Best Treatment for Pre-diabetics. October 31, 2018

     Most diabetics type 2, and pre-diabetics, very fool name for people with progressive and finally fatal medical condition, think, they are not fully diabetics. They think that diabetics are those who take Insulin. If they do not take insulin then they are not really diabetics. They will lose weight and they can do it. They can reverse diabetes type 2. "To Reverse diabetes type 2" is another trick our Art of Con Medicine play with us, just lab rats for them. Based on this Con Art people think, they will not need to take insulin. They will lose weight, and there are no way they will be diabetics who need daily insulin injections.
      This myth based on Con Studies, Con Science, and far away from reality. The matter of fact, if pre-diabetic will start to take insulin right after one was discovered that level of sugar in blood elevated, there would not be need in daily injections for the rest of the live. This fact our Con Art of Medical Care just refuse to admit.
      To see what is right and when it is going to in wrong direction, use your own brain.
For how long we told that with weight lose we will be OK, no diabetes type 2. Well, how it is diagnosed, there is no diabetes type 2? Just think about, you have pneumonia, and only one test you can take, level of temperature of body. You take anti-biotic as it is for flu. But it is not flu. Your lungs are already effected. Still, the temperature of body dropped. You stop to take medicine. Are you clear your lungs? How do you know it?
       Now back to diabetes type 2 which was 'reversed'. When? How MD was able to see that there is no diabetes type 2? By definition of cause. If blood sugar is not elevated then there is no diabetes type 2. So, take meter, put drop of blood, and see, are you diabetes free?
       There is trick. It is maybe OK for now. What if you get flu. or any other medical condition? We all do know that diabetics are easy to get infection, and very slow healing, why? Our immune system is not healthy, cannot protect us. Diabetes is not level of sugar in blood, as it is not the temperature of the body when one got pneumonia. It is limited secretion of insulin by our pancreas. This is why, when diabetics die out pancreas is very very small, shrank. Difference between diabetics and non diabetics. Every one do know it. This as how insulin was discovered in first place. Dr. Sir. Banting experimented with animals pancreas.
     Today human population is stronger, live longer. So, there are no wards in hospitals where children with diabetes in coma wait for transport to final destination. Very interesting point, why there were no public awareness at that time that diabetes kill and very fast?
      So, today what to do if one diagnosed with pre-diabetes? Do not rash into fitness club. Start Insulin with low dose, such as 10 units. And see, how your numbers going. Very soon it will be own experience how to take injections, how to count dose of insulin. And trust me, to take 10 units of insulin for the rest of your life is better then lost legs, or get stroke, or any other complications.

via Ravenvoron

41

41 ago today I was diagnosed with t1 diabetes. I remember certain things about my diagnoses and my admission memories - like social workers questioning me about a scar on my butt, a nurse dressed as a clown telling me I did indeed have diabetes, and being sad about missing Halloween. 

I’ve written about what I remember about my DX , my very first friend I met at the hospital with diabetes named Joe, my life pre and post DX. 

Every year since Diabetesaliciousness began, I’ve written a list of things that I love and am grateful for on my Diaversary - because it's a good reminder for me that I’m still here, I’m still alive, and there’s so much in life to love and be thankful for. 

Here's my list for 2018.

#########

1. I still love Halloween and I still love to dress up - It’s MAGIC

2. Little kids. Little make me smile and the majority of today’s teenagers give me hope for the future.

3. Reese’s Peanut Butter Cups - I love them - I always will.

4. Dancing  - I love to dance. I haven't danced as much as of late - I need to rectify that, ASAP.

5. Really good sex.

6. The beach in the winter when all the crowds are gone.

7. Swimming in the ocean - I feel free and at home and I love it.

8. The color yellow - it makes me feel all bright and shiny.

9. Cupcakes - they  are the perfect size treats and depending on the circumference and icing thickness - I can usually guess the carb count no problem! IT’S A GIFT.

10. Traveling - I love traveling - it exposes me to different places and people and it shows me just how similar people are while appreciating the different cultures.  Diabetes hasn’t diminished my love or my ability to travel. 

11. D Meet-ups. If I didn’t have diabetes I would have a lot less friends - and meeting up with diabetes peeps in real life is pretty damn special! 

12. Old movies. I'll focus on one, this time around. The Ghost And Mrs. Muir - I love this movie - it makes me cry every time I watch it. 

13. Making soup. OK, I make like at least 18 different types of soups from scratch - It's kinda my thing - and I try to add a new soup every year.  Some people are bakers. I am a "souper." 

14. Making soup for friends - it makes me feel like I’m helping and taking care of the people I love. 

15. Dogs. I love dogs. I don’t get people who don’t like dogs. I was bit by 2 different dogs growing up and I still love dogs. 

16. Twinkle lights.

17. Purple. Who doesn’t love purple? Purple is magnificent. Also: I look magnificent in purple! 

18. Prosecco - GOD I LOVE Presecco!

19. Wild ass guessing on a bolus for a food I have no idea the carb count on and having a BINGO bg a few hours later. 

20. Movie previews. I love them - have to be there for them - so don’t make me late!

21. Movies. I love going to the movies - but I have a really tough time watching a scary, gory movie. I love comedies, love stories, thrillers, "children's movies and historical dramas. 

But I can’t deal with gore. 

22. Oatmeal cookies. They are the most under appreciated cookies on the planet. Go eat one now and you'll see I'm right!

23. Cookies in general - except I’m not a huge fan of the ones with really sticky jelly in them. 

24. A really good cheeseburger - with cheddar, jalapenos, and raw onions.

25. Speaking of jalapenos  - I LOVE SPICY FOOD.

26. Live theater - it’s pretty damn special - we need to support theater, local, regional and broadway! 

27. Outdoor showers. It’s a beach thing. It’s amazing to take a warm shower outside and under the stars - I highly suggest it.

28. The perfect shade of lipstick. Lipstick makes me happy. You will rarely see me without it’s my talisman. 

29. Meeting new friends. I love making new friends. As we get older - our friendship circle becomes smaller - I’m doing my best to buck that trend because it’s stupid.

30. The colors green and blue. I love green. It make me feel healthy and my eyes POP when I wear green. Blue reminds me of people with diabetes, the ocean, and cornflowers. Blue makes me heart happy.

31. Gifts from the sea. As in shells, sea glass and rocks smoothed over by the sand - That Poseidon knows what he’s doing! 

32. The Ocean. I am drawn to it and I am part of it. The ocean calms me and sometimes it frightens me. 

33. Photography. I love to take pictures - it allows me to see things form different angles and POV. It’s one of the ways I try and express myself artistically. 

34. Naps. Naps are awesome. 

35. Cheese. I am a cheese slut. 

36. Writing in Sketch books. I take a lot of notes - writing in sketchbooks allows me to express my thoughts outside of the lines.

37. Libraries. A building filled with books; periodicals, art, computers and neighbors - a fellowship of bibliophiles that brings communities together.

38. Music. Music is part of my heart. There’s not a genre I don’t like when it comes to music. 

39. Daffodils. Daffodils are resilient, they give me hope and they remind me of my mom. 

40. Children with Diabetes FFL Conference(s). Green and Orange bracelet magic. 

41. My nieces and nephews - Individual pieces of art that have made my life better since I first became an Auntie - at the age of almost 6.

via Diabetesaliciousness

Metformin. Con Science. Con Medicine. October 31, 2018

Diabetes medication may protect against a common cause of blindness
https://www.sciencedaily.com/releases/2018/10/181029102836.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine%2Fdiabetes+%28Diabetes+News+--+ScienceDaily%29

     To see if medicine works for diabetic or not is very easy, if one take good care what to trust and when it is better to keep brain out of washing. We all do have glucose meters. If number on glucose meter go up, then medicine is better to be replaced. If numbers go down, then medicine is working, probably. So, when I took Metformin my numbers never dropped. In the contrary, diabetes type 2 progressed. At the same time cholesterol go up and up, TG went over 900. And vision. Yes, vision dropped. I could not read, and I could not use PC at night. Bad night vision. So, I dropped Metformin, common drug for diabetes type 2, started non common medicine for diabetics type 2, Insulin slow release Lantus Solo Star, and now all my numbers down. I do have good cholesterol, and good, normal A1c.
      It is more difficult with vision. One cannot stop medicine and see better, if the process of losing sight already started. So, it is safe for MD to Rx Metformin. There are also studies to back up con medicine. No one patient see what is going on, and why after taking Metformin it is so bad, metallic taste, and tiredness, and poison effect. Usually pations do not know, it is Metformin they take started to do the job, and this is not good for patient.
      Studies are different. They all the time found what con med needs to be found. Shame of it, but it is the fact. Every one do know it very well. Honestly to say, what is the punishment if article like this published in science e-journal, con art? No any punishment. Still, there are benefits. Authors put into own portfolio that they published articles. Authors got paid for every word they published. And there are public recognition, they are scientists, they published their studies's  findings.  Good for them all. What left for us?
      We cannot stop publications like that. It was in past, it is now, and it always be. What can we do? educate yourself. Use our own brain rather then let spaghetti  snug from our nose.
      At first, what Metformin is doing to reduce level of sugar in blood, the action to be used as diabetic drug? Metformin suppress liver to release glucagon into blood, so in case of low sugar diabetic has what? Coma. There is no glucose to be used to push blood or to stretch lungs to breath. To support the clime that Metformin does not work as diabetic drug it is best way to see what diabetics type 2 take. We all take Metformin, number one MD choice. The result is, diabetes type 2 progression. Less then 10 years after starting treatment with Metformin and life style modifications diabetic type 2 gone. It can be MI or stroke, does not matter.
      What is the matter, try to ask science if Metformin can prevent MI and stroke? Sure, it can. This Con Medicine can prevent all what you wish, or trust in MD that it will be in this way, and if it did not prevent then Metformin will treat the same medical condition it did not prevent to be developed. Perfect Art of Medicine. Or Con Art, if one wish to be more specific.
     Prove? well, MD use to Rx Metformin to fight obesity. every one who is in risk to develop diabetes take Metformin. Now look around, what do you see? How people around you, my dear reader, got skinny, if they got. Most of them take Metformin. Ask them. Or better take a look into own medical box.

via Ravenvoron

Obese mice lose a third of their fat using a natural protein. October 30, 2018

 Obese mice lose a third of their fat using a natural protein

 https://www.sciencedaily.com/releases/2018/10/181029084038.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine%2Fdiabetes+%28Diabetes+News+--+ScienceDaily%29

Obesity, which affects more than 650 million people worldwide, is the major driver for metabolic syndromes, which includes disorders such as insulin resistance, glucose intolerance, hypertension and elevated lipids in the blood.

 Looks like true. We all see on the streets more and more old people who are obese. I am obese, about 400 pounds. So, according to the authors, this is why I am diabetic type 2. My father was not obese. He died at age of 37. At that age I was not obese too. Now I am obese, and I am 66 years old. If I did not have insulin in my ref right now, and if insulin did not come to my medical box back in 2011, right now I would not be 400 pounds. I would be skeleton. This is reality about obesity.This real facts never mentioned. It is only presented that diabetes type 2 resulted by obesity. The fact that right now people with diabetes live longer, simple ignored. Also as it was in long long past, people with diabetes still not diagnosed. Why? It is nothing so difficult to diagnose diabetes, just take reading of glucose level in blood. Good question, why so many people with diabetes still out of diagnose to be diabetics. What our Medical Complex waiting for? More complications. More money. To secure the hook around our neck.

The treatments also reduced a number of obesity-related disorders in the mice, such as hyperglycemia -- excess blood sugar that is often linked to diabetes -- and eliminated the fat in their once fatty livers.

 Please pay attention to this so simple quite. What did it say? There are no definition and no understanding what is diabetes, how diagnose diabetes, how diagnose types of diabetes, type 2 particullarly every one talking about, and so so on. Diagnose of diabetes, according to ADA and WHO based on elevated level of sugar in blood. If sugar is elevated above 128 mg/dl fasting, or over 200 mg/dl random, it is diabetes. Personally I wish to say, at the time of diagnose diabetes is already in full bloom. 128 mg/dl, random, not fasting, is already diabetes. Our medical pro simple ignore this fact and pretend that "it is linked to diabetes". Really, what all that MD with titles and degrees are talking about?
Really, do they understand what they are talking about? At least they must be more careful to publish such absurd.

 The researchers found that this chaperone binds to three FGF proteins (19, 21, and 23) that are involved in the control of metabolism. FGF19 and FGF 21 signaling regulates the storage and use of carbohydrates (sugars) and lipids (fats). FGF23 controls phosphate metabolism.

       OK, now what? It is studies, and studies not all the time can be used in practice. What is in practice? In practice, more then 50 years Metformin is the number one doctor's choice to treat diabetics type 2.  Also, with history of hundred years, it still not known what is diabetes and how it can be diagnosed. Yes, it is progress. Now to diagnose diabetes MD does not ask victim to urinate in forest and look at if ants run to urine. They simple take drop of blood and look at the number on glucose meter. Progress. Now every one of us can diagnose yourself with diabetes. Sill, it is not sugar level what show the diabetes stage. It is level of insulin secretion. This test never ever run.For 100 years there are no studies how to diagnose diabetes. There are even no definition, diabetes, what is it? It is not the problem with metabolism.

 "We found that BP3 exerts a striking contribution to metabolic control," Wellstein says. "When you have more BP3 chaperone available, FGF19 and FGF21 effect is increased through the increase of their signaling. That makes BP3 a strong driver of carbohydrate and lipid metabolism. It's like having a lot more taxis available in New York City to pick up all the people who need a ride."

So pity  poor compare. But Wellstein looks enjoy it. What can I say? He is not so good in publishing papers. At least, he must admit it. Better to do not use what is our of your abilities.
      What really he try to say?

"With metabolism revved up, sugar in the blood, and fat processed in the liver are used for energy and is not stored," Wellstein says. "And warehouses of fat are tapped as well. For example, the job of FGF21 is to control break down of fat, whether it is stored or just eaten."

Sorry, in diabetics type 2 bodies fat stored in belly. Also it is stored in many places around body. Where that expression that fat stored in liver come from? From very limited brain ability. The same as NYC taxi drivers.  Really, what authors try to say? Nothing. It is just show up case. 

While the study results are exciting, additional research is required before BP3 protein can be investigated as a human therapy for metabolic syndromes, he says.

More studies needed. (more money needed. we will investigate all what no one  do need).

 The study, published in Scientific Reports, suggests that the protein FGFBP3 (BP3 for short) might offer novel therapy to reverse disorders associated with metabolic syndrome, such as type 2 diabetes and fatty liver disease.

---

Story Source:
Materials provided by Georgetown University Medical Center. Note: Content may be edited for style and length.

Thanks for nothing!!!!!!!!!!!!!!!!!!!!!!!!!!!

via Ravenvoron

Day-by-Day. October 30, 2018

      Yesterday it was sleep studies. I went to clinic to have test and probably I will have a new C Pop. My old one was Bi Pop. It is broken right now. It was broken sometime in Spring or early Summer. All that time after I did not have ether C Pop nether Bi Pop. Also even my old C Pop probably still working, all my masks are too old, and all trips are broken. So, it cannot be used.
      I need that machine. In Summer on camp very often I could not breath. My man woke me up. I sleep with very loud noise. It is not only snoring but also sort of whistle. It is water in lungs. Breathing is worsen when I do not use C Pop. I also start to grasp air because of there are no air in my lungs. Sometimes my airways collapse, and it is Asthma attack. I cannot breath at all. Once it happened on campsite. I was not able to stop caught, could not breath.It was good my man was around. I took one puff  of Symbicort after another. Symbicort is best for Asthma so far. But even Symbicort almost did not work. Finally, breathing resumed. I went to sleep right away.
      Today I sleep all day long. I did sleep very good in clinic. Technician is good man. He put me on sleep as soon as i come to office. He put on all wears, Put on mast very nicely, covered me with worm blanket, and I was very comfortable. In the early morning he come to me and very nice woke me up. My husband come for me. Test was over, so I could go home. Now the question is, would I have a new C Pop or not? Bi Pop worked too short. It is expensive machine. I asked only for portable C Pop that I could take with me on camp.All the time I denied, even I probably could have it, if doctor will say I need it.
       My sugar is pretty under control. Still, my kidney does not work very good, and I have edema. It is getting worse, or less, and I have no one idea why it is better and why it is getting worse. Probably I could do it with diuretics. I do not take this medicine. From my understanding many people who take this medicine later suffer because of kidney failure. It can be fatal.
       I still wrap my legs. Today it was too  much pain. Probably edema started to get higher, so wrap hold but it is too much pain. As soon as my man come home after work he unwrapped my legs. Now they take a rest. No pain.
      The spots where blood vessels were broken still in pain. I can feel this pain very very deep. When legs unwrapped for long time pain returns. I think it is only wrap help me to keep my two. What is important, why in hospital they do not do what I do by myself at home? Just why? When I was in hospital there were no wrap, only dressing on my wounds. Dressing fall down right after nurse put it on.
     Very often I think, why it is so? Our medical bills are so high, and what we pay for? The same as with clinics, it is only about sending bills. There is not too much for us.

via Ravenvoron

Golimumab Update

Golimumab (sold as Simponi) is an immune system modulator, which has been approved in the United States and many other countries for treatment of several autoimmune diseases, so testing it on type-1 diabetes makes a lot of sense.  Simponi has already been approved to treat rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, and ankylosing spondylitis.

Golimumab is a monoclonal antibody, which is an artificially created antibody which targets one very specific molecule in the body.   If a disease is caused by that molecule (or a cell marked by that molecule), then using a monoclonal antibody to target it is promising.  Golimumab targets tumor necrosis factor alpha (TNF-α) which causes inflammation, and is well known to be involved with type-1 diabetes. 

There are three on-going clinical trials of Golimumab (Simponi):

T1GER: SIMPONI® to Arrest Beta-cell Loss in Type 1 Diabetes
Who: 84 people aged 6-21 with honeymoon type-1 (first 100 days)
What: 52 weeks of treatment
When: Started Aug-2016 and expects to finish May-2020 (fully enrolled in Aug-2018)
Where: 33 sites in the USA (but they are no longer recruiting)
Run by: Janssen Research & Development

SIMPONI (Golimumab) Therapy in Children, Adolescents and Young Adults With Pre-Symptomatic T1D
Who: 30 people aged 6-21 with two or more autoantibodies, but no "classical" symptoms of T1D
What: 26 weekly injections
When: Started Oct-2017 and hopes to finish July-2021
Where: Colorado, Finland, Sweden  (they are still recruiting new people)
Run by: Janssen Research & Development

Targeting Beta Cell Dysfunction With Liraglutide or Golimumab in Longstanding T1D
Who: 30 people aged 18-50 who have had type-1 for more than 3 years
What: 8 weeks of treatment
When: Started Aug-2018 and hopes to finish June-2020
Where: Idaho and Washington  (they are still recruiting new people)
Run by: Benaroya Research Institute

Summary
I like this as a complete program.  These three studies cover Golimumab from many different points of view: people before they are diagnosed, honeymooners, and people with longstanding type-1. Two of the studies are for children 6-21 years old, and one for adults 18-50.  All are reasonable size.

The downside, is that we have to wait until 2020 to see results.  The good news is that by 2021, we'll have results from three different studies to look at.

Discussion
Curing type-1 diabetes in people with established type-1 is generally thought  to require two successes.  First the autoimmune attack must be stopped, and second beta cells must be regrown.  Golimumab targets the autoimmune attack, but is not known to regrow beta cells.  By itself, such a treatment might cure presymptomatic or homeymoon type-1 (because those people still have some beta cells), but is unlikely to cure established type-1.

Clinical Trial References:
  * https://clinicaltrials.gov/ct2/show/NCT03298542
  * https://clinicaltrials.gov/ct2/show/NCT02846545
  * https://clinicaltrials.gov/ct2/show/NCT03632759

Drug Web Page: http://www.simponi.com/
Drug Wikipedia Page: https://en.wikipedia.org/wiki/Golimumab
TNF  Wikipedia Page: https://en.wikipedia.org/wiki/Tumor_necrosis_factor_alpha

Joshua Levy 
https://ift.tt/29DuN3o 
publicjoshualevy at gmail dot com 
All the views expressed here are those of Joshua Levy, and nothing here is official JDRF, JDCA, or Bigfoot Biomedical news, views, policies or opinions. In my day job, I work in software for Bigfoot Biomedical. My daughter has type-1 diabetes and participates in clinical trials, which might be discussed here. My blog contains a more complete non-conflict of interest statement. Thanks to everyone who helps with the blog.


via Cure Research

What level of sugar is 'Normal'? October 28, 2018

The 'Normal' ranger of blood sugar level is from 93 mg/dl to 123 mg/dl. This is the range on my blood sugar strips identified as 'normal' range.
Blood sugar level from 33 mg/dl to 63 mg/dl identified as 'low' level of sugaar.
Blood sugar level from 239 mg/dl to 329 mg/dl identified as 'high' level of sugar.
       Now there is question: whaat to do with all that levels of sugar in blood?
What to expect in medical clinic or in ER when sugaar is in this ranger?
 How our Med Pro identify what treatment to apply when we do have these numbers of sugar in our blood?
       The mater of fact, there are no difference for Med Pro if patient has 329 mg/dl or 55 mg/dl.  In any case patient will sent home to adjust life style.
     For today post I try to take a look at the 'normal' level of sugar, and how 'normal' level of sugar is. We all do know that 'normal' temperature of body is 36.6C. What we also do know very well that if one got flu or any sort of any other medical complications, there are no ranger of body temperature as 'normal' of type 2. or any other types of temperature of body. There are two levels: 'normal' when patient is healthy, and abnormal when patent is ill. When temperature of body abnormally elevated one is assumed to be ill. The are different stages of being ill, but anyway patient start to take steps to get better. If it is flu and in the state of beginning, we do not go to ER, and we even go to work. When temperature is high we go to hospital.
      There are big difference between level of sugar in blood and temperature of the body. If I come to ER with 370 mg/dl the first question for me is, when I ate and what? Then there is time till blood sugar dropping, so .... yes, there is no need for any treatment. Sugar is not abnormally high. Most important to give Insulin, not high dose, but any dose. Sugar will drop right away. It is diabetic, not healthy person.
      When we are healthy out sugar still in 'normal' ranger regardless we recently ate or we are fasting. Sugar does not ranger very wide. No one non diabetic has sugar 140 mg/dl. regardless when and what one ate. Sugar will ranger from 70 mg/dl to 100 mg/dl. all in 'normal' range. When fasting is 128 mg/dl patient is already diabetic. No one MD identify this patient as diabetic, but easy to Rx 'healthy life style'. The question is why?
      Last 100 years there are perfect medicine to fight and cure diabetes. Why it is today 'diabetes epidemic'? There are no TB epidemic, no millions of flu victims in clinic with fatal level of body temperature. Why today people die because of Diabetes type 2? 80,000 diabetics lost lives every year due to diabetes, only in America. Why toll is so high? It is getting higher every year.
      There are billions spend every year to study diabetes and how to threat diabetics type 2. AT the same time there are still no clear cut how to diagnose diabetes type 2. Millions of diagnosed, and millions of non diagnosed diabetics type 2. How every one of us was diagnosed with medical condition we do diagnosed with?
      In my file it is said that I am diabetic type 2 with not controlled diabetes. What does it mean? When diabetes  considered to be 'controlled' and when it is not 'controlled'? The problem is, how to see if treatment diabetic type 2 does have effective or not? There are many publications how someone reversed diabetes type 2. The point is, how it was identified that there is no diabetes in former diabetic type 2? How it was diagnosed that diabetic type 2 diabetes type 2 free? There is no such diagnose, no any tools to diagnose diabetes. We use glucose meter to check up if entreat works or diabetes type 2 progressing. But this numbers on the meter are not reliable. If we do not know that one is diagnosed diabetic then one will not be diagnosed with diabetes.
      It looks like absurd. Of cause, why not? But it is not absurd to diagnose patient if one is ill or healthy  with lowest level of diagnosed range. I suggest, in stead to take fasting sugar as cut for diabetes type 2, let take starvation diet in one week,  (or two if it is possible) and see, if sugar will rise above normal range. Why not? If fasting is tool to diagnose medical condition for the level of insulin secretion then why starvation is not diagnose? Sugar will be even lower as I suppose it be.
       The problem is, we do not know this. That's right. We do not know what level of sugar after week of fasting do have healthy person, compare to diabetic type 2. These are studies which never had been  run.
      There are a lot of speculations how insulin secreted in our bodies. There are no studies how does it really secreted. All that fanny drawings that posted and published, nothing more then speculations. There are no prove. No one really every studied what insulin doing in blood, and how it is secreted. There are no studies how insulin increased in secretion after we ate. For how long sugar we took with our food transformed into glucagon or glucose or probably into something else.
      Still, every one do know how much every one of us must eat every day, day after day. When we go to fitness club our smart educators suggest to us 'to adjust' calories intake. How? Just how? No one tool how to do adjustment. But every one do know, we have to 'adjust'.

via Ravenvoron

Keep High Blood Sugar and High BP to Prevent Kidney Damage. October 27, 2018

In patients with type 2 diabetes at high risk for cardiovascular disease, targeting blood sugar to normal levels reduced the risk for macroalbuminuria, but it had no impact on more significant kidney outcomes such as serum creatinine doubling or the need for dialysis or transplantation. Targeting low blood pressures or the use of fenofibrate to lower cholesterol increased the risk for doubling of serum creatinine, although it had no impact on the need for dialysis or transplantation.
 Study questions certain treatments for diabetic patients at high risk for heart disease
by  American Society of Nephrology
https://www.sciencedaily.com/releases/2018/10/181025184036.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine%2Fdiabetes+%28Diabetes+News+--+ScienceDaily%29

        How do they studied these long term conditions? What would happen, and if did it really happened? It is all the time best way to understand what is right and what is not, to take a look at from another corner. So, what it is really about? OK, the normal level of sugar or BP does not reduce risk of kidney damage, right? So, what? What really studies try to say? I see nothing but that normal blood sugar and normal BP is not significant for my health.
     Well, probably in future I will use dialyses, probably I would not. Probably stroke will kill me before kidney damage would be fatal. Still today I do my best to fight high blood sugar, and keep it in target as much as I can. The matter of fact, my blood sugar is almost normal. If today I will go to any clinic no one will diagnose me with diabetes type 2. I do have perfect A1c. Blood pressure is high, higher then it must be. It was once that I was able to finally get it to the target. Then MD plied with my meds and now all mess up. I have severe headache every day, and all what I try to do right now, just keep going, to take Excedrin. As usual I do.
     About fenofibrate to lower cholesterol I can say, it never worked for me. Lipitor is great. Lipitor only. With this medicine my cholesterol returned back to normal level. Of cause, I no longer take Metformin. No water pills. About TG there is really confusing info. It is presented that high TG resulted by fatty diet, and only diet. The matter of fact, high TG level is result of heart complications. because of my heart is already damaged, TG all the time high.Once it was higher then 900. It is really very high. What MD said at that time? Eat right. It is universal for everyone for everything, financial crisis, health issue, education problems, just eat right, and there will no one problem in life.

"These results, along with those from the primary study which showed no benefit of the interventions on heart attacks and strokes, provide evidence against aggressive targets for glucose, blood pressure, and use of fenfibrate in adults with type 2 diabetes at high risk of cardiovascular events," said Dr. Mottl.

     There are only question I wish to ask: what they are talking about? Heart attack, stroke, and diabetes and kidney very different medical conditions. Every one is fatally danger. And what MD Dr. Mottl said? We do not need to treat diabetes because of it does not effect to prevent stroke or MI, or anything else. Does someone get the point of discussion? I did not. I did not get it.
      I take high dose of Insulin in injections. Do I try to prevent kidney damage? Not at all. I try to survive. I know what will happen if sugar is out of control. I do know also that I do benefit when I am able to control blood sugar. At least I am still alive. If there is no Insulin, and even I skipped one dose of it, I have to take higher dose later. If I do not, sugar get up and up. To prevent Asthma attack to be fatal, and many many other complications, I have to control blood sugar, very very aggressively.
    When I do not take my medicine to lower BP I do have very severe headache. It is so severe that there is no choice for me but to go to hospital.
      Because of I am chronically ill person I need to take all my medication, and try my best to keep BP, BS, and all other conditions, such as Asthma and Sleep Aphnea under control. If one of them loosen it effect to every one organ of my body.
     So, studies done to confirm what? What did they studied, and what did they found?
Money. More money needed. Out sweet blood is very profitable for them. Very beneficial for all Medical Complex.

via Ravenvoron

New discovery to instruct hungry cell to be not hungry. October 26, 2018

"After more than two decades of research by Melbourne scientists to get to this point, it is phenomenal to have achieved results that will ultimately benefit patients with the development of more effective therapies, particularly for those whose lives are dependent on a daily injection of insulin," he said.
 Insulin discovery a game-changer for improving diabetes treatments
 Walter and Eliza Hall Institute
https://www.sciencedaily.com/releases/2018/10/181024083332.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine%2Fdiabetes+%28Diabetes+News+--+ScienceDaily%29

More then two decades in studies, and finally discovery was made. Sound so exciting! Dr. Banting discovered insulin and its effect to treat diabetes for less then two years. In 1922 first insulin injection was delivered to diabetic and  Leonard Thompson and since millions of diabetic's lives were saved.
    Now what? How a new discovery will work, and what is this discovery about?

Published today in Nature Communications, the study reveals the first definitive 3D image of how insulin successfully interacts with its receptor -- a 'gatekeeper' for transmitting information into cells -- in a process that is crucial for instructing cells to lower blood sugar levels in the body. Understanding exactly what this process looks like could inform the design of faster-acting and longer-lasting insulin therapies.

I am wander, these instructions were given in written form or in oral? Was there some interpretation for cell how to use instructions? Also I am interesting, how this instructions would keep my blood sugar level under control?
      Then more I read studies like that and MD publications then more I see the absurd in all these studies and MD seems for me like those two charlatans who dressed The King Naked. Really, just think about, how image, any image, can instruct any cell what to do and how? Well, every one will LOL me loud that I do not understand the scientific method of studies and discovery. I really do not understand. I see only charlatanism and huge money pull out to the pockets of charlatans.
      There are two decades of study. They are not on minimum, wage. So, how much they were paid? Good $$$$$. There is only one question: why they finally discovered anything? After discovery there is no money as I suppose. Discovery done, it is time to use it. LOLOLOL!!!!!!!!!!!!
      Seriously, why this studies so important? Probably it will be more important to see if there is Insulin to signal to the cell how to open gates? If there is no insulin in cell then there is no way that the instruction how to lower blood sugar is effective in any way. At first there is no one who will read instructions and use them.
      Second, there is no task to lower sugar. It is simple no need in this. If cell is healthy then it works in healthy way. If there is something broken then at first it must be fixed, and only after that second part would do the job, to open the gates and to feed cell. Otherwise, if there is no insulin then there is no instructions needed how to use it.
    I think,  Walter and Eliza Hall Institute needs another two or three decades to understand this simple logic. For two decades, 24 years, and 80000 American diabetics lost lives to diabetes, how many lives were lost? 1,920,000. Why these lives were lost? Because of there are no insulin in blood to body to function. No insulin to read instructions how to lower blood sugar. I would LOL if I could. I cannot LOL. I cry.

via Ravenvoron

Day-after-Day. October 25, 2018

Life long run, but short live. There are many things happened in our lives. we do not think it is important, just regular day or night. With time we forget this event. So, we do not have our own history of life. we do know most important things which happened, Day Birth, Memorial, many other significant and not so significant events. Without good memory many of them vanish, and many of them stay in memory but poorly organized into line of events. Most important, this life gone with us, with our memories. all our experiences, achievements, understanding, we take with us, and there is no trace of it after us.
     It is not only sad, it is shame of us.
     Today my legs were wrapped.  They are wrapped all the time. I use to be wrap-free for day or two, just to let body to get smooth, and then my man wraps them. The problem is, it would be good do not sleep with legs wrapped. But in this case no one will be around to wrap them in the morning and I cannot do it by myself. At night very often there is pain, so severe I cannot sleep. Usually it is said we have to hold legs up. Do those who recommend this use to sleep with legs raised up? I do not think so. It is very bad for heart. Very soon we have this pain. Someone simple stop to rise sleep with legs raised. Other try very hard to stay be under role. What is important, we just do not know what is good for us, and what is wrong.
     I tried to be member of many diabetic's forums. Really, why they are all the same? There are posts one day after another, what every one ate, and what recipes they created to be diabetes type 2 free. Really, it is all too bore. But do not even try to brake the role. All that members will aggressively attack, and bark, and bull every one who try to say anything which is out of mainstream brainwashing. They are all the same, bullies. Diabetic's forums are the best to show up.
      At first, according to prime media and medical propaganda, diabetics type 2 developed diabetes because of too much sugar in diet. So, to get rid of diabetes type 2 is simple; Just starve yourself, and be strong. To support this claim many bullies post how they do it, get rid of diabetes type 2, reversed it. In one post lady posted that when she was diagnosed with diabetes type 2 she said to herself, no way she will be diabetic type 2. So, she created special recipe, and now she is diabetes type 2 free. The question is only one, why did she got to the hook in first place? Why she developed diabetes type 2 to the point to be diagnosed with diabetes? If I do not want to have cancer and it is possible to prevent with right meal choice, why do I need to develop this condition?
     Another lady proudly posted how did she lost more then 100 pounds. "If I could d that, then every one can do the same!" really, she was very proud. My question for this lady was only one: How did she got her 300+ pounds at the age of a little bit past 20?  In my time at this age I was size "S" and less the 100 Lbs. But I was diabetic. I am 380 lbs right now. I passed MI. strokes, not one, and hardly was able to survive. I did it. I proud I had done it. I really not do care too much if I am 100 Lbs or 480 Lbs as long as my blood sugar is normal. It is right now. Am I diabetes type 2 free? Not at all.
      Every time when I forget my insulin shot I have high sugar, higher then normal level according to mine current state. This is trick MD and media play with us. They pretend that with weight loss it is possible to be diabetes type 2 free, how? How do they confirm, diabetic type 2 diabetes-free? There are no test to confirm what time of diabetes patient diagnosed. Why? all tests and all diagnoses based on level of sugar. Level of sugar is different all the time, very unstable. It is even when taken one drop after another results are different. So, how it is possible to confirm, patient is diabetes type 2 free? Not possible.
     Still, there are posts one after another, someone reversed diabetes type 2. Media confirm this clime, this person really done it. Really, who trust in Media? I do not.
       This is what I suggest every time for every one: run your log book. It is good for us, every one of us to have our life history recorded. It can be very helpful for all family, even those we do not know yet, in future. It can help to someone to learn how to deal with the situation one is, collective experience. Well, probably no one ever will read my log books. It does not matter. I do believe it helps to me. I hope my posts help to someone else. So, I do part of my job.

via Ravenvoron

Why today is Diabetes Type 2 Epidemic? October 24, 2018

In just a generation, diabetes has gone from rarity to epidemic, a catastrophic turn that presents urgent question: Why are so many suffering, and so suddenly?
    The fact is that today, in spite of all loud cry out, diabetes is not so devastated as it was 100 years ago. Why today so many diabetics? Author of the book present it as modern population consume too much sugar. Another point he present that diabetes can be prevented and reversed. He suggest solution, intermittent diet.
      The book is interesting to read. It collected all scam and all 'old women' talks what is diabetes and how to refuse to be diabetic. They did it. All 'old housewives' done it. So, every one can do, refuse to be diabetic type 2, and do not pull money from taxpayers. Author even present a little bit history of diabetes, back to 250 BC.
     First point, in past diabetes effected mostly children. Why? When child die how this child would be adult? In present time it is not only diabetes type 2 epidemic. It is survival. Children no longer in such danger like it was back to 250 BC. But author ignore the fact, it is 2000, long time after 250 BC.
       In addition to the fact that children survive today, they are healthier and live longer. This why they diagnosed with diabetes as adult. To be diagnosed as adult mean to be diabetic type 2, not type 1. So, the fact that today we do have diabetic epidemic which spread fast and wide, is myth. The matter of fact, today there are many diagnosed diabetics, but longer diabetic's life. Compare with rarity of diabetes in past.
     Why diabetes was named as it is excessive urination? This mean that sugar is so high, near fatal level. Before sugar rise so high diabetes is not visible. Victim of diabetes suffer, weak, ill, but there is no diagnose of diabetes. Even it is already visible that victim has diabetes, there is no treatment so, there is not so much difference to be diagnosed or not. It is all the same.
      Another very important claim by author is, that diabetics eat too much sugar. I do not know about 250 BC how much sugar diabetics ate. What I do know that wild animals do not eat sugar. Also they are not obese. Why wild animals have diabetes? Cab can be born with diabetes. It is very rare, why? because of if cab born diabetic this baby has no chance to survive. Mother will not feed baby. So, diabetes rarely spread among wild animals.
     In contrary, in zoo animals die because of diabetes. Why? They live longer, getting older. In spite of the fact they are no longer so strong, they have staff who care for them. Domestic and animals in zoo can live with diabetes. Wild animals almost cannot.
      With all that noise that diabetes type 2 resulted by obesity and too much sugar eating, the fact is right opposite. With health care and good nutrition children became healthier adults. If today adults will be treated with right regime of insulin then tomorrow less children will be born with diabetes type 1. Less adults will develop diabetes after 30th. Diabetes will stay with us. It is part of aging process. Somehow people die, no one of us live forever. The point is, when to die, at age of 30 or at age of 90?

via Ravenvoron

Misdiagnosis of Adult-Onset Type 1 Diabetes Is Common. October 23, 2018

Misdiagnosis of Adult-Onset Type 1 Diabetes Is Common.
 by Miriam E. Tucker
https://www.medscape.com/viewarticle/903605?nlid=125692_1521&src=WNL_mdplsfeat_181023_mscpedit_wir&uac=164666HZ&spon=17&impID=1778358&faf=1#vp_2 

 Both Thomas (Nicholas J. Thomas, MD of the University of Exeter, United Kingdom.) and Dayan (Colin Dayan, MBBS, professor of clinical diabetes and metabolism, Cardiff University School of Medicine)  noted that there is no perfect laboratory test to distinguish between the two types of diabetes, as C-peptide can initially be positive in type 1 diabetes — although it's more definitive after about 3 years — and autoantibodies can be present in some people with type 2 diabetes and absent in some people with type 1 diabetes.

      So, there are mo tests to define what type of diabetes MD diagnose patient.  How MD possible able to treat patient without correct diagnose? The results are in Mortality tables by CDC. Diabetes type 2 is number 7 cause of Death in America. Why?
     Beside the correct diagnose there is correct or wrong treatment. If treatment correct then diabetic does not progress to insulin deficiency. If treatment wrong then, .... then less then 10 years after being diagnosed with diabetes type 2 diabetic gone if one did not start Insulin injections. If one is fortunate and was able to get MD who is willing to heal rather then keep diabetic in own stable, then diabetic type 2 will live. Then early insulin therapy started then more healthy diabetic will be and develop less complications when Diabetes type 2 progresses. Now, what Med. Pro think about it?

But session moderator Colin Dayan, MBBS, professor of clinical diabetes and metabolism, Cardiff University School of Medicine, is a bit more hesitant about putting people on insulin straightaway. "Insulin is a very difficult drug to use...I don't want to start someone on insulin if they don't need it," he told Medscape Medical News in an interview.

        I take insulin more then ten tears by now. I strted form 11 units at bed time because of I am diabetic type 2, and highest dose I injected was 720 units withing 24 hours. Why insulin is difficult drug to use? Because of insulin started so late that many complications already developed. Also there are swings high/low, high sugar level and then after insulin injections sugar in blood dropping too low. Why this happened? Because of human body is very sophisticated and very complex. What our Med. Pro educate us is wrong. They pretend that if sugar is low then a few spoons of sugar taken right away prevent sugar from dropping lower and lower. 100 years after insulin discovery Med. Pro still do not know that insulin and sugar is not in direct proportion dependency. It is not true that if today  right now my sugar in blood is 44 mg/dl then I have to take two or more spoons of sugar. If everything was so simple then just develop table how many spoons of sugar diabetic need to take according to blood sugar level. Everyone do know, there is no table like this, why? Because it does not work in this way.
      Now, I used to have 1,000 mg/dl in blood. This level was not one day, but day after day, a little bit less, but steady up and up. With every dose of insulin sugar dropped. Lowest I detected on my meter was 38 mg/dl. Of cause, because of I am diabetic type 2 I never was educated how to check up ketoacidosis. So, it never was detected, even I was in hospital. Really, I scared to go to hospital.

 The issue, Dayan said, "is whether any damage is done by waiting, using tablets...There are certainly patients where we suspect that they may have type 1 diabetes but they didn't present with ketoacidosis, so we might start them on [an oral diabetes medication] with close observation, unlike somebody where we're confident they've got type 2 diabetes...You need to keep your eyes open the first 3 years."

       At first I wish to ask, with oral medication how diabetes progressed or reversed? It is easy to see that if medicine work then A1c will go down. The numbers on glucose meter will go down. The number of medication in diabetic's medical box will decrease. BP, cholesterol, TG, and all other medical complications will not be developed with right medicine.  If medicine is wrong then with every day diabetes will progress.
     Now there is another question. Why MD pretend that it is right to let diabetes to progress during next 3 years after diagnose with diabetes type 2? Maybe it is not diabetic type 2 but LADA or MODY, or Type 1 diabetic? Most important that regardless of diagnose level of sugar in blood is great predictor if diabetic progress into complications development, or slow getting away from them.

But one key sign identified from this study is rapid deterioration in glycemic control despite use of oral glucose-lowering medications. "Rapid insulin requirement should alert the clinician to the possibility of type 1 diabetes," Thomas said.

      Say me, when it is happened and how insulin requirement  was identified? I follow all ADA recommendations for many years, and there are no insulin requirements when MD must start diabetic type 2 on Insulin. As long as I follow ADA publications there are all the time 'first line medication', and what does it mean? If diabetic come to clinic with 700 mg/dl or 599 mg/dl, would this diabetic type 2 started on Insulin Therapy? Not at all. even A1c=12.2% diabetic type 2 still take oral medicine, rapidly progressing to the Mortality Table by CDC.
    Still, I do not get the point, why do not start insulin injections as soon as sugar started to go out of normal range? What wrong with this policy? Profit.
     Diabetics are very profitable for Medical Industry. If there are no diabetics where high income will come from? Healthy patient no longer paying patient. It is difficult to get client into clinic if one is healthy. Diabetics type 2 are not healthy. We have wide range of complications. Then more we progress into insulin deficiency then more medicine we need. Then deeper we are in diabetes development then longer it takes to get out of this hole.

The correct diagnosis is important, he (Thomas)said, because patients need insulin early in order to avoid diabetic ketoacidosis. Also, even once they do receive insulin treatment, it's important to correctly distinguish the diabetes types as the respective insulin regimens and the type of education the patient receives differ considerably.

      Sorry Mr.  Thomas. DKA can be reversed very fast, but damage which done by wrong treatment and wrong diagnose not only will last too long and is too difficult to fix, but it can be fatal, or not reversible. This is another pro to start insulin as soon as diabetes was diagnosed. There is no wrong treatment if insulin taken as first line of therapy, regardless of any type of diabetes. So, it is win-win situation. The problem is only one, if there is no diabetics in clinics then there are no clients in it, or too little of clients in hospitals and clinics.

via Ravenvoron

Day-by-Day. October 23, 2018

     Nothing new or interesting. The same day after day. I take Excedrin to fight headache and to avoid stroke. Very often headache at night and I cannot wake up, just keep sleeping. Every one can LOL me that if I still sleeping then headache is not so bad. No one of us do know for sure how coma looks like inside when one is is coma and then simple die. Why people die and how? They do not post, do not share what happened after last things they remember. Also no one do know what is last step before we stop to breath.
     Headache every night, and every day if I do not take Excedrin. I try to take as less as I can. My teeth are crashed and cracked. I hardly able to eat. My last dentist done good work, but he could not fix all the problem. I have to wait for the new year. But I even do know how this will work. After all job was done office called and now I do have outstanding balance. Why? Before any service done I have to know what it will cost and pay for this service. I do not pay post=phoned bills. Well, I think I am in hot water now.
    For stroke prevention I need medicine to fight blood clotting. It is not possible to get without Rx from MD. No one MD take responsibility to Rx to prevent stroke or heart attack. They all 'prevent' diabetes, MI, stroke, and even re-verse diabetes type 2 with starvation. To Rx medicine which will prevent death, coma, or deep complications... no it is not work for MD. This is why diabetes type 2 in top of ten leading cause of Death. Start to Rx Insulin as soon as sugar in blood get out of normal level, and then there will not MI or strokes. No, it does not work in this way. we have to build up sugar in every cell of our bodies, run over limit our body system can clean up, and finally give up developing body over any reasonable size. Water no longer go out in spite of all Invokana and water pills we have easy to get Rx. The medicine which can do the job and keep us in good shape and good health is not in our medical box.
     Right now I have to have Insulin delivery. Time for delivery is up-graded and pushed off. In addition to problem with Insulin I do have problem with other medicine. I do not have Rx to anti-depresants, to heart, to nitrostat. It is easy to say that we cost too much for society, but there is no one post or publication who much our family pay to support diabetics type 2. My man pay all co-payments for my medicine and my medical visits. I cannot work, do not have Medicaid or SSI. He is old man, but he still working. Somehow we have to pay bills and pay for medicine for me.
    It is posted many times that if diabetic type 1 skip one insulin shot diabetic type 1 even may die. The dose of insulin for diabetics type 1 less then 50 units. Many of them take less then 10 units. No one will die because of skipped insulin shot. Also they like to post all drama how it looks like to have low sugar. There is no drama if sugar low when one take less then 10 units.  No one post how low sugar looks like when diabetic type 2 inject more then 200 units daily dose. Highest dose I injected was 720 units withing 24 hours. No one diabetic type 1 inject such high dose at home. I do. I even did not go to hospital. They will not let me to inject such high dose of insulin. They simple let me go home with sugar over 1000 mg/dl. They will discharge diabetic type 2 and send me home, at night, alone.
     I think, I am depressed. It is so complicated when insulin is not in box.

via Ravenvoron

Getting Back To Exercising After An Injury

Ever since I broke the joint of my pinky toe over the summer, (the bone healed, but I developed peroneal tendinitis and had to go to PT,) my exercise has basically consisted of regular day-to-day walking - as in walking around normally and doing “normal stuff - with lots of resting and icing in between, daily stretches and some swimming. 

Luckily, I’ve kept an eye on my food intake, kept my eating healthy (at least for the most part,) and haven’t gained any weight - I’ve even lost a couple of pounds. 

But I’m not loving how my weight has redistributed - even though my jeans are a size smaller than they were last year.

My PT gave me the OK to start light workouts 3 weeks ago. Walking 1.0 to 1.5 miles in my first workout, then adding to it as I start to feel more comfortable. 

I'm going to let you in on a little secret. 

I haven’t done it because I’m afraid. 

My toe feels tender and a little weird sometimes since it no longer lays flat on the ground - because that’s what happens when you fracture the little toe joint the way I did - and I was told that it would heal that way when I went to the Dr. after I broke it.

I’m nervous about exercising and I’m not sure why, but I think it’s because I’m afraid that since it will always look different, it will always feel different. 

And I’m afraid of inflaming the tendons - which is the main I had to go to PT in the first place.

My PT told me that one day I’ll wake up and I won’t even think about it - and I know she’s right. The same thing happen with my CT and trigger surgeries . 

One day I woke up and I didn’t think about using my hands to lift heavy things - I just did it. 

I need to stop thinking and comparing and start DOING  - and not just when it comes to exercise either! But one issue at a time.

Bottom Line: Exercising and breaking into a sweat makes me feel good mentally and physically, it's also good for my diabetes and my heart, not to mention my glutes!

And I need to embrace other forms of exercise, instead of stubbornly focusing on my go-to, which is walking. I need to get on my bike, maybe consider the elliptical, and start up with weights again. Cleaning and organizing the black hole that is my storage closet wouldn't kill me either. 

The simple act of writing about my fears and sharing them with you guys makes me feel better and more positive about the whole sitch.

I'm glad I could talk it out with you guys - thanks for listening and for making me feel better! Xoxo

via Diabetesaliciousness

Why does diabetes cause heart failure? October 21, 2018

Why does diabetes cause heart failure?
Source: Loyola University Health System
https://www.sciencedaily.com/releases/2018/10/181018095420.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine%2Fdiabetes+%28Diabetes+News+--+ScienceDaily%29

      Really, why diabetics type 2 die? We shouldn't. All what we need just stop to eat, and we will be just fine. Diabetes type 2 can be easily reversed with low carb low calorie diet. There are studies, and all studies show, many people who do not want to be diabetics reverse diabetes type 2.  Those who did not stop do not post or publish any articles in med. journals.
    Once I posted on Spark People.com that 80,000 diabetics die every year due to diabetes. I got very interesting response: diabetics do not die because of diabetes. They die because of complications of diabetes. Well, if we will take into account all cause then there will be much more then 80,000 every year. It is estimated as 200,000. Heart failure, heart attacks, MI among them. Other victims die because of stroke, or lung complications such as Asthma or pulmonary embolism. In any case it is clots which stop in any blood vessel. Heart is just one complication from many.

A new Loyola University Chicago Stritch School of Medicine study reveals how, on a cellular level, diabetes can cause heart failure. The findings could lead to medications to treat and perhaps prevent heart failure in diabetes patients, researchers said.

     I have no one idea what researcher studied, but there is very simple study can be done. Try to ride your car without gas and see how good your engine run.  In diabetic's patient heart simple has no energy, no gas to push blood. So, regardless what medicine will be developed to prevent heart filure, no one medicine will work. Diabetics' hearts will stop when sugar is very high, too low, or high sugar is too long in blood.
     The real question is, why with all publications diabetes mentioned without level of sugar in blood? When sugar level is not too high, but above threshold level diabetics do not die because of heart failure. This condition develops when diabetes already type 2, meaning that dose of insulin is higher then 200 units a day in injections. When sugar is high, and remember, every one out of two diabetics type 2 not diagnosed today, blood is very dense, heavy. thick, syrup-like. This blood needs to be pushed with more energy then regular blood. In contrary, diabetic type 2 has no energy. There is no insulin in blood to convert high blood sugar into energy. Two causes combined together bring just perfect situation for heart finally give up.

via Ravenvoron

LADA, type 1, or type 2 Diabetes? October 19, 2018

Informally termed "type 1.5 diabetes," latent automimmune diabetes in adults LADA(LADA) is a relatively common disorder that shares features of type 1 diabetes (T1D) and type 2 diabetes (T2D). LADA is commonly misdiagnosed as T2D, as it presents in adulthood but doesn't initially require insulin treatment.
 First GWAS analysis of 'type 1.5 diabetes' reveals links between immune and metabolic disease
 Source: Children's Hospital of Philadelphia
https://www.sciencedaily.com/releases/2018/10/181017145320.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine%2Fdiabetes+%28Diabetes+News+--+ScienceDaily%29

There are two points I wish to consider.
At First, how common LADA to be diagnosed? Not even MD do know about this type of diabetes.  At least not every one who treat diabetics.
It is also not too many diabetics who diagnosed with LADA.
Finally, how often LADA discussed in public? On posts or in any Media?
If I take it all into consideration this does not sound for me to be 'common disorder'.
Second, why LADA does not require Insulin?  Because of regardless what diabetic said and wish to have as treatment option, no one MD will Rx Insulin for diabetic with LADA. LADA is not for children,. It is adults who diagnosed sometimes with LADA. Probably just because of some personal issue, such as diabetic's demand of Insulin as treatment option, or very good understanding of MD who do know very well what is diabetes about and wish to do the job without hurting own neck.

The new research, the first genome-wide association study (GWAS) of LADA, represents a large international effort, with dozens of co-authors from nine countries.

WOW! With these money how many diabetics could be cured with Insulin? Thousands. Not just treated but cured. And what after? No more studies needed. You must be kidding, yea? It is free money. And no any responsibility, no malpractice, nothing. Just pretend like professor R.Taylor, you see Beta Cells on MRI image.  COOL!

While the current study is larger than the 2017 analysis, and had genome-wide reach, both studies found the strongest genetic signals in LADA were associated with T1D, the autoimmune form of diabetes that usually presents in childhood and requires treatment with insulin. The current analysis also found genetic signals linked to T2D, the metabolic type of diabetes, more typically appearing first in adults, and by far the most common type of diabetes.

Why type 2 diabetes is metabolic type of diabetes? It is diagnosed the same way as Diabetes type 1. It can be perfectly treated with Insulin in injections. It can be cured in the same way as type 1. As one once said, if it is sound like duck, smell like duck, lucks like duck, then it must be duck! 

 Overall, the team found that the strongest genetic signals in LADA were mainly shared with established variants known to be linked to T1D. However, the researchers discovered a novel locus with genome-wide significance near the gene PFKFB3. This gene codes for a protein that regulates both insulin signaling and glycolisis, the chemical reaction that yields energy from glucose. "This finding points to how variants at PFKFB3 may help to drive LADA," said Cousminer, who added that because the gene's product not only impacts metabolism (a key feature of T2D), but also regulates inflammation in autoimmune disease (a key feature of T1D), "this protein therefore appears to sit at the intersection of both major types of diabetes."

 Personally, I will stop on this point. I am not interesting in Con-men who try to sale A New Dress For King. My point is very simple and very clear: if Insulin in injections can treat all types of diabetes, and no one test ever done to diagnose type of Diabetes I do have, then I am better to take General type of treatment which easy to apply and which can be applied for every type of diabetes.
     So, I take Insulin in injections, every day, day after day.
What did I learn since I injected my first dose of 11 units? It works. Without Insulin I would not be posting now. I would not be alive.
Today with 380 pounds I walk on my two legs. Not fast, not far, not long, but I am able to take short walk.
I do not wear glasses. I use glasses for reading, but only for reading. My vision is pretty good and still serve me well.
I am not amputee. Two years ago clot stopped in my legs, and wounds were developed. I still fight this condition today. Every time I wear wrap to prevent old wounds to pop up. But regardless, I do walk on two legs, and I am really happy I still do.
There are much more what is going on. Something worse, something better. I was born diabetic to diabetic father. I was diagnosed with type 2 diabetes short then 20 years ago. Is this right diagnose? Probably it is LADA? Maybe it is type 1? I do not know. And I do not care what is in my file. What I do care is what is in my Medical Box. There are Insulin, Lantus Solo Star. As long as Insulin is in my Medical Box, in my Ref. I can breath, I can live.
       I really do not care that someone look at me and see 400 pounds in wheelchair. They do know very well, this is why I am disable, I do not behave! In contrary, I do have very good care for myself. I used to be ill full my life. Now with almost 400 pounds body I am healthier then ever.

via Ravenvoron

People with diabetes or Slaves of Political and Medical Power? October 18, 2018

Diabetes is a complex, chronic illness re-

quiring continuous medical care with mul-

tifactorial risk-reduction strategies beyond

glycemic control.
 http://care.diabetesjournals.org/content/diacare/suppl/2017/12/08/41.Supplement_1.DC1/DC_41_S1_Combined.pdf
        Ask me, what is Diabetes. It is constant booing and humiliation, pain and fear of  get to the point to be in nursing facility absolutely  dependent of those  who never care. It is not that I do fear of death. Death is just part of our life. we all will die eventually. More then anything I fear to be completely dependent, not able to turn from one side to another on my bed, even not able to leave my bed, develop never healing wounds, and live in desperate desire that this life finally over.
        I fight. I do it every day, one day after another. This fight come with price, and I pay it. In every diabetes education posted or published it is said what diabetes doing in our bodies. There are symptoms of diabetes, and every one do know them. What no one do know or ever posted or published how do we feel when every one do know, diabetes is wrong behavior, wrong life style people with diabetes chose to live. We are not pleasantly looking. Diabetes dramatically changed our appearance outside and inside. And we are very profitable for Medical Industry. Even those who do not have medical degree benefit on our sweet blood. We are very big part of economic and politic.
      What benefits do we have as being Big Part? We are getting worse with every day. Big Boys are making policies, and we pay the price. Every one blame diabetics type 2 that we are very expensive for society to care for us. What care do we have? Is this really care for us, or it is exploitation of our complex chronic illness? are we ill people, or we are Slaves of Human Society? Really, who we are, diabetics type 2?

      Type 1 diabetes (due to autoimmune B-cell destruction, usually leading to absolute

insulin deficiency)

      Diabetics type 1 all the time insist, they are not the same as we are, diabetics type 2. They do have diabetes because of their immune system for some reason no one do know which attack own insulin secreting B-cells. This classification makes diabetics type 1 feel sort of being special. At least it is not they are, whom to blame they are diabetics.
       I would take it for granted if I do not know simple fact: with Insulin injections  with time dose of insulin getting lower. It is what all type 1 diabetics post, it is in my case, and it is in history of diabetes development. Insulin administered in injections lead to decreased need in dose of insulin, prevent development diabetes complications, and prolong diabetic's life.
      This is fact. If so then say me, how it is prove that diabetes type 1 lead t absolute insulin deficiency and B-cells distraction? Yes, eventually if left untreated diabetic type 1 will pass away painfully and shortly. With proper treatment regime diabetic type 1 enter into Honeymoon phase, and live long healthy life.

Type 2 diabetes (due to a progressive loss of B-cell insulin secretion frequently on
the background of insulin resistance)

        So, this is classification of diabetes type 2. If this is classification of illness, this illness must be diagnosed. How Insulin Resistance diagnosed? There are no tests for diagnose Insulin resistance. No one.  Level of sugar in blood can be diagnosed. It is only diagnose for diabetes. It cannot be used to diagnose type of diabetes. C=Peptides level can show the level of insulin in particular moment. This test prove nothing how insulin resistant  body system is. It is only test what is the level of insulin in blood in this moment.
       When we start to eat, level of insulin rises. Blood test usually fasting. It is lowest level of sugar in system. All diabetes definition, and it is posted right above, the B-Cells and insulin secretion. Now, why test for insulin taken at the time when it is lowest in demand? Highest demand, when we started to eat, avoided to test. Is this really too much insulin in diabetic type 2 blood? There are never test to check it up and prove this theory.
       In contrary, after diabetic type 2 takes Glipizide, SU type of medicine which force B-cells to secret insulin, C-Peptide level in blood is high. This taken for granted that it is Insulin Resistance, too high level of insulin in body system. With time B-Cells in diabetic 's type 2 body destroyed. There are no insulin in secretion, regardless how hard SU try to force them to secret it. There are no B-Cells to secret insulin.
       This is why diabetics type 2 die less then withing 10 years after being diagnosed with diabetes type 2.
        It is ADA recommendations how to provide care for people with diabetes. Now there is my question, who we are?
Do we are people with chronic illness requiring continuous medical care or we are slave of human society to be used for economical, political, and social needs of humanity?

via Ravenvoron