have no evidence to fight this abuse of millions Americans. Millions! Remember, it was also presented that people who died from TB were "consumed". Before TB was discovered the medical condition was named "consumption". At that stage people were skinny, underweight. Now it is another problem. People are obese. This is why we do have diabetes type 2. Really?

 Diabetes is characterised by a deficiency of insulin. The opposite is the case in congenital hyperinsulinism: patients produce the hormone too frequently and in excessive quantities, even if they haven't eaten any carbohydrates. Since the function of insulin is to metabolise sugars, excess production of insulin leads to chronic hypoglycaemia. The brain, which devours vast quantities of energy, is perpetually undernourished. http://ift.tt/2w4l1yA

       This problem come from where? How this condition treated? By removing infant pancreas. No one do know where problem come from, but it is healthy well working pancreas which would be removed. In infant. Is this really the solution? Hard to believe.
      I posted many times, diabetes is no longer medical problem. It is social. Now with so many types of insulin available to treat diabetes, diabetics diagnosed with mystery of diabetes type 2, even little one, as little as 6  or 2 years old. The treatment for type 2 diabetes is all but insulin. The result is, disability, timeless death, and hyperinsulinism in infants.   
     What is the treatment for diabetics type 2? It is  95% of diabetics population. Mostly SU, medicine which effect diabetic pancreas to secret more insulin. Then woman get pregnant, and what? her baby would have hyperinsulinimia. There is nothing about pathology. It is wrong treatment which mother or father got before pregnancy. Treated with insulin diabetes will go to the decline. Treated with SU it leads to develop many other condition, but never to the recovery, healing. Constant supply of human livestock for medical industry.
       Why in infant it is insulin overproduction? Why it is not under nutrition? Probably in stead of to remove baby's pancreas baby must have meal more often then baby born to non diabetic mother or father?  It is all the time presented that when diabetic has low blood sugar it is resulted by high insulin in blood, and it is not. It is low nutrition. Cup of soup will solve the problem. In stead diabetic given glucose, and it leads to high blood sugar. Treatment like that in infant will lead to damage of brain, and even to the Death of newborn. Where this diagnose come from? How it was diagnosed that infant's blood overloaded with insulin? Still, it is diabetes, mystery all the time.

The inflammatory response can be provoked by physical, chemical, and biologic agents, including mechanical trauma, exposure to excessive amounts of sunlight, x-rays and radioactive materials, corrosive chemicals, extremes of heat and cold, or by infectious agents such as bacteria, viruses, and other pathogenic microorganisms. Although these infectious agents can produce inflammation, infection and inflammation are not synonymous.

This is definition from the medical dictionary. Most famous diabetic, Elizabeth Hughes was born healthy child. Her diabetes was result of Influenza. Insulin saved her life. Today Influenza is not so devastated. There is no devastated death due to TB. Many other medical condition successfully treated. we live longer. If so then why it is obesity or super consumption of sugar lead to development of diabetes? Maybe it is diabetes leads to obesity?
      I am not going to investigate where is a tail and what is the head. It is not really important. The important part is, diabetes type 2 can be effectively treated with insulin. Diabetes cannot be prevented, but it can be diagnosed early if level of sugar in blood would be vital. And for prevention of diabetes every infant have vaccine to prevent endocrinology disease. Look at the diagnose.

Diabetes occurs when the body cannot metabolize glucose properly. Normally, the hormone insulin breaks down glucose. But in some people this process becomes increasingly inefficient, a phenomenon known as insulin resistance.

What authors are talking about? Why the process is inefficient?  Insulin do the job. Insulin resistance is simple next stage after acute diabetes. It is condition when insulin still be secreted by diabetic pancreas but in very insufficient amount. Add insulin in injections, and the recovery will take off. In stead diabetic's pancreas flogged with SU and slow die. It takes years. This is why diabetes type 2 number 7 cause of death. It takes less then 10 years of treatment after diabetes type 2 diagnose. In contrary diabetics type 1 live over 60 years after being diagnosed with diabetes, and they do not bring up infant with hyperinsulinia. It is a new phenomenon, result of diabetes type 2 diagnose and treatment with SU. 

via Ravenvoron

Possible Cures for Type-1 in the News (September)

Catching Up With NNC0114­-0006 (Anti IL-21)

Back in 2015 Novo-Norsk started a clinical trial into a combo treatment of NNC0114-0006 and Liraglutide (which is more commonly known as Victoza).  I ignored this trial, because I thought that NNC0114-0006 was a new form of insulin, and they were testing a treatment for type-1 diabetes. However, I have since found out that NNC0114-0006 targets IL-21 and that Liraglutide may stimulate beta cell growth.  Therefore, this combination could have the effect of stopping the autoimmune attack while at the same time regrowing beta cells, and that would be a path to a cure.

Liraglutide is approved for use in type-2 diabetes and works by increasing insulin production. Recently, experiments in mice have suggested that it works (at least partly) by helping the body grow more beta cells, and preventing the death of beta cells:
http://ift.tt/2jFmFEQ

NNC0114-0006 is an anti IL-21 treatment.  IL-21 is a chemical that the immune system uses for communication, and several experiments have suggested that too much IL-21 is important to creating type-1 diabetes:
http://ift.tt/2xiaO4D
http://ift.tt/2jGSjBR
http://ift.tt/2xickUm
(and there are many more such studies.)

So combining these two treatments provides a possible path to a cure.

The Current Study

The study that started in 2015 is a phase-II? trial (the question mark means that it is a phase-II trial, but there has never been a phase-I trial for this combination of treatments).  The basic study design is four groups: one group gets both treatments, one group gets two placebos, one group gets NNC0114-0006 and placebo, and one group gets Liraglutide and a placebo.  So they have all their bases covered. The study is large: 304 people recruited from 100+ sites all over the US and Europe.

The clinical trial record says that this study is recruiting patients.  However, when I look at the list of locations, every one is marked "Active, not recruiting", "Completed", or "Suspended", so I'm very hopeful that they have recruited all the patients that they need.  That is important, because they expect to collect data for 80 weeks.  Their target completion date is April 2019.

This is actually the fifth study of NNC0114­-0006.  You can see the list here:
http://ift.tt/2jHN2KD
The four previous studies were smaller (between 10 and 65 people), and were done on other autoimmune diseases: Rheumatoid Arthritis, Crohn's Disease, and Systemic Lupus Erythematosus.

Clinical Trial Registry: http://ift.tt/2xhvvxi
Other Study ID Numbers: NN9828-4150
2014-001215-39 ( EudraCT Number )
U1111-1154-7172 ( Other Identifier: WHO )
REec-2015-1768 ( Registry Identifier: Spanish registry )

Metreleptin Fails A Phase-I Trial

Back in the 2008-2010 timeframe there was some hope that Leptin would cure type-1 diabetes, and a clinical trial was started in 2010.  Then in 2015 the trial was canceled by one of the sponsors.  Finally, now in 2017 the results have been published, and the conclusions are:

Metreleptin is safe but may not be efficacious in improving glycemic control in patients with T1DM, although it reduces body weight and daily insulin dose modestly.

You can read my previous blogging here:
http://ift.tt/2fs7uYI
The abstract is here: http://ift.tt/2xhvwBm
Clinical Trial Record: http://ift.tt/2jGbbBf

Interesting Treatment for Multiple Sclerosis

I usually do not blog on cures or treatments for other diseases.  However, MS, type-1 diabetes and several other diseases are all from the same family of "autoimmune diseases".  They are all caused by the body's immune system attacking a different organ or internal system.  So in theory, research into curing one of these diseases might help cure the others.

So with that in mind, I thought this study was interesting:
Multiple Sclerosis Therapy NKTR-358 Begins Phase 1 Clinical Trial:

Basically, this company has a treatment which causes a person to generate more Treg cells.  Since Treg cells regulate the immune system, having more of them might prevent the immune system from attacking the wrong cells.  In type-1 diabetes, we have several research programs aimed at increasing Treg counts, but usually by growing more Tregs outside the body, and then infusing them into the body (T-Rex, Stem Cell Educator, and Stem Cells of Arabia are all working on similar ideas). NKTR-358 is a treatment which (they hope) will cause the body to generate more Treg cells, itself.

Also, NKTR-358 works at least partially, by targeting the IL-2 receptor in the immune system, and this receptor is also an active target of research in type-1:
http://ift.tt/2km1GmI
(and the IL-2 targeted by NKTR-358 is different than the IL-21 targeted by NNC0114-0006 above.)

Company Information: http://ift.tt/2xhvx8o
Some animal data: http://ift.tt/2tGge9g

Joshua Levy
http://ift.tt/2fs7dVR;
publicjoshualevy at gmail dot com 
All the views expressed here are those of Joshua Levy, and nothing here is official JDRF or JDCA news, views, policies or opinions. My daughter has type-1 diabetes and participates in clinical trials, which might be discussed here. My blog contains a more complete non-conflict of interest statement. Thanks to everyone who helps with the blog.


via Cure Research

Why Diabetics type 2 do avod insulin? September 18, 2017

      The insulin therapy is out of the question for diabetics type 1. As soon as diabetic diagnosed with type 1 diabetes, insulin started and it is assumed, diabetic will take it for the rest of one life. It is very different with diabetics type 2, 95% of diabetics population. Why it is so? In my last post from September 17, 2017 I gave link to the article that 30% of diabetics type 2 avoid insulin when it is recommended, but still, take insulin about two years later. Why it is so?
      When I get box of needles for insulin pen I do have instructions how to use these needles, and it is very long instruction, very detailed. Every box of insulin come with instructions, how to us, to inject insulin. There is no instructions, what dose of insulin to inject. All the time we told, diabetics are all unique, so dose of insulin, timing, and type of insulin unique for every diabetic. Is this really true? Not at all.There are millions of diabetics. Is this possible to create unique pattern for every one of us? Really, it is not, and it is easy to see. If so, then why dose of insulin never defined? It is easy to hide behind unique personality. Still, why the dose of insulin defined for type 1 diabetics, and there is no dose for diabetics type 2?
       When I started insulin and injected my first 11 units I was diagnosed with diabetes type 2 about ten years, and my fasting sugar was around 400 mg/dl. I got box on insulin as diabetic type 2 outside of clinic as study how insulin can be effective to treat diabetic type 2. I was instructed to add three units every three days if sugar is above the target. When dose of insulin overdo 20 units, and it happened withing one or two weeks,  ... well, I had no insulin and I was out of study. Why 20 units is the limit for diabetic type 2? Later I finally find out diabetes type 2, insulin resistance, what is it? It is the type of diabetes when diabetic need more then 200 units of insulin. Ten years of being diagnosed with diabetes type 2 I never had any insulin injection. No one doctor's recommendation, and even no one info and idea how to deal with low blood sugar or how to check up urine for ketones. Simple, diabetics do not have it. If we do not have it then what is the reason to check it? If test never run then how it was found that diabetics type 2 do not have it?
      The dose of insulin counted by med pro depend of how many calories or carbs diabetic going to eat.  At the same time one of the biggest problem with insulin therapy is low blood sugar. How low blood sugar suppose to be reversed? With carbs, two spoons of sugar, or sweets, and so on. Now the question is, how count dose of insulin if insulin leads to low blood sugar? If one take less carbs then it is in demand to cover high blood sugar then diabetic get down to low blood sugar. Swings. The result of all those calculations, no one can define, how to dose insulin.
      To add odds to the drama, the type of insulin plays significant role. Rapid acting or short acting type of insulin is not the same as long acting insulin. At the same time when diabetic finally find out how med pro count dose of insulin, it is W (weight in pounds) :4= U (units of insulin) to inject. Now there are type of insulin, Bolus or Basal.  U = Bo +Bs. U is dose of insulin taken daily, 50% Bo + 50% Bs. Is this really possible to work? It is not. So, every diabetic confused, what one must to do? If med pro have no one idea how to initiate insulin therapy then say me, how diabetic can use insulin? The absurd of all math in insulin dosing very easy to see if mind is open. Every one diabetic who take insulin do know very well, basal insulin and Bolus insulin cannot be taken in the same amount. But according to the med pro formula, B0 = Bs. Yes, it can be said, Bo = 60% and Bs = 40%  or voce versa. Still, it is wrong treatment and it never works.
      After a few days or month riding on High - Low Swings, diabetics type 2 usually give up.Low sugar can put in coma just withing day. High blood sugar needs more time. Time is crucial for us. We take better perspective to survive.      

via Ravenvoron

Diabetes type 2 insulin therapy initiation. September 17, 2017

Thirty percent of type 2 diabetic patients don't begin insulin when it's initially recommended, with the average start time being two years later.
http://ift.tt/2jzRMle

•  Why? Why diabetics type 2 do not start insulin therapy when it is recommended by doctor? 
• Why two years later diabetics type 2 start to take insulin therapy? The same diabetics who did not accept insulin in first place, take insulin two years later? 
• To what diabetics insulin therapy was recommended by doctors, and when it happened, on what time of diabetes development?

It is easy to read this statement by med pro and accept that good doctor recommended to diabetic to start insulin therapy, but patient so resistant, they do not do what doctor recommended to them to do. At the same time it is only 30% of diabetics type 2 who resist insulin therapy when doctor recommended it to them. 70 % what about? Were they recommended insulin therapy and started to take insulin shots? Or 70% of diabetics type 2 still fighting Big Numbers with Life Style Modification? Good question, is not it?

"Unfortunately this isn't uncommon, patients being reluctant to start insulin therapy when it's recommended," says Turchin (Alexander Turchin, MD, MS, director of quality in diabetes in the division of endocrinology, diabetes and hypertension at BWH).  "Many clinicians have encountered this phenomenon, but until our study it was not known just how prevalent delays in insulin initiation are. As physicians, we need to make sure that these patients are making fully informed decisions and that we understand their perspective to ensure they are treated effectively."

       Effectiveness of diabetes type 2 treatment? Really, what they are all talking about? Diabetes type 2 is number 7 cause of Death in America, why? Because of there is no diagnose for diabetes type 2. There is no definition of diabetes type 2. There is no one test to diagnose diabetes type 2. Well, yes, it is sugar in blood, that's right. But if high temperature of body lead to diagnose of phemonia? Not at all. It is X-ray of lungs must be done to see if there is problem in lungs, or the inflammation in some another place. It is different with diabetes. Doctor take measurement of muddle area, or put victim on bathroom scale, and there we are, diabetes type 2, resulted by high obesity. At the same time millions of diabetics type 2 walk around USA without being diagnosed with diabetes, and collect pounds they never able to get rid off. Really, before diabetes type 2 started was diabetic fit or obese? No clue. But the stamp is already humped on the victim, diabetic type 2 developed diabetes because of wrong life style. After that they ensure us, we are treated effectively. Sorry, I do not buy this crap.
       Why really diabetics who has choice to take insulin or glipizide, take pill rather then injection?
      Well, remember, insulin lead to weight gain. No one wish to get extra 100 pounds around middle area. So, diabetic refuse to inject insulin. Really, weight gain is myth. We gain weight not because of we take insulin but because of many underling conditions accompany diabetes type 2, long standing endocrine disorder which started long before sugar appeared in blood. Actually, to my big surprise, insulin reduce weight. Why? It is another story to the another post.
      How diabetic type 2 suppose to take insulin? I do not mean how to put needle in the site and that site must be rotated. Any nurse or even in every box of needles there is instructions how to inject insulin, to administer insulin. The real problem with insulin therapy is dose of insulin, type of insulin, and timing. If we take a look at the any med pro publications how to initiate insulin, there are all about, but never really suggest how to count dose of insulin according to the real blood sugar number. There is no dose of insulin, how to find out what dose to inject. It is really too complicated for med pro. And now those who has no one idea how job to do must recommend insulin therapy to the victims. No question, they do their best to prevent diabetic from initiating insulin injections.
      Let us take a look at the education programs, how our educators suggest to deal with low blood sugar? Eat some hard candy, two spoon of sugar, soda, or something else like that. It seems to me they have no one idea what they are talking about. It is not big surprise that diabetics in hospitals die because of low blood sugar. Two spoons of sugar lead to crush. It can probably rise sugar in blood, I never checked up my sugar at that time. The problem is, it doe not heal. Simple, there is no any help with those two spoons of sugar. I still shaken, and hardly able to breath. No move to avoid to collapse. It is not fanny, trust me. Usually we fall face down. It is black out.
     I never was in ER with low blood sugar. But there are records, I used to be, why? Because with my insulin dose 300 units daily it is easy to put diagnose: Low Blood Sugar, and kick me off after a few hours. Simple. Safe for ED. In hospital they give IV with glucose. Body system get overloaded with sugar. Swing go up and down.
     In contrary with med pro I simple inject insulin, long acting lantus solo star when sugar is low before my first bite. The result? No extreme hunger. If I do have chance to get some sleep it is best to recovery. It is really very unusual to take insulin injection in case of low sugar before first bite. But it perfectly work. Do not assume that if sugar in low then insulin is high. It is not the case. The sugar is ;low, and insulin is low, this is common scenario in case of insulin therapy.

via Ravenvoron

Increasing Salt Intake Tied to Diabetes Risk

Odds of both type 2 and latent autoimmune diabetes rose when adults consumed more salt, study shows

Source: HealthDay


via Diabetes

Could Artificial Sweeteners Raise Your Diabetes Risk?

Small study suggests these products might somehow inhibit blood sugar control

Source: HealthDay


via Diabetes

Diabetes type 2. What insulin is best? September 15, 2017

     According to all guidance med pro give to diabetics, type of insulin we have to chose depend on age and ... how often we check up blood sugar level; what is our goal and  .... what do we eat. How any of these recommendations can effect what type of insulin to chose? Simple, it does not effect. Regardless of my age Lantus Solo Star is good for me. This insulin take all diabetics type 1, children including. So, age is not the mark to chose type of insulin.
     Goal? To keep blood sugar under tight control. It does not mean that at any time my blood sugar is within normal range. It is simple not possible because of I am diabetic and I do take insulin in injections because of my endocrine system does not secret insulin in amount my body system needs for healthy function. Still, my goal is all the time to keep blood sugar level under tight control, as close to the healthy normal as it is possible.
      What do I eat? How this effect the type of insulin I have to chose? Well, it is another problem. Why do I need to chose type of insulin in regard what do I eat? Simple. They all the time present, we have to count carbs because of it effect our level of sugar. Now there is another twist, I have to chose type of insulin in regard what do I eat.  It is interesting, is not it? Usually we do not pay too much attention what we told. But I am stubborn. I take all under my attention and I wish to ask doctor, why type of insulin depend on what do I eat? At the same time I have to eat according to the diabetes treatment. Really, I lost, do I have to chose what to eat, or I have to choose type of insulin which is best for me?
      To make story short, I do not pay too much attention to this crap. I pay very close attention how my numbers on my personal meter go up and down. This is why when doctor changed Lantus Solo Star to the another type of insulin, Toujeo, I noted very fast, this is not my type. My numbers go up. Dose of insulin go up. Really I did not have that I had sort of allergy. And right now I do not remember what really did I feel at that time. But it was not good, and I did not want my numbers out of my control. So, I returned to old trusted Lantus Solo Star.
     With Lantus Solo Star my numbers go up and down. When someone pretend they do have the same number day after day because of they eat right, it is not true, it is scam. If one does not have diabetes then it is true, numbers stay in the range all the time regardless of what one eat. If one is diabetic then regardless how hard we try to keep sugar under control, numbers never the same day after day.
      Another point, someone may say, they cured diabetes type 2 for 11 days, three months, and so so on. Scam. It is not possible. Even with insulin and tight control it is not possible to cure diabetes within 11 days or three month. Why? Diabetes started long before numbers on meter went up and diabetes was diagnosed. This mean that the endocrine system disorder already effected all body systems. Our vision got worse. Skin darkened and brown spots show up on the face and other part of body, legs usually. It effected our heart and out lungs, our kidneys and our liver, any tissue we do have already effected long before diabetes type 2 diagnosed. So, to fix the problem, it takes long time to heal heavily effected pancreas. far longer then 11 days or three month.
        Final mark what type of insulin chose is, how my body react on insulin. This part takes time. At first we trust in doctor because simple we have no one idea what insulin will do. Then it comes own experience, and it is time when we are ready to make our choice. I tried many times to take both, rapid actin and long actin insulin. It put me on high - low swing, and I do not like it. I stopped all types of short acting, rapid actin, or intermediate insulin, and take only one type, long acting pre-mixed Lantus solo Star.      

via Ravenvoron

Diabetes type 2 and insulin. Memory. September 14, 2017

       It is an American custom to present the people with familiar faces, celebrities, and what they said or done in situation we face. It is important in election, presumed we will follow our leaders with millions income. So do with diabetes. Celebrities with diabetes show up on shows and share what they eat and how they are suffered till they curb carbs and sugars. Not they are diabetes free or happy and manage diabetes which did not stop them.
       It is easy to be rich and celebrity. I am not one of them. I am 'simple'. No one do know my face. I am one of this millions who went not diagnosed with diabetes and lived year after year trying to get better with workouts and starvation. Nothing worked. Finally, there no health insurance, no medicine, no income, and I am not capable to work. Typical situation all 'simple' Americans face.
     In 2011 first time I injected insulin in my belly. It was just 11 units. I got my insulin pen as a participant of some studies. Studies studied how insulin effect diabetics type 2 and if it can be used as therapy. The point was, start from low dose, and then increase dose by 3 units every three days if sugar still going up. If sugar is normal, stay on this dose. If sugar is down, decrease dose by 3 units.
      So, I did. Every three days I increased dose of insulin by three units and soon ... I was out of study. I hit limit, 20 units a day, and my sugar still going up and up. There were no any explanation to me, nothing, no any $ paid that I participated in studies. But they demanded I have to return box with pens. So I did when all pens were empty. Not long after I had my near death experience.
      Somehow I got insurance, and it paid for insulin. My dose of insulin increased every three days. Finally it was 260 units. Now Medicaid was terminated. My man lost job, but his unemployment check was higher then $1100, poverty line to be qualified for Medicaid. Insulin delivery stopped. To buy insulin I need $2000 monthly. Even now when my man has a job we cannot afford to pay for insulin. Finally my man got the job, and health plan. So by now I do have insulin delivery every three month. I can still breath and going.
      Very often I can read how celebrity diabetics manage diabetes. I cannot. I can do it with insulin, but very often insulin out of option. Anyway, it is long, very long story to live with diabetes and have all junk medicine and attempt to manage it with life style, so by now I simple drift as it going, and try to avoid pain as much as I can. I gave up my membership in Bally. It is only about $100 a year, not so expensive and my man will pay it, I cannot use it. At first I could not work out, then I could not get there. Now I do have scooter and I probably could take a ride, but .... I cannot dress or change by myself. So simple, what I do have now work very well, but all come too late, and it is useless.

via Ravenvoron